Gene Information

Name : DR_0472 (DR_0472)
Accession : NP_294195.1
Strain :
Genome accession: NC_001263
Putative virulence/resistance : Resistance
Product : tetracycline-efflux transporter
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 472040 - 473263 bp
Length : 1224 bp
Strand : +
Note : similar to SP:P02982 percent identity: 62.82; identified by sequence similarity; putative

DNA sequence : 
GTGGGCCAGATGCCGCGTCGCCCGCCTGCCCTGCTCTTCATTTTGCTGACCGCCCTGATTGACGTGATGGGCATCGGCCT
CATCATTCCGGTGCTGCCGGGGCTGGTCAAGGAACTGGCGGGGTCCGAGGCCGGCGGAGCGCGCTTTATCGGCGTGCTGA
CGGCGGCTTACGCGGCGATGCAGTTCATCTTCGCGCCGATTCTGGGCACGCTCTCGGACCGCTTCGGGCGCCGCCCGGTG
CTGCTGCTCTCGCTGGCGGGGATGGTGCTCGATTACCTGCTGCTGTTTTTCTCGCCCAACCTGTGGTGGTTGCTGGTCGG
GCGGCTCATTGCCGGAGTTACCGGCGCCAGCCTGACCGTCGCCAACGCCTACATCGCCGACGTGACGGCTCCCGAGGACC
GCGCCAAGAACTTCGGGCGGCTGGGCGCCACCTGGGGTGTGGGGTTCATCCTGGGGCCGATGTTGGGCGGCTGGCTGGGC
GAACATGGGCTGCGGGCGCCGTTCCTGTTTGCCGCTGGGCTGACCGCCTTGAACTTTCTGTACGGCCTGCTGGTGCTGCC
CGAGTCGTTGCCGCCGGAAAAACGCGGCGCGGCGGGCGGCGGCACCCTCAATCCGTTTACGCCGCTGCGCGCACTGACCG
AATACCCGCTGCTGCGGGGGCTGACCCTGACCTTCGTGCTGCTGGGCCTCGCCGGGCAGGTCATCGTGAGCACCTGGGTG
CTGTACACCGAGGGCGTGCTGCGCTGGTCGCCGCTGCAAAACGGGATTGCCTTCGCGGTGTACGGCCTGCTGACGGCGGG
CGTGCAGGCGGGGCTGATTTCGCCCTTCATCGCCCGCTTCGGCGAACGGCGCACCATCATGACCGGGCTGGTGGCCTCCA
CCCTGGAATTCGTGGTGCTGAGCGTGGCCCGCAGCGCGCCGGTGCTGTATCTGTCGCTGGTGGTGGGGGCGCTGGGAGGG
CTCGCGCAGCCCGCCATGCAGGGCCTGATTTCGCGCCAGGTCGGCGAGCAGGAGCAGGGCCGCGTGATGGGGGCAATCAC
CAGCCTCAACAGCTTGGTGGGCGTCTTCGGGCCGCTGCTGGCGACGAGCGTGTTCGCTGCCGGCCAGGGCGCGGGCTTTC
CCGGCGCGGCGTTCGTGCTGGGCGCGGTGCTGTCTATTCTCGGCACCGTGCTTATTCTCAGCGTGCTGCGCGGGATTCCG
GGGACGGGGCGGGCGATGAAGTGA

