Gene Information

Name : nrdEB (BSU20060)
Accession : NP_389888.2
Strain : Bacillus subtilis 168
Genome accession: NC_000964
Putative virulence/resistance : Unknown
Product : ribonucleoside-diphosphate reductase NrdEB subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 2162108 - 2165614 bp
Length : 3507 bp
Strand : -
Note : Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11470879, 16621400, 17395719, 9465078; Product type e: enzyme

DNA sequence :
TTGACAAACACAATACCAAATTGGATCAAGCTCAATAATGAAATCATGATCCAGAAAGATGGGAAGTATCAATTTGAAAA
GGATAAGGAGGCCGTACATAGTTACTTTGTTGATTACATAAATCAAAACACAGTCTTTTTCCATGATCTGAAAGAGAAGC
TGGACTATCTGATTAAAAATGATTATTACGAGGAAGAATTCTTAAGCAAATATACATTCGAACAGATTAAATCAATCTAT
AAGATTGCTTACAGTTACAAATTCAGATTCCCTTCTTTTATGAGTGCCTTTAAGTTCTACAATGACTACGCATTGAAGAC
AAACGATAAAACAAAGATCCTGGAAAGGTATGAGGATCGTGTCTCAATTGTGGCTTTATATTGCGCTGATGGCGATTACG
AGAAGGCTGTTGAGGAAGTACATACTATGATGAAACAAGAGTATCAGCCAGCAACACCTACTTTCCTTAATGCTGGACGT
AAGCGAAGAGGTGAAATGGTGAGCTGCTTCTTACTTGAAGTAGGCGACAGTTTGAATGATATTTCACGTGCTATTGATAT
TTCCATGCAGCTTTCTAAGCTAGGTGGAGGAGTAGCATTAAATCTAAACAAACTAAGAGCCAAAGGTGAAGCGATTAAAG
ACGTAGAGAATGCGACTAAAGGTGTCGTAGGTGTTATGAAACTTCTAGATAATGCCTTCAGATATGCCGACCAAATGGGT
TGATTTGGCCCCTTTCATCAGCAATGGTGATCGAAAACCTCTTTAATTCATGGGAACTCCTACAGGGACAATCATGAGCG
AAGCAAGACTAAGTCTTGAACGTGCAACGACTAGCCGAAAGGCGTAGGCTGCAAGCTATTGGCAGTCGAAACAGGAGGCA
CCCTTAGAGGGTGAAGATATAGTCTAACCTTCATGGTAACATGAAGCAGCCATATGGCGGGACGTGCTTAGCGAACACGT
TTGAATGGTCTGCAAAGACAAGGATCAGGAGCAGTTTATCTAAGTGTATTCCATCCAGACATTACAGACTTCCTGGATAC
CAAAAAAATAAGTGCTGATGAAGATGTCCGAGTTAAAACACTGTCTATTGGCGTAGTTGTTCCAGACAAATTTATTGAAT
TGGCAAGGGAAGACAAGGATTATTACATGTTCTATCCGCATTCAGTATACAAGGAGTATGGGCAGTATCTAGATGAGCTA
GACATTAATGAAATGTATGATGAGCTTGTTGAAAATCCAAGAGTTAGAAAAGCAAAGGGAAATGCTCGAAAGTTGTTGGA
GCAATTGGCTATTCTAAGAAGCGAATCTGGCTATCCGTATATTATGTTCGCTGACAATGTAAATAAAGTGCATCCAAATG
AACATATTTCAAAAGTGAAGTTTTCAAATTTGTGCGTTACTGGAGAAACACTTCTTTTAACTGAGAATGGATATGAAAAA
GCAGCCGATCTTTATAAAAAGCAGAATGATCTTAAAGTGGTCATTGATAATAGAACAAAAGATTTTGCAGTTGGTAGCAA
AGGTACCACAATTGTAGATGCAATTCCAATGCAACTGACTAAAAAAGATGCGGAAATATTTAAAGTCAAAACGAAGCAAG
GATATGAAATTAGGGCAACTGAGTGGCACAAATTCTATGTGAAAAGAGATGGTGAAATTCAAAAGCTCCAATTGAATCAA
CTGAAAACAGGCGATAAATTATTAGTCCAATCAGCTGAAGGAGCATACGGGAAAATTCATGAACCCGATCTTGCATACAT
TATGGGCATTATAGCTGGTGATGGAACCATTACTGAAAAAACTGCCAAGATTTATTTATACGATAATAAAAAAGTTCTTG
AGCAGAAAGTTACTGATGCAGTTCACCGTATTATTCAAAAACACAAGGTTGATCGTGCTTATAAGCACAATACATCACTT
CTCCCAACATTTAATATGGCCAACCCAGAAAAACAAGATTTGCTCTACATGAATAGTACTGTCTTATTTGACATCTTGAA
GAAGTTCGGTATGAACAAAGAAACAAAAACAAGAGTCCCAGAATTCATTTTTCAAGCTAATAAGGAAACGCAAGCAGCTT
ATTTATCGGGTTTATTCCAGACTGATGGGTGTGTAAATGCAAATCATAAAGCCAAAGCATTAACTATTGAGTTAACATCC
ATCCACTATGAGAGCCTTCAGGACGTTCAGAAGCTGTTACTGAACATGGGTGTTTATACAACGATTTATTCTAACAACAA
GCGCTCACAAGAACTCCTTCCTGATGGAAAAGGTGGTTCTAAGCTTTACAATGTAAAACCAACACACAAAATCAGTATTC
AAGATAGAAACTCAAGAGAGTTGTTTATGAGTATTGTTGAAATGAAAGAATACGATGTTTATAAATTCAATTTGTTAACT
GAGACATTGCAACCTAAGTCAAGAAAGCCAAAGCATGATTTTACAGCTGAAATTATTAGTATTGAAGAAGATGGTGTTGA
GGATGTTTATGATACAACACAAGAAGACTATCACTCTCTGATTTTCAATGGAATTGTTACTGGTAACTGTTCAGAGGTAC
TTCAATCGTCACAAGTATCAGTTTATACGGATTACGATAAAGAGGATGAAATTGGCTTAGATATCTCATGTAATCTTGGC
TCAATGAACATTGTAAATGTAATGAGTAATCAATCAATTGCTTCAACAGTCAGAATAGCAATTGACTCACTGACAACTGT
CACAAGGAAAACAAACATTGTAAATGCTCCAGCAGTTGCGAGAGCAAATACATTAATGAGATCAATTGGTCTAGGGCAGA
TGAACCTCCATGGATTTCTAGCTCAAAATAATATTGCTTATGAAAGTGAAGAAGCTAAGGATTTTGCAAATACATACTTT
ATGATGGTTAACTTCTACTCACTGCAGCGTTCTATGGAAATTGCACGAGAAACAGGGGAGACATACTACAAGTTTGATGG
TTCGACTTATAAATCAGGCGAGTATTTCGAAAAGTACGTAACAAATGATTATAGCCCTCAGTATGAAAAGGTTAAAAAGC
TATTTGGAGATCAACATATTCCTAATATTCAAGATTGGATGAAGCTTAAAGAAGATGTAATGAAATATGGTCTTTATCAT
TCCTATAGACAAGCTATTGCGCCTACGGGAAGCATCTCATATGTTCAATCATCTACAGCAGGTGTAATGCCAATTATGGA
GAGAATTGAGGAACGTACATACGGAAACAGTAAGACATATTATCCGATGCCAGGTTTATCGGCTCAGAATTGGTTCTTCT
ATAAGGAAGCATACGACATGGATATGTTTAAGGTAGTTGATCTTATTGCAACAATTCAGCAGCACGTCGACCAAGGGATT
TCATTTACGTTGTTCTTAAAGGATACGATGACGACGAGAGACCTAAATAGAATAGACCTCTACGCACATCATCGTGGAAT
TAAAACTTTATATTATGCCAGAACTAAAGATACGACCCAAGAGGGATGCTTGTCCTGTGTAGTTTAA

Protein sequence :
MTNTIPNWIKLNNEIMIQKDGKYQFEKDKEAVHSYFVDYINQNTVFFHDLKEKLDYLIKNDYYEEEFLSKYTFEQIKSIY
KIAYSYKFRFPSFMSAFKFYNDYALKTNDKTKILERYEDRVSIVALYCADGDYEKAVEEVHTMMKQEYQPATPTFLNAGR
KRRGEMVSCFLLEVGDSLNDISRAIDISMQLSKLGGGVALNLNKLRAKGEAIKDVENATKGVVGVMKLLDNAFRYADQMG
QRQGSGAVYLSVFHPDITDFLDTKKISADEDVRVKTLSIGVVVPDKFIELAREDKDYYMFYPHSVYKEYGQYLDELDINE
MYDELVENPRVRKAKGNARKLLEQLAILRSESGYPYIMFADNVNKVHPNEHISKVKFSNLCVTGETLLLTENGYEKAADL
YKKQNDLKVVIDNRTKDFAVGSKGTTIVDAIPMQLTKKDAEIFKVKTKQGYEIRATEWHKFYVKRDGEIQKLQLNQLKTG
DKLLVQSAEGAYGKIHEPDLAYIMGIIAGDGTITEKTAKIYLYDNKKVLEQKVTDAVHRIIQKHKVDRAYKHNTSLLPTF
NMANPEKQDLLYMNSTVLFDILKKFGMNKETKTRVPEFIFQANKETQAAYLSGLFQTDGCVNANHKAKALTIELTSIHYE
SLQDVQKLLLNMGVYTTIYSNNKRSQELLPDGKGGSKLYNVKPTHKISIQDRNSRELFMSIVEMKEYDVYKFNLLTETLQ
PKSRKPKHDFTAEIISIEEDGVEDVYDTTQEDYHSLIFNGIVTGNCSEVLQSSQVSVYTDYDKEDEIGLDISCNLGSMNI
VNVMSNQSIASTVRIAIDSLTTVTRKTNIVNAPAVARANTLMRSIGLGQMNLHGFLAQNNIAYESEEAKDFANTYFMMVN
FYSLQRSMEIARETGETYYKFDGSTYKSGEYFEKYVTNDYSPQYEKVKKLFGDQHIPNIQDWMKLKEDVMKYGLYHSYRQ
AIAPTGSISYVQSSTAGVMPIMERIEERTYGNSKTYYPMPGLSAQNWFFYKEAYDMDMFKVVDLIATIQQHVDQGISFTL
FLKDTMTTRDLNRIDLYAHHRGIKTLYYARTKDTTQEGCLSCVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SERP1513 YP_189078.1 truncated ribonucleoside-diphosphate reductase 2, alpha subunit Not tested ¥ÕSP¥â Protein 0.0 50