Gene Information

Name : lysS (Cj0401)
Accession : YP_002343838.1
Strain : Campylobacter jejuni NCTC 11168
Genome accession: NC_002163
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 365717 - 367222 bp
Length : 1506 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTTTGATAATATTTTAGAGCAGCAAAGAATAGAAAAAGCTAAGGAATTAAAAAATTTAGGGATCAATCCTTATCCTCA
TTTTTTAGAAAAAGAAATGTCTTTAAAGACTTTTAAGGATAAATTTTCTTATATTTTAGAGCAAGTTGAAAAAAGAGATG
AAAGTGTCAATGCTGTTGTTGCAGGACGTTTGAAACTTTTGCGTATAGCTGGGAAATCGATTTTTGCAAACATTGAAGAT
GAGGATACAAATTTACAAATTTATTTTAGTAAAGATAGCGTAGGCGAAGAGCTTTATACGATTTTAAAAAAGAATTTAGA
GGTGGGTGATATTGTTTTGGTTAAAGGTTTTCCTTTTGTAACTAAAACAGGTGAGTTTAGTTTACATGCAAGTGAAGTAA
AACTCGCTACAAAAGCTATTGTTCCTTTACCTGAAAAATATCATGGATTAACAGATATTGAGCAAAGATATCGTAAACGT
TATGTTGATATGATAATGAATGTCGAAGTTAGAAAAGATTTTTTAGTGCGTTCTAAAGTGGTGAGTTTAATCCGTCATTT
TTTTGAAAATAAAGGCTTTTTAGAAGTAGAAACTCCTATGATGCATCCGATTGCAGGTGGAGCAAACGCTAAGCCTTTTG
TAACTTTTCATAATTCTTTAGGCGTAGAAAGATTTTTAAGAATTGCTCCAGAACTTTATCTTAAAAGACTTATAGTAGGT
GGTTTTGAGGCGGTTTTTGAAATCAATCGTTGTTTTAGAAACGAAGGTATGGATTTAACTCATAATCCCGAATTTACAAC
TATAGAATTTTATTGGGCCTATCATAATTATAAAGATTTAATGGATTTAACCGAAGAACTTTTTGCTTTACTTTTGGATA
AACTTAATTTAGGAAAAACAATAGAATTTGATGGAAAAATGATAAATTTTTCTAAACCTTTTGAAAGAATAACCTATAAA
GACGCACTTTGTAAGTATGGTGGTTTAGATAGGGATTTAATCGAAGATAAGGAAAAAATTCTTACTAAATTAAAAGCAGA
TGGTTTTGAAGCGAATGAAAAGCTTGAACTTGGACATTTGCAAGCTGAACTTTTTGACAATTATGTGGAAGAAAAATTGA
TCAATCCTACTTTTGTGATTGATTTTCCTATTTCCATAAGTCCTTTATCAAGACGTAGCGATGAGGATTCTCAGATTGCT
GAGAGATTTGAGTTGTTTATTTGCGGAAGAGAATTGGCAAATGGTTTTAATGAGCTTAATGATCCTCTTGATCAATATGA
GAGATTTTTAAAACAAATTGAAGCTAAAAATGCAGGCGATGAAGAGGCTTGTGAAATGGATGAAGATTTTGTAAATGCTT
TGGGTTATGGAATGCCTCCAACGGCAGGGCAGGGCATAGGTATAGATAGACTTGTTATGCTTTTGACAAATAAAAAATCC
ATTCGTGATGTGATATTGTTTCCTGCAATGCGTCCATTAAAATCAGAACTAAAGGAGAAAGAATGA

Protein sequence :
MFDNILEQQRIEKAKELKNLGINPYPHFLEKEMSLKTFKDKFSYILEQVEKRDESVNAVVAGRLKLLRIAGKSIFANIED
EDTNLQIYFSKDSVGEELYTILKKNLEVGDIVLVKGFPFVTKTGEFSLHASEVKLATKAIVPLPEKYHGLTDIEQRYRKR
YVDMIMNVEVRKDFLVRSKVVSLIRHFFENKGFLEVETPMMHPIAGGANAKPFVTFHNSLGVERFLRIAPELYLKRLIVG
GFEAVFEINRCFRNEGMDLTHNPEFTTIEFYWAYHNYKDLMDLTEELFALLLDKLNLGKTIEFDGKMINFSKPFERITYK
DALCKYGGLDRDLIEDKEKILTKLKADGFEANEKLELGHLQAELFDNYVEEKLINPTFVIDFPISISPLSRRSDEDSQIA
ERFELFICGRELANGFNELNDPLDQYERFLKQIEAKNAGDEEACEMDEDFVNALGYGMPPTAGQGIGIDRLVMLLTNKKS
IRDVILFPAMRPLKSELKEKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 8e-105 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_002343838.1 lysyl-tRNA synthetase VFG1668 Protein 4e-105 47