Gene Information

Name : fliI (BB_0288)
Accession : NP_212422.1
Strain : Borrelia burgdorferi B31
Genome accession: NC_001318
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase FliI
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 297466 - 298776 bp
Length : 1311 bp
Strand : -
Note : identified by match to protein family HMM PF00006; match to protein family HMM PF02874; match to protein family HMM TIGR01026; match to protein family HMM TIGR03498

DNA sequence :
GTGAGCAATTTTTTTGAAAATTATTTAAGACAAGTAGATGATATTGAAACTGTTTCTTTTGTTGGCAGGGTGCAAAAAAT
AAAAGGTCTTTTAGTTGAGAGTTTAGGGCCTCAGTGCGCTATTGGAGATTTGTGTTTAATTGATCAAAGAAATGGCAAAA
AGGTATGCGCAGAGGTTTTAGGATTTAATGGTCCTTATGTTAGCCTTATGGCCTATGAAGGATTTAGCGGGATTGAAGTT
GGAAATAAAGTTTATTCTTTAAACAAAGGGCTAGAAATAAATCTTAGTGATGAGCTTTTGGGAAGAGTTATTGATTCTCT
TGGCAGACCTATTGATAATAAAGGGTCATTTTTGAACAATAGTTATAAAGAGTTAATTTTTGAAAAAATTAATCCAATTA
ATAGAAGTATTTTTGAAGATCAAATATTAACGGGAGTTAAAGTTCTTGATGGGTTTTTGCCAGTTGCAAAAGGACAAAGA
GTTGGTATTTTTTCTGGTTCTGGTGTTGGTAAATCTACTTTGCTTGGCATGATTGCAAAAAATTCAAATGCAGATGTAAA
TGTTATTGCTTTTATTGGGGAAAGGGGTCGAGAGCTTAATGAGTTTATTGAACATGAGCTTGGTGAAGAGCGTTTAAAAA
AAAGTGTTTTAGTTGTTTCAACTTCTGATGAATCTCCCATTTCAAGGTATAAGGGAGCTTATGTTGCTACCATGATAGCA
GAATACTTTAGGGAGCAAGGTAAAGATGTGGCTTTGCTTTTTGATTCTATTACTAGGTTTGCAAATGCTAAAAGAGAGAT
GTCTCTTTCTTTAGGAGAGCCTCCGGTAGCTAAAGGTTATCCGCCTTCTGTTTTTGTTGAAATTCCAATTTTGCTTGAGA
GATCGGGCTTTAATGGTAATGGGGGAAGTGTTACTGGGTTTTATACTGTTCTTGTTGAGGGGGATGATTTCACAGAGCCT
GTAGCCGATAATATTAAAGCTGTTTTGGATGGTCATATTATTTTAGACAGAGATTTGTTTGACAGGGGAATATATCCTTC
AATAAATGTTTTAAGTTCAACTTCAAGATCTATTCATAGAATAATGAGCCTAGAAAAACAAAAATTAATAATGAAAGCTA
GAAATTTATTGTCTATTTATAAAGATTATGAAGATCTTATTAGAACAGGAATTTATCTCAAAGGATCCAATAAGGATGTT
GATTTTGCAATTTCTAAGTATCCTAAGATTATTAATTTTATTTCTCAAGGAATAAACGAAACATTTGATTTTGAAAATTT
AGAAGATGAAATAAAGGAAATATTATCTTGA

Protein sequence :
MSNFFENYLRQVDDIETVSFVGRVQKIKGLLVESLGPQCAIGDLCLIDQRNGKKVCAEVLGFNGPYVSLMAYEGFSGIEV
GNKVYSLNKGLEINLSDELLGRVIDSLGRPIDNKGSFLNNSYKELIFEKINPINRSIFEDQILTGVKVLDGFLPVAKGQR
VGIFSGSGVGKSTLLGMIAKNSNADVNVIAFIGERGRELNEFIEHELGEERLKKSVLVVSTSDESPISRYKGAYVATMIA
EYFREQGKDVALLFDSITRFANAKREMSLSLGEPPVAKGYPPSVFVEIPILLERSGFNGNGGSVTGFYTVLVEGDDFTEP
VADNIKAVLDGHIILDRDLFDRGIYPSINVLSSTSRSIHRIMSLEKQKLIMKARNLLSIYKDYEDLIRTGIYLKGSNKDV
DFAISKYPKIINFISQGINETFDFENLEDEIKEILS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-77 43
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-80 43
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-80 43
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-81 43
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-80 43
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 4e-80 43
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-83 43
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 4e-83 43
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-84 42
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-84 42
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-83 42
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-75 42
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-84 41
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-84 41
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-83 41
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-84 41
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-70 41
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-70 41
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 4e-67 41
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-67 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI NP_212422.1 flagellum-specific ATP synthase FliI VFG2144 Protein 4e-95 46
fliI NP_212422.1 flagellum-specific ATP synthase FliI VFG0390 Protein 4e-82 44
fliI NP_212422.1 flagellum-specific ATP synthase FliI VFG2499 Protein 7e-79 44
fliI NP_212422.1 flagellum-specific ATP synthase FliI VFG0048 Protein 8e-82 43
fliI NP_212422.1 flagellum-specific ATP synthase FliI VFG0515 Protein 8e-81 43
fliI NP_212422.1 flagellum-specific ATP synthase FliI VFG1254 Protein 2e-83 42
fliI NP_212422.1 flagellum-specific ATP synthase FliI VFG0192 Protein 1e-81 41