Gene Information

Name : hemC (BSU28150)
Accession : NP_390693.1
Strain : Bacillus subtilis 168
Genome accession: NC_000964
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2875951 - 2876895 bp
Length : 945 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGATGAGAACGATTAAAGTAGGTTCCAGACGGAGCAAACTCGCTATGACTCAAACAAAATGGGTTATTCAAAAACTGAA
GGAAATCAATCCTTCGTTTGCTTTTGAAATTAAAGAGATCGTGACAAAGGGCGACCGGATTGTCGATGTTACACTCTCAA
AAGTGGGTGGAAAAGGGCTTTTTGTCAAAGAAATTGAACAGGCGCTTTTAAACGAAGAGATTGATATGGCAGTGCACAGC
ATGAAGGACATGCCTGCTGTTTTGCCTGAAGGCCTTGTGATCGGCTGTATTCCTGAACGGGAGGACCCGCGTGATGCCCT
TATTTCAAAGAATCGCGTAAAGCTTTCAGAAATGAAGAAAGGTGCTGTCATTGGCACAAGCAGTTTAAGAAGAAGCGCGC
AGCTTTTGATTGAGCGCCCTGACCTTACAATTAAATGGATTAGAGGTAATATAGATACAAGACTTCAAAAGCTGGAAACA
GAGGATTATGACGCAATTATTTTAGCGGCTGCCGGCCTTTCCAGAATGGGTTGGAAGCAAGATGTCGTAACCGAATTCCT
TGAGCCTGAGCGCTGTTTGCCTGCTGTGGGGCAGGGAGCCCTGGCGATTGAGTGCCGAGAATCGGATGAAGAGCTGTTGG
CGTTGTTTTCTCAGTTTACAGATGAATATACAAAACGGACTGTCTTAGCGGAACGTGCTTTTTTAAACGCGATGGAGGGC
GGCTGCCAGGTTCCGATCGCGGGCTACTCCGTGTTAAATGGACAGGATGAAATTGAAATGACAGGTCTTGTCGCTTCACC
TGACGGCAAAATCATTTTTAAAGAAACCGTCACCGGAAACGATCCGGAGGAAGTAGGAAAGCGCTGTGCCGCTCTTATGG
CTGACAAAGGAGCAAAAGATTTAATTGATCGTGTAAAACGGGAGCTTGACGAGGATGGAAAATGA

Protein sequence :
MMRTIKVGSRRSKLAMTQTKWVIQKLKEINPSFAFEIKEIVTKGDRIVDVTLSKVGGKGLFVKEIEQALLNEEIDMAVHS
MKDMPAVLPEGLVIGCIPEREDPRDALISKNRVKLSEMKKGAVIGTSSLRRSAQLLIERPDLTIKWIRGNIDTRLQKLET
EDYDAIILAAAGLSRMGWKQDVVTEFLEPERCLPAVGQGALAIECRESDEELLALFSQFTDEYTKRTVLAERAFLNAMEG
GCQVPIAGYSVLNGQDEIEMTGLVASPDGKIIFKETVTGNDPEEVGKRCAALMADKGAKDLIDRVKRELDEDGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-59 48
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-59 48