Gene Information

Name : tkt (Cj1645)
Accession : YP_002345014.1
Strain : Campylobacter jejuni NCTC 11168
Genome accession: NC_002163
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1569190 - 1571088 bp
Length : 1899 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGAACATTCAAATTTTACAAGAACAGGCAAATACTCTAAGATTTTTAAGTGCTGATATGGTGCAAAAAGCAAACTCAGG
ACACCCAGGTGCACCTTTGGGCTTAGCAGATATTTTAAGTGTTTTAAGTTATCATTTAAAACACAATCCCAAAAATCCAA
CTTGGCTAAACCGAGATAGACTTGTATTTTCAGGCGGACATGCAAGTGCTTTGCTTTATAGTTTTTTACATTTAAGCGGC
TATGACTTAAGCTTAGAAGATCTTAAAAATTTCCGCCAACTTCATTCTAAAACCCCTGGACACCCTGAAATTTCAACTCT
TGGAGTAGAAATCGCTACAGGCCCTTTAGGACAAGGCGTTGCCAATGCTGTAGGCTTTGCTATGGCAGCAAAAAAAGCAC
AAAATTTGCTAGGCAGTGATTTAATCGATCATAAAATTTATTGTCTTTGCGGAGATGGGGATTTACAAGAAGGCATTTCT
TATGAAGCTTGTTCTTTAGCAGGACTTCACAAACTTGATAACTTCATACTTATTTATGATAGCAACAATATCTCTATAGA
AGGCGATGTAGGTTTAGCCTTTAACGAAAATGTAAAAATGCGTTTTGAAGCACAAGGATTTGAAGTTTTAAGTATAAATG
GACACGATTATGAAGAAATCAATAAAGCCTTAGAACAAGCTAAAAAATCCACAAAACCTTGTCTTATCATCGCAAAAACA
ACTATAGCAAAGGGTGCAGGAGAGCTTGAAGGCAGTCATAAAAGCCATGGCGCACCTTTGGGTGAAGAAGTGATTAAAAA
AGCCAAAGAACAAGCAGGCTTTGATCCAAATATCAGTTTTCATATCCCACAAGCAAGCAAAATCCGCTTTGAAAGTGCTG
TAGAACTTGGGGATTTAGAAGAAGCAAAATGGAAAGATAAGCTTGAAAAAAGTGCTAAAAAAGAACTTTTAGAAAGGCTA
TTAAATCCTGATTTTAACAAGATAGCTTATCCTGATTTTAAAGGAAAAGATCTTGCTACAAGAGATAGTAATGGTGAAAT
TTTAAATGTTTTAGCTAAAAATTTAGAAGGATTTTTAGGTGGAAGTGCAGACTTAGGCCCTTCGAATAAAACAGAACTTC
ACAGTATGGGAGACTTTGTAGAAGGTAAAAATATCCATTTTGGTATCAGAGAACACGCTATGGCAGCGATTAACAATGCT
TTTGCAAGATATGGAATTTTCTTACCATTTTCGGCAACTTTTTTCATCTTTAGCGAGTACTTAAAACCTGCCGCAAGAAT
AGCAGCTCTAATGAAAATCAAACATTTTTTCATTTTCACACACGATAGCATAGGCGTGGGCGAAGATGGACCAACACACC
AACCTATAGAACAACTTAGCACTTTTAGAGCTATGCCAAATTTTTTAACCTTTAGACCTGCTGATGGGGTGGAAAATGTC
AAAGCTTGGCAAATAGCCCTAAATGCTGATATTCCGAGTGCTTTTGTGCTTTCACGCCAAAAACTCAAAGCTCTAAATGA
ACCTGTTTTTGGAGATGTAAAAAACGGAGCGTATTTACTCAAAGAAAGCAAAGAGGCTAAATTTACACTTCTAGCAAGTG
GAAGTGAAGTTTGGCTTTGTCTAGAAAGTGCAAACGAACTTGAAAAACAAGGTTTTGCTTGTAATGTTGTTTCCATGCCT
TGTTTTGAACTTTTTGAAAAACAAGATAAAGCTTATCAAGAAAGATTGTTAAAAGGTGAAGTTATAGGTGTTGAAGCAGC
ACATTCTAATGAACTTTATAAATTTTGCCATAAAGTATATGGCATAGAAAGTTTTGGAGAAAGTGGTAAAGACAAAGATG
TGTTTGAACGCTTTGGATTTAGCGTTTCAAAGCTTGTAAATTTTATCCTTAGCAAATAA

Protein sequence :
MNIQILQEQANTLRFLSADMVQKANSGHPGAPLGLADILSVLSYHLKHNPKNPTWLNRDRLVFSGGHASALLYSFLHLSG
YDLSLEDLKNFRQLHSKTPGHPEISTLGVEIATGPLGQGVANAVGFAMAAKKAQNLLGSDLIDHKIYCLCGDGDLQEGIS
YEACSLAGLHKLDNFILIYDSNNISIEGDVGLAFNENVKMRFEAQGFEVLSINGHDYEEINKALEQAKKSTKPCLIIAKT
TIAKGAGELEGSHKSHGAPLGEEVIKKAKEQAGFDPNISFHIPQASKIRFESAVELGDLEEAKWKDKLEKSAKKELLERL
LNPDFNKIAYPDFKGKDLATRDSNGEILNVLAKNLEGFLGGSADLGPSNKTELHSMGDFVEGKNIHFGIREHAMAAINNA
FARYGIFLPFSATFFIFSEYLKPAARIAALMKIKHFFIFTHDSIGVGEDGPTHQPIEQLSTFRAMPNFLTFRPADGVENV
KAWQIALNADIPSAFVLSRQKLKALNEPVFGDVKNGAYLLKESKEAKFTLLASGSEVWLCLESANELEKQGFACNVVSMP
CFELFEKQDKAYQERLLKGEVIGVEAAHSNELYKFCHKVYGIESFGESGKDKDVFERFGFSVSKLVNFILSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 3e-110 43
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 6e-99 42