Gene Information

Name : secA (BSU35300)
Accession : NP_391410.1
Strain : Bacillus subtilis 168
Genome accession: NC_000964
Putative virulence/resistance : Unknown
Product : protein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 3628310 - 3630835 bp
Length : 2526 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGCTTGGAATTTTAAATAAAATGTTTGATCCAACAAAACGTACGCTGAATAGATACGAAAAAATTGCTAACGATATTGA
TGCGATTCGCGGAGACTATGAAAATCTCTCTGACGACGCATTGAAACATAAAACAATTGAATTTAAAGAGCGTCTTGAAA
AAGGGGCGACAACGGATGATCTTCTTGTTGAAGCTTTCGCTGTTGTTCGAGAAGCTTCACGCCGCGTAACAGGCATGTTT
CCGTTTAAAGTCCAGCTCATGGGGGGCGTGGCGCTTCATGACGGAAATATAGCGGAAATGAAAACAGGGGAAGGGAAAAC
ATTAACGTCTACCCTGCCTGTTTATTTAAATGCGTTAACCGGTAAAGGCGTACACGTCGTGACTGTCAACGAATACTTGG
CAAGCCGTGACGCTGAGCAAATGGGGAAAATTTTCGAGTTTCTCGGTTTGACTGTCGGTTTGAATTTAAACTCAATGTCA
AAAGACGAAAAACGGGAAGCTTATGCCGCTGATATTACTTACTCCACAAACAACGAGCTTGGCTTCGACTATTTGCGTGA
CAATATGGTTCTTTATAAAGAGCAGATGGTTCAGCGCCCGCTTCATTTTGCGGTAATAGATGAAGTTGACTCTATTTTAA
TTGATGAAGCAAGAACACCGCTTATCATTTCTGGACAAGCTGCAAAATCCACTAAGCTGTACGTACAGGCAAATGCTTTT
GTCCGCACGTTAAAAGCGGAGAAGGATTACACGTACGATATCAAAACAAAAGCTGTACAGCTTACTGAAGAAGGAATGAC
GAAGGCGGAAAAAGCATTCGGCATCGATAACCTCTTTGATGTGAAGCATGTCGCGCTCAACCACCATATCAACCAGGCCT
TAAAAGCTCACGTTGCGATGCAAAAGGACGTTGACTATGTAGTGGAAGACGGACAGGTTGTTATTGTTGATTCCTTCACG
GGACGTCTGATGAAAGGCCGCCGCTACAGTGAGGGGCTTCACCAAGCGATTGAAGCAAAGGAAGGGCTTGAGATTCAAAA
CGAAAGCATGACCTTGGCGACGATTACGTTCCAAAACTACTTCCGAATGTACGAAAAACTTGCCGGTATGACGGGTACAG
CTAAGACAGAGGAAGAAGAATTCCGCAACATCTACAACATGCAGGTTGTCACGATCCCTACCAACAGGCCTGTTGTCCGT
GATGACCGCCCGGATTTAATTTACCGCACGATGGAAGGAAAGTTTAAGGCAGTTGCGGAGGATGTCGCACAGCGTTACAT
GACGGGACAGCCTGTTCTAGTCGGTACGGTTGCCGTTGAAACATCTGAATTGATTTCTAAGCTGCTTAAAAACAAAGGAA
TTCCGCATCAAGTGTTAAATGCCAAAAACCATGAACGTGAAGCGCAGATCATTGAAGAGGCCGGCCAAAAAGGCGCAGTT
ACGATTGCGACTAACATGGCGGGGCGCGGAACGGACATTAAGCTTGGCGAAGGTGTAAAAGAGCTTGGCGGGCTCGCTGT
AGTCGGAACAGAACGACATGAATCACGCCGGATTGACAATCAGCTTCGAGGTCGTTCCGGACGTCAGGGAGACCCGGGGA
TTACTCAATTTTATCTTTCTATGGAAGATGAATTGATGCGCAGATTCGGAGCTGAGCGGACAATGGCGATGCTTGACCGC
TTCGGCATGGACGACTCTACTCCAATCCAAAGCAAAATGGTATCTCGCGCGGTTGAATCGTCTCAAAAACGCGTCGAAGG
CAATAACTTCGATTCGCGTAAACAGCTTCTGCAATATGATGATGTTCTCCGCCAGCAGCGTGAGGTCATTTATAAGCAGC
GCTTTGAAGTCATTGACTCTGAAAACCTGCGTGAAATCGTTGAAAATATGATCAAGTCTTCTCTCGAACGCGCAATTGCA
GCCTATACGCCAAGAGAAGAGCTTCCTGAGGAGTGGAAGCTTGACGGTCTAGTTGATCTTATCAACACAACTTATCTTGA
TGAAGGTGCACTTGAGAAGAGCGATATCTTCGGCAAAGAACCGGATGAAATGCTTGAGCTCATTATGGATCGCATCATCA
CAAAATATAATGAGAAGGAAGAGCAATTCGGCAAAGAGCAAATGCGCGAATTCGAAAAAGTTATCGTTCTTCGTGCCGTT
GATTCTAAATGGATGGATCATATTGATGCGATGGATCAGCTCCGCCAAGGGATTCACCTTCGTGCTTACGCGCAGACGAA
CCCGCTTCGTGAGTATCAAATGGAAGGTTTTGCGATGTTTGAGCATATGATTGAATCAATTGAGGACGAAGTCGCAAAAT
TTGTGATGAAAGCTGAGATTGAAAACAATCTGGAGCGTGAAGAGGTTGTACAAGGTCAAACAACAGCTCATCAGCCGCAA
GAAGGCGACGATAACAAAAAAGCAAAGAAAGCACCGGTTCGCAAAGTGGTTGATATCGGACGAAATGCCCCATGCCACTG
CGGAAGCGGGAAAAAATATAAAAATTGCTGCGGCCGTACTGAATAG

Protein sequence :
MLGILNKMFDPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDDLLVEAFAVVREASRRVTGMF
PFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMS
KDEKREAYAADITYSTNNELGFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAF
VRTLKAEKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAMQKDVDYVVEDGQVVIVDSFT
GRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVR
DDRPDLIYRTMEGKFKAVAEDVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAV
TIATNMAGRGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDELMRRFGAERTMAMLDR
FGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYDDVLRQQREVIYKQRFEVIDSENLREIVENMIKSSLERAIA
AYTPREELPEEWKLDGLVDLINTTYLDEGALEKSDIFGKEPDEMLELIMDRIITKYNEKEEQFGKEQMREFEKVIVLRAV
DSKWMDHIDAMDQLRQGIHLRAYAQTNPLREYQMEGFAMFEHMIESIEDEVAKFVMKAEIENNLEREEVVQGQTTAHQPQ
EGDDNKKAKKAPVRKVVDIGRNAPCHCGSGKKYKNCCGRTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 2e-131 42