Gene Information

Name : leuS (BSU30320)
Accession : NP_390910.1
Strain : Bacillus subtilis 168
Genome accession: NC_000964
Putative virulence/resistance : Unknown
Product : leucine--tRNA ligase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 3102629 - 3105043 bp
Length : 2415 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
TTGAGTTTTCAGCACAAAGAGATAGAAAAGAAATGGCAGACATATTGGCTTGAAAACAAAACATTTGCCACTCTTGATAA
TAATGAAAAACAAAAATTTTACGCGCTGGACATGTTTCCTTATCCGTCTGGAGCTGGGTTGCACGTCGGCCATCCTGAAG
GATACACAGCTACGGATATTCTGTCCCGCATGAAGCGCATGCAGGGCTATGATGTCCTTCATCCAATGGGCTGGGACGCA
TTCGGCCTGCCAGCTGAACAGTACGCGCTTGACACAGGGAACGACCCCGCTGTGTTTACGAAGCAGAATATTGATAACTT
CCGCCGCCAAATTCAAGCGCTTGGCTTCTCATATGACTGGGATCGCGAAATCAATACGACTGACCCTGAATACTATAAAT
GGACGCAATGGATTTTCTTAAAGCTATACGAAAAAGGCCTTGCTTACGTTGACGAAGTGCCTGTAAACTGGTGCCCTGCG
CTCGGTACTGTTCTTGCCAACGAAGAAGTCATTGACGGCAAGAGCGAACGCGGCGGCCATCCGGTAGAGAGACGCCCAAT
GAAGCAGTGGATGCTGAAAATCACCGCTTATGCGGACAGGCTCCTTGAGGACTTGGAAGAGCTTGATTGGCCGGAAAGCA
TTAAAGATATGCAGCGCAACTGGATCGGCCGTTCGGAAGGCGCTCACGTTCATTTTGCTATAGATGGACATGATGATTCC
TTTACAGTGTTTACAACAAGACCAGATACGCTGTTTGGCGCTACATACACTGTCCTTGCCCCGGAACACGCATTGGTGGA
AAACATCACAACGGCAGAGCAAAAAGAAGCTGTTGAAGCTTATATCAAAGAAATTCAATCAAAGAGTGACCTAGAACGCA
CAGATCTTGCGAAAACAAAGACAGGCGTATTTACAGGAGCGTATGCGATCAATCCTGTAAACGGAGAAAAACTGCCGATT
TGGATTGCGGATTATGTTCTTGCATCATACGGAACAGGTGCTGTCATGGCAGTTCCAGGACACGATGAGCGTGATTTTGA
ATTCGCCAAAACATTCGGCCTTCCGGTGAAGGAAGTCGTAAAAGGCGGGAACGTTGAGGAAGCAGCCTATACTGGCGACG
GCGAGCACGTGAACTCTGATTTCCTGAACGGCCTTCACAAACAGGAAGCGATTGAAAAAGTGATCGCTTGGCTGGAAGAA
ACGAAAAACGGTGAGAAGAAAGTGACGTACCGTCTTCGTGACTGGCTCTTCAGCCGCCAGCGTTATTGGGGCGAGCCGAT
TCCGGTCATTCATTGGGAAGACGGAACGTCAACAGCTGTCCCGGAAGAGGAGCTGCCGCTGATTTTGCCAAAAACGGATG
AAATCAAACCGAGCGGAACGGGCGAATCACCGCTTGCGAACATTAAAGAGTGGGTGGAAGTCACAGACCCTGAGACAGGG
AAAAAAGGAAGAAGAGAAACGAATACAATGCCGCAATGGGCGGGAAGCTGCTGGTATTTCTTGCGCTATATTGATCCGCA
CAATCCGGATCAGCTGGCATCACCAGAAAAATTGGAAAAATGGCTTCCGGTCGATATGTATATCGGCGGTGCAGAACATG
CCGTGCTTCACCTTCTGTATGCCCGCTTCTGGCATAAGTTCCTTTATGATATCGGCGTAGTGCCGACGAAAGAACCGTTC
CAAAAGCTGTACAACCAAGGAATGATTCTCGGCGAAAACAACGAAAAAATGAGTAAATCTAAAGGGAACGTTGTCAATCC
TGACGAAATCGTGGCCTCTCACGGTGCTGATACGCTGAGATTGTACGAAATGTTCATGGGACCTCTTGATGCTTCAATCG
CCTGGTCTGAATCAGGATTAGACGGTGCGCGCCGTTTCCTTGACCGTGTATGGCGCCTATTTATTGAAGACAGCGGTGAG
CTTAATGGAAAAATCGTTGAAGGCGCGGGTGAAACATTGGAGCGCGTCTATCATGAAACGGTCATGAAAGTCACAGACCA
TTATGAAGGCCTTCGTTTCAACACGGGTATTTCCCAGCTGATGGTCTTTATTAATGAAGCTTATAAAGCAACAGAACTGC
CGAAAGAATATATGGAAGGCTTCGTGAAGCTTCTTTCTCCTGTCGCGCCACACTTAGCGGAAGAGCTATGGGAGAAGCTT
GGCCATTCCGGCACAATTGCCTACGAAGCTTGGCCTGTATATGATGAAACAAAACTTGTGGATGATGAAGTTGAAATCGT
TGTTCAGCTGAACGGAAAAGTAAAAGCGAAATTACAGGTTCCTGCCGATGCAACGAAAGAACAGCTGGAACAGCTTGCTC
AAGCAGATGAAAAGGTCAAAGAGCAGCTTGAAGGCAAAACGATTCGGAAAATCATCGCGGTGCCTGGGAAGCTTGTCAAT
ATTGTGGCAAACTAA

Protein sequence :
MSFQHKEIEKKWQTYWLENKTFATLDNNEKQKFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGYDVLHPMGWDA
FGLPAEQYALDTGNDPAVFTKQNIDNFRRQIQALGFSYDWDREINTTDPEYYKWTQWIFLKLYEKGLAYVDEVPVNWCPA
LGTVLANEEVIDGKSERGGHPVERRPMKQWMLKITAYADRLLEDLEELDWPESIKDMQRNWIGRSEGAHVHFAIDGHDDS
FTVFTTRPDTLFGATYTVLAPEHALVENITTAEQKEAVEAYIKEIQSKSDLERTDLAKTKTGVFTGAYAINPVNGEKLPI
WIADYVLASYGTGAVMAVPGHDERDFEFAKTFGLPVKEVVKGGNVEEAAYTGDGEHVNSDFLNGLHKQEAIEKVIAWLEE
TKNGEKKVTYRLRDWLFSRQRYWGEPIPVIHWEDGTSTAVPEEELPLILPKTDEIKPSGTGESPLANIKEWVEVTDPETG
KKGRRETNTMPQWAGSCWYFLRYIDPHNPDQLASPEKLEKWLPVDMYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPF
QKLYNQGMILGENNEKMSKSKGNVVNPDEIVASHGADTLRLYEMFMGPLDASIAWSESGLDGARRFLDRVWRLFIEDSGE
LNGKIVEGAGETLERVYHETVMKVTDHYEGLRFNTGISQLMVFINEAYKATELPKEYMEGFVKLLSPVAPHLAEELWEKL
GHSGTIAYEAWPVYDETKLVDDEVEIVVQLNGKVKAKLQVPADATKEQLEQLAQADEKVKEQLEGKTIRKIIAVPGKLVN
IVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 68