Gene Information

Name : dfrA (BSU21810)
Accession : NP_390064.1
Strain : Bacillus subtilis 168
Genome accession: NC_000964
Putative virulence/resistance : Unknown
Product : dihydrofolate reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : 1.5.1.3
Position : 2296603 - 2297109 bp
Length : 507 bp
Strand : -
Note : Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10574451, 12682299, 2840350, 3918568; Product type e: enzyme

DNA sequence :
ATGATTTCATTCATTTTTGCGATGGATGCCAACAGGCTTATCGGCAAAGACAATGATTTGCCGTGGCATTTGCCCAATGA
TCTTGCATACTTTAAGAAAATAACATCGGGCCATTCAATCATTATGGGCCGGAAAACATTTGAATCGATCGGACGTCCGC
TTCCAAATCGGAAAAATATTGTCGTTACCTCAGCGCCGGATTCAGAATTTCAGGGATGCACGGTTGTCAGTTCATTAAAG
GATGTACTGGACATTTGTTCAGGCCCTGAAGAATGCTTTGTGATCGGAGGGGCTCAGCTCTATACGGACCTGTTCCCTTA
TGCGGACAGACTGTATATGACGAAAATTCATCACGAGTTTGAGGGTGACCGTCACTTTCCTGAATTTGATGAATCCAATT
GGAAGCTGGTTTCTTCTGAGCAGGGGACCAAAGACGAAAAAAACCCGTATGATTACGAATTTCTAATGTATGAAAAAAAG
AATTCTTCTAAAGCGGGAGGATTTTAA

Protein sequence :
MISFIFAMDANRLIGKDNDLPWHLPNDLAYFKKITSGHSIIMGRKTFESIGRPLPNRKNIVVTSAPDSEFQGCTVVSSLK
DVLDICSGPEECFVIGGAQLYTDLFPYADRLYMTKIHHEFEGDRHFPEFDESNWKLVSSEQGTKDEKNPYDYEFLMYEKK
NSSKAGGF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
folA-2 YP_189146.1 dihydrofolate reductase Not tested ¥ÕSP¥â Protein 7e-28 41