Gene Information

Name : guaA (Cj1248)
Accession : YP_002344639.1
Strain : Campylobacter jejuni NCTC 11168
Genome accession: NC_002163
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1176466 - 1178001 bp
Length : 1536 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAAAAAAGCAGATATTTTAGTTTTAGACTTTGGCTCTCAATACACTCAGCTTATAGCAAGACGCTTAAGGGAACAAGG
AGTTTATGCAGAAATTTTACCTTTTAATGTAAGCTTAGCTGATATTAAGGCAAAAGAACCAAAAGGTATTATTTTAAGCG
GAGGTCCAGCAAGTGTATATGCAACTGATGCGTATTTTTGCGATAAAGGTATATTTGACTTAAATCTACCTGTTCTTGGA
ATTTGTTATGGTATGCAGCTTATGGCACATCATTACAAAGCTACAGTAGCACCTGCAGGACATAAAGAATACGGCAAAGC
AAACATAGAAATTAAAAAAGATAACGCTTTGTTTAAAAATCTTCCAAAAAAACAAACCGTTTGGATGAGTCATTCTGATA
AAGTAGAAAATTTACCTCAAGGTTTTGAAGTTTTAGCCACAAGTGAAAATAGCCCTTTTTGTGTTTTTGGAAACGAAGAT
AAGAAATTCTTTGCTCTACAATTTCACCCAGAAGTACAACACAGCGAATTTGGCAAAAATATCTTAAAAAATTTTGCTAA
ATATGCTTGCAATTGTGAAAGTATTTGGAATATGGGTTCTTTTGCAAAAACTCAAGCAGAAAAAATCCGTGAAGAAGTAG
GCAATGATAAAGTGCTTTGTGCTGTAAGTGGCGGAGTAGATAGTAGCGTAGTTGCTGCACTTTTAGCTAGTGCTATAAAA
GAGCAAATTATAGTAGTTTTTGTAGATAATGGACTTTTAAGAAGTGGAGAAAAAGAACAAGTTGAATTTATGTTTAAAAA
CACTTTAGGCATCGATCTCATCAGCATTGATGCAAGTGAAATTTTCTTAAGTCGCTTAGTTAATGTCACAGATCCTGAAC
AAAAAAGAAAAATCATAGGAAATACCTTTATAGAAGTTTTTGAAGAAGAAGCAAAAAAACATAAAGATGTAAAATATCTT
GCTCAAGGCACACTTTATACTGATATCATAGAAAGTTCTGTTGTAGGTGCAAGCAAAACCATTAAAAGCCATCATAATGT
AGGGGGCTTACCTGAAAAAATGAATCTTAAACTCATAGAGCCTTTAAAAGAAATTTTTAAAGATGAAGTGCGTGCCTTAG
GACTTGAGCTTGGACTTAGCAAAGAAGTAGTTTATCGTCATCCTTTCCCTGGGCCAGGTCTTGCTATACGCATTATGGGA
GAAGTAAATCGCGCTAGCTTAGAACTATTACGCAAGGCTGATGTAATTTTACTTGAGGAACTTAAAAGTACAGGTTGGTA
TGATAAAACTTGGCAAGCATTTTGCGTACTTTTAAATGTTAAAAGCGTTGGAGTTATGGGGGATAACCGCACTTATGATA
ATGCAGTTTGTATACGCGTTGTAGATGCAAGTGATGGTATGACAGCTACCTTCTCGCATTTACCTTACGAAATTTTAGAA
AACATAAGTCGCCGTATCATCAATGAAGTAGAAGGTATAAATCGCGTTGTTTATGATATCTCAAGCAAACCACCTGCAAC
TATAGAATGGGAATAA

Protein sequence :
MKKADILVLDFGSQYTQLIARRLREQGVYAEILPFNVSLADIKAKEPKGIILSGGPASVYATDAYFCDKGIFDLNLPVLG
ICYGMQLMAHHYKATVAPAGHKEYGKANIEIKKDNALFKNLPKKQTVWMSHSDKVENLPQGFEVLATSENSPFCVFGNED
KKFFALQFHPEVQHSEFGKNILKNFAKYACNCESIWNMGSFAKTQAEKIREEVGNDKVLCAVSGGVDSSVVAALLASAIK
EQIIVVFVDNGLLRSGEKEQVEFMFKNTLGIDLISIDASEIFLSRLVNVTDPEQKRKIIGNTFIEVFEEEAKKHKDVKYL
AQGTLYTDIIESSVVGASKTIKSHHNVGGLPEKMNLKLIEPLKEIFKDEVRALGLELGLSKEVVYRHPFPGPGLAIRIMG
EVNRASLELLRKADVILLEELKSTGWYDKTWQAFCVLLNVKSVGVMGDNRTYDNAVCIRVVDASDGMTATFSHLPYEILE
NISRRIINEVEGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-136 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-136 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-136 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-116 48