Gene Information

Name : hemC (Cj0545)
Accession : YP_002343976.1
Strain : Campylobacter jejuni NCTC 11168
Genome accession: NC_002163
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 507304 - 508227 bp
Length : 924 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAAGCTTATTATTGCAACAAGAAAAAGTCAATTAGCTCTTTGGCAAAGTGAACATGTAGCCCAAATTTTAAAAAATAC
ACATCAAATTGAAGTGCTTTTAGAAGGTTTTAAAACAAAAGGCGATGTTTTGCTTGATTCTCCTTTGGCAAAAATTGGTG
GTAAAGGACTTTTTACAAAAGAACTTGAAGAAAGTATGTTAAGAAAAGAAGCACATTTAGCAGTGCATAGTTTAAAAGAT
GTGCCTAGTTTTTTTCCTCAAGGTTTAGTTTTGGCAGCGGTAAGCAAAAGAGAGCAAAGCAATGATGCTATGCTAAGTCA
AAATTATAAAGATTTTCTTTCTTTACCAAAAGGTGCAAAAATAGGCACTACTAGTCTTAGACGCAAGATGCAGCTTTTAT
TATTAAGACCTGATTTAGAGATTATTTCTTTGCGTGGTAATGTCAATTCTCGTATAGAGAAATTAAAAAATAATGATTTT
GATGCGATTATTTTGGCAATGGCGGGAATTAAACGCTTAAACTTAGATAAGCAAGTGAATTTTGTTTATGAATTTAGCAA
AGATGAGCTTATTCCTGCGGCTTCTCAAGGAGCTTTAGGTATAGAAAGCATAAATGATGAAAAAATTTTAGAACTTTTAA
AATGTTTAAATGATGAAAATGCTTTGATTGAAACAAGCATTGAAAGAGAATTTATTGCTACTTTAGAAGGAGGTTGTCAA
GTTCCTATAGGTATTAACGCAGAACTCTTAGGAGATGAAATTTGTGTGCGTGCGGTACTTGGACTACCCGATGGAAGTGA
AATTTTAAAAGATAAGAGAATGATTAAAAAGAATGATTTTAAAGGTTTTGGAGAGAGTTTGGCTAAGGAGTTTATTGCTA
AAGGTGCTAAAGAACTTTTAAAAAAAGCTGAGAGTATGATATGA

Protein sequence :
MKLIIATRKSQLALWQSEHVAQILKNTHQIEVLLEGFKTKGDVLLDSPLAKIGGKGLFTKELEESMLRKEAHLAVHSLKD
VPSFFPQGLVLAAVSKREQSNDAMLSQNYKDFLSLPKGAKIGTTSLRRKMQLLLLRPDLEIISLRGNVNSRIEKLKNNDF
DAIILAMAGIKRLNLDKQVNFVYEFSKDELIPAASQGALGIESINDEKILELLKCLNDENALIETSIEREFIATLEGGCQ
VPIGINAELLGDEICVRAVLGLPDGSEILKDKRMIKKNDFKGFGESLAKEFIAKGAKELLKKAESMI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-54 48
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-54 48