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Name : hsdM (Cj1553c) Accession : YP_002344925.1 Strain : Campylobacter jejuni NCTC 11168 Genome accession: NC_002163 Putative virulence/resistance : Unknown Product : type I restriction enzyme M protein Function : - COG functional category : V : Defense mechanisms COG ID : COG0286 EC number : 2.1.1.72 Position : 1487089 - 1488591 bp Length : 1503 bp Strand : - Note : Original (2000) note: Cj1553c, probable type I restriction enzyme M protein, len: 500 aa; simlar to many e.g. T1M1_ECOLI type I restriction enzyme EcoR124II M protein (EC 2.1.1.72) (520 aa), fasta scores; opt: 447 z-score: 527.4 E(): 4.7e-22, 25.9% identi DNA sequence : ATGGCAAAGAAAAAAGAAATAAAACTAGAAGATGCGTTATGGAAAAGTGCTGATAAATTACGCAAAAATATCGACGCAGC AGAGTATAAACACATAGTTTTAGGACTTATATTTTTACGCTACATTAGCGATAGCTTTATGCAAAAATACGAAGAGTTAT TAAAAGAACAAGATGATGGAGCCGACCCAGAAGATGCAGATGAATACCTAGCTGACAATATCTTCTTCGTTCCAGAAAAA TCTCGCTACAACTACATAAGAGATAACGCCAAAAATCCCAAAATAGGCAAAATGCTAGATGAAGCAATGGACGAGATAGA AAAACACAACGATACTCTAAAAGGAGTTTTGCCAAAAGTCTATGCCAAAGATAACTTAGATAGTAAATGCCTAGGCGAAC TTATAGATCTTATAGGAAATATCGCCTTTGACACTGGTAAAAGCACCGATGTTTTAGGTCATGTATTTGAGTATTTTTTA GGTGAATTTGCCCTAGCTGAAGGCAAACAAGGCGGACAATTCTACACTCCAAAATGCGTCGTAGAGCTCCTAGTAACTAT GCTTGAGCCATATAAAGGCAGAGTGTTTGATCCTTGCTGTGGAAGTGGCGGTATGTTTGTTCAAAGCGAAGAGTTTGTAA AATCTCACCAAGGCAGACTAGATGACATCTCAATCTATGGTCAAGAGTCAAATCAGACTACCTACAAACTCGCCAAAATG AACCTAGCCATAAGAAAAATCGAAAGCTCACAAGTGATATGGAACAACGAAGGCTCATTTTTAAACGACGCTCATAAAGA CTTAAAAGCCGATTTTATTATAGCCAATCCACCATTTAACGACTCGGACTGGAGCGGCGAACTGTTAGAAAACGATGGCA GATGGAAATACGGCGTCCCACCAGCAAGCAACGCCAACTACGCTTGGATACAGCACTTTTTATATCATCTATCACCAAAC GGCGGTGTAGCGGGATTTGTCCTAGCTAAAGGCGCACTTACAAGCAACACCACAAATGAAGCAGCCATTAGAAAAGCACT TATTGAAGATGATTTGATAGATTGTATAGTAAATCTACCCGCAAAGCTGTTTTTAAATACAGGTATTCCTGCATCACTTT GGTTTATAAGACGCCAAAAGCTACCAAAGACAGTCAAAAAAACGCTTTTTATAGATGCAAGAGATTTAGGAACTAGGATA AATAGACGCAACAAAACCCTAAACAAAGACGATATAAACCAAATCGCAAATATTTATAAAGCATGGAAAAACGGCACTGA TTATGAAGACATAAAAGGCTTTTGTAAAAGTGTTAGCATAGATGAGATAAGAGAGCTTTCTTATGTGCTTACCCCAGGGC GTTATGTGGGGCTTGCTGATAGTGATGATGAGTTTGATTTTGATACTAGATTTAACGAGCTTTTAGCAAAGTTAAAATCC CAAATCAAAACTGAGCAAGAGCTAAGTGAAATTATCTTAAAAAACTTAGAGAAGATTAAATGA Protein sequence : MAKKKEIKLEDALWKSADKLRKNIDAAEYKHIVLGLIFLRYISDSFMQKYEELLKEQDDGADPEDADEYLADNIFFVPEK SRYNYIRDNAKNPKIGKMLDEAMDEIEKHNDTLKGVLPKVYAKDNLDSKCLGELIDLIGNIAFDTGKSTDVLGHVFEYFL GEFALAEGKQGGQFYTPKCVVELLVTMLEPYKGRVFDPCCGSGGMFVQSEEFVKSHQGRLDDISIYGQESNQTTYKLAKM NLAIRKIESSQVIWNNEGSFLNDAHKDLKADFIIANPPFNDSDWSGELLENDGRWKYGVPPASNANYAWIQHFLYHLSPN GGVAGFVLAKGALTSNTTNEAAIRKALIEDDLIDCIVNLPAKLFLNTGIPASLWFIRRQKLPKTVKKTLFIDARDLGTRI NRRNKTLNKDDINQIANIYKAWKNGTDYEDIKGFCKSVSIDEIRELSYVLTPGRYVGLADSDDEFDFDTRFNELLAKLKS QIKTEQELSEIILKNLEKIK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hsdM | YP_251979.1 | type I restriction-modification system DNA methylase | Not tested | SCCmec | Protein | 5e-132 | 55 |
| hsdM | BAD24842.1 | HsdM protein | Not tested | Type-V SCCmec | Protein | 2e-131 | 55 |
| hsdM | BAH57701.1 | type I restriction-modification system DNA methylase | Not tested | Type-VII SCCmec | Protein | 3e-132 | 55 |
| api49 | CAF28523.1 | putative HsdM-like N-methyl transferase | Not tested | YAPI | Protein | 8e-103 | 42 |
