Gene Information

Name : DR_1276 (DR_1276)
Accession : NP_295000.1
Strain :
Genome accession: NC_001263
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1281986 - 1283263 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTGGACCTGAAATTTATCCGTGAGAACCCCGACGCCGTGCGCGAGGCCATTCGCGTCAAGAACGTGGCCCTTGACCT
GGATGACCTGTTGCAGCGTGACCGCGACCTCGTGGCGCTCAAGCAGCGCGTGGAAGCCATGCAGACCGAGCGCAATGCCA
ACGCCAAGCTGGTGCCCAAGGCCAGCCCCGAGGACCGCCCCGGCCTGATTCAAAAGGGCAAGGACCTGAGCGAAGACCTC
AAGGCGCTCGAGCCCCAACTGCGCGAGCAGGAAGACGCCCTGAAGCAACTGCTGCTGCGCGTGCCCAACATTCCGCTGCC
GGGCGTGCCCGTCGGCAAGGACGAAGACGACAACGTGGAACTGCGCCGCGAAGGCGAGCTGCCTGGGTTCGACTTCACGC
CGCTCGACCAGGTCGAGATTCTGGAAAAGCAGGGCTGGGCCGACTTCGAGCGTGTCGCCCGCGTCTCGGGCAGCCGCAGC
TACCTGCTCAAGGGCGACGCGGCGCTGCTGGAAATGGCGGTGCTGATGTTCGCGCTCGATTTCCTGTCGCAGCGCGGCTT
TACTCCACTTTCGACCACGGCGCTCGTCCGCCGCGAAACGCTGGTCAACTCGGGCCATTTCCCCGGCGACGAGGAATCGG
TCTACAAGCTTGAAGGCGATGAACTGCTGCTCGCTGGAACCGCCGAGGTGCCGATCAATAGCCTCTACGCGGGCGAGCAG
CTCAGCGCCGACGAGTTGCCGCTGACCTTCGCGGGTTTCAGCGCCGCCTTCCGCCGCGAGGCCGGGAGCGCCGGGCGCGA
CGTGCGCGGGCTGATTCGCGTCCACGAGTTCCGCAAGGTCGAGCAGTACGTCCTGTGCCGCGCCGACCAGGAAGAGGGCC
TGAAATGGTTCGAGCGCCTGCTGAGCAACGCCGAGGGGCTGTTGCAGGCACTGGAGCTGCCCTACCGCGTCATTCAGAAC
TGCACTGGCGACATGGGCGCGGGCAAGGTGCTGATGTACGACATCGAAACCTGGGTGCCGAGCGAGCAGAAGTACCGCGA
AACCCACTCCTGCTCGTACCTGGGCGACTGGCAGGCCCGCCGCACCGGCCTGCGCTACCGCGACGAGCACGGCAAGCTGC
TCTACGCCCACACCCTCAACAACACCGGCATCGCCAGCCCGCGCATTCTGGTGCCGCTGCTCGAAAACCACCAGCAGGCT
GACGGCACCGTGCGCGTGCCCGCCGCGCTGCGCCCTTACCTCGGCGGCAGGGAAGTGCTGGGCCAGCCGGTGCGCTGA

Protein sequence :
MLDLKFIRENPDAVREAIRVKNVALDLDDLLQRDRDLVALKQRVEAMQTERNANAKLVPKASPEDRPGLIQKGKDLSEDL
KALEPQLREQEDALKQLLLRVPNIPLPGVPVGKDEDDNVELRREGELPGFDFTPLDQVEILEKQGWADFERVARVSGSRS
YLLKGDAALLEMAVLMFALDFLSQRGFTPLSTTALVRRETLVNSGHFPGDEESVYKLEGDELLLAGTAEVPINSLYAGEQ
LSADELPLTFAGFSAAFRREAGSAGRDVRGLIRVHEFRKVEQYVLCRADQEEGLKWFERLLSNAEGLLQALELPYRVIQN
CTGDMGAGKVLMYDIETWVPSEQKYRETHSCSYLGDWQARRTGLRYRDEHGKLLYAHTLNNTGIASPRILVPLLENHQQA
DGTVRVPAALRPYLGGREVLGQPVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-67 42