Protein sequence : 
MGQMPRRPPALLFILLTALIDVMGIGLIIPVLPGLVKELAGSEAGGARFIGVLTAAYAAMQFIFAPILGTLSDRFGRRPV
LLLSLAGMVLDYLLLFFSPNLWWLLVGRLIAGVTGASLTVANAYIADVTAPEDRAKNFGRLGATWGVGFILGPMLGGWLG
EHGLRAPFLFAAGLTALNFLYGLLVLPESLPPEKRGAAGGGTLNPFTPLRALTEYPLLRGLTLTFVLLGLAGQVIVSTWV
LYTEGVLRWSPLQNGIAFAVYGLLTAGVQAGLISPFIARFGERRTIMTGLVASTLEFVVLSVARSAPVLYLSLVVGALGG
LAQPAMQGLISRQVGEQEQGRVMGAITSLNSLVGVFGPLLATSVFAAGQGAGFPGAAFVLGAVLSILGTVLILSVLRGIP
GTGRAMK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetA YP_006098396.1 tetracycline resistance protein Not tested Tn2411 Protein 2e-51 44
tetA(A) ACK44537.1 TetA(A) Not tested SGI1 Protein 2e-51 44
tetA(A) AGK07027.1 TetA(A) Not tested SGI1 Protein 2e-51 44
tetA(A) AGK07085.1 TetA(A) Not tested SGI1 Protein 2e-51 44
tetA CAJ77066.1 Tetracycline resistance protein Not tested AbaR1 Protein 1e-51 44
tetA(A) ACN81011.1 TetA(A) Not tested AbaR5 Protein 2e-51 44
tetA(G) AGK07104.1 TetA(G) Not tested SGI1 Protein 1e-41 42
tet(G) AAK02051.1 tetracycline resistance protein Not tested SGI1 Protein 1e-41 42
tetA(G) ABZ01843.1 TetA(G) Not tested SGI2 Protein 1e-41 42
tetA(G) AGK06974.1 TetA(G) Not tested SGI1 Protein 1e-41 42
tetA(B) AAL08445.1 tetracycline resistance protein TetA(B) Not tested SRL Protein 1e-44 42
tetA(B) AEZ06045.1 tetracycline efflux protein Not tested Tn6167 Protein 1e-44 42
tetB AEA34667.1 tetracycline resistance determinant Not tested Not named Protein 1e-44 42
tetA(B) AEQ20905.1 tetracycline resistance protein Not tested Tn6166 Protein 2e-44 42
BJAB07104_00277 YP_008207742.1 Permeases of the major facilitator superfamily Not tested AbaR25 Protein 2e-44 42
BJAB0868_00281 YP_008211607.1 Permeases of the major facilitator superfamily Not tested AbaR26 Protein 2e-44 42
ABZJ_00260 YP_005524216.1 Tetracycline resistance protein, class B (TETA(B) ) (Metal-tetracycline/H(+) antiporter) Not tested AbaR22 Protein 2e-44 42
tetA(B) AFH57202.1 tetracycline resistance protein Not tested AbaR4a Protein 1e-44 42
tetA CAJ77034.1 Tetracycline resistance protein Not tested AbaR1 Protein 5e-43 41
tetA YP_005797160.1 tetracycline resistance protein, class G (TETA(G)) Not tested AbaR4e Protein 2e-44 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
DR_0472 NP_294195.1 tetracycline-efflux transporter AY264780.2.gene3.p01 Protein 2e-62 48
DR_0472 NP_294195.1 tetracycline-efflux transporter AF090987.gene.p01 Protein 3e-47 44
DR_0472 NP_294195.1 tetracycline-efflux transporter AY743590.gene.p01 Protein 7e-55 44
DR_0472 NP_294195.1 tetracycline-efflux transporter NC_010410.6002597.p0 Protein 9e-52 44
DR_0472 NP_294195.1 tetracycline-efflux transporter CP001485.1.gene2821. Protein 9e-52 44
DR_0472 NP_294195.1 tetracycline-efflux transporter AF534183.gene.p01 Protein 8e-52 44
DR_0472 NP_294195.1 tetracycline-efflux transporter Y19114.gene.p01 Protein 4e-51 43
DR_0472 NP_294195.1 tetracycline-efflux transporter X75761.gene.p01 Protein 9e-51 43
DR_0472 NP_294195.1 tetracycline-efflux transporter NC_011586.7045189.p0 Protein 2e-47 43
DR_0472 NP_294195.1 tetracycline-efflux transporter NC_009085.4918440.p0 Protein 1e-42 42
DR_0472 NP_294195.1 tetracycline-efflux transporter Y19116.gene.p01 Protein 2e-42 42
DR_0472 NP_294195.1 tetracycline-efflux transporter NC_010558.1.6275971. Protein 8e-45 42
DR_0472 NP_294195.1 tetracycline-efflux transporter AB084246.gene.p01 Protein 3e-45 42
DR_0472 NP_294195.1 tetracycline-efflux transporter NC_010410.6002612.p0 Protein 3e-43 41
DR_0472 NP_294195.1 tetracycline-efflux transporter AF133140.gene.p01 Protein 3e-43 41
DR_0472 NP_294195.1 tetracycline-efflux transporter NC_011586.7043399.p0 Protein 4e-43 41
DR_0472 NP_294195.1 tetracycline-efflux transporter AF121000.gene.p01 Protein 1e-50 41
DR_0472 NP_294195.1 tetracycline-efflux transporter NC_011595.7059241.p0 Protein 5e-43 41
DR_0472 NP_294195.1 tetracycline-efflux transporter AJ420072.gene.p01 Protein 7e-49 41
DR_0472 NP_294195.1 tetracycline-efflux transporter NC_010410.6003291.p0 Protein 4e-43 41
DR_0472 NP_294195.1 tetracycline-efflux transporter L06940.gene.p01 Protein 2e-42 41
DR_0472 NP_294195.1 tetracycline-efflux transporter V00611.gene.p01 Protein 1e-44 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
DR_0472 NP_294195.1 tetracycline-efflux transporter VFG1036 Protein 7e-45 42