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Name : nrdF (BSU20040) Accession : NP_389886.2 Strain : Bacillus subtilis 168 Genome accession: NC_000964 Putative virulence/resistance : Unknown Product : ribonucleoside-diphosphate reductase subunit beta Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0208 EC number : 1.17.4.1 Position : 2159981 - 2161778 bp Length : 1798 bp Strand : - Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE DNA sequence : TTGACAAAAATTTATGACGCAGCAAACTGGTCAAAGCATGAAGACGATTTTACCCAAATGTTCTATAACCAAAACGTGAA ACAGTTCTGGCTTCCGGAAGAGATTGCTTTAAACGGCGATCTCCTCACATGGAAGTACCTCGGAAAAAATGAGCAGGACA CTTATATGAAGGTACTGGCCGGACTTACGCTTCTTGATACAGAGCAGGGGAATACGGGGATGCCGATCGTGGCTGAACAC GTAGATGGACATCAAAGAAAGGCAGTTTTAAATTTCATGGCCATGATGGAAAATGCTGTTCATGCAAAGTCTTACAGCAA CATCTTTCTAACATTGGCTCCAACCGAGCAGATCAATGAAGTCTTTGAATGGGTGAAAAACAATAGGTTTCTTCAAAAGA AAGCTAGAACAATTGTTTCAGTCTATAAAACAATCAAGAAAAACGATGAAATTTCTTTATTTAAAGGAATGGTTGCATCT GTGTTCCTGGAGAGTTTTCTTTTCTACTCAGGGTTTTATTACCCACTTTATTTTTATGGACAAGGAAAGTTAATGCAAAG TGGAGAGATCATTAACCTGATTATTTAATAGTCCCTTTTGTCGGCAACGGCAAATGTGAACCTCTCTAATTGCTGGAAAA TCCTTATTAGGACAATCAGCAGCGAAGCTATGCGAACCCAAAGGAGGTGAAAATGATAAGGAAAGAAGTCGAAGAAGCAC CTTGGTGGATAACGGAAACGGGAGTTATCATATCAAAAAAATTAAAGAAACCAAGAAAGACATTTATTACTCCACATGGC TATGAAATGATAGGATACACGCATCCGAAAAAAGGAACACAGAACTATTTAGTACATAGGTTAGTCGCAAAATATTTTAT TTATGATATACCAAAAGGAATGTTTGTAAACCACATAGATGGAAATAAACTAAACAACCACGTTCGGAACTTAGAAATAG TTACACCTAAAGAAAATACTCTACATGCAATGAAAATTGGATTAATGTCAGGACAACCTGGAGAAAGTAATTCAATGTCA AAGCTCACTAATATGGAGGCAACAAATTTAATCTATGATTTGATTGCTGGAATGAACAATGTTGAAGCTGGTGAAAAATA CAGCCTTCATCCTCGTTACGTTAGTCTAATTCGACATAAAAGAAGATGGAAGACTTTATGGGATCGCATAGAACGTTCAA CGACTATCGCATAGGCGGCGAAATTCCGCAAAACGAGTAGGGCGCAAGCