Gene Information

Name : CP0527 (CP0527)
Accession : NP_445071.1
Strain : Chlamydophila pneumoniae AR39
Genome accession: NC_002179
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 569103 - 569867 bp
Length : 765 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAAGCCGGAAGAGTCTGAGTGTCTGTGTATTGGAGTTTTGCCCGCACGCTGGAATAGCAGTCGCTATCCAGGAAAGCC
TTTGGCTAAAATTCATGGAAAAAGCTTAATACAAAGAACTTATGAGAATGCTTCCCAAAGTTCTCTATTAGATAAAATTG
TTGTTGCTACTGACGATCAGCATATTATCGACCACGTGACTGATTTTGGTGGTTATGCAGTGATGACTTCTCCTACATGT
TCCAATGGTACAGAACGCACAGGTGAAGTAGCTAGAAAGTACTTCCCTAAAGCTGAGATTATTGTAAATATTCAAGGTGA
TGAGCCTTGTCTAAATTCTGAGGTTGTCGACGCTTTGGTTCAGAAGTTGAGAAGTTCTCCTGAAGCAGAACTGGTGACTC
CTGTGGCACTCACGACAGATCGTGAAGAGATCTTAACAGAAAAAAAAGTAAAATGTGTTTTTGACTCTGAGGGAAGGGCT
CTGTATTTTAGTCGCAGTCCTATTCCTTTTATTCTTAAAAAAGCAACCCCAGTATATCTCCATATTGGAGTATATGCTTT
TAAAAGAGAGGCTCTTTTCCGCTACCTACAGCATAGCTCAACTCCTCTAAGCGATGCCGAAGATCTTGAGCAATTACGTT
TCCTAGAACATGGAGGCAAGATCCATGTGTGTATCGTAGATGCAAAAAGTCCCTCTGTTGATTATCCAGAAGACATAGCT
AAAGTAGAACAATATATCACATGCCTTTCAAATGCATATTTTTAA

Protein sequence : 
MKPEESECLCIGVLPARWNSSRYPGKPLAKIHGKSLIQRTYENASQSSLLDKIVVATDDQHIIDHVTDFGGYAVMTSPTC
SNGTERTGEVARKYFPKAEIIVNIQGDEPCLNSEVVDALVQKLRSSPEAELVTPVALTTDREEILTEKKVKCVFDSEGRA
LYFSRSPIPFILKKATPVYLHIGVYAFKREALFRYLQHSSTPLSDAEDLEQLRFLEHGGKIHVCIVDAKSPSVDYPEDIA
KVEQYITCLSNAYF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 5e-32 42
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-32 42
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 4e-32 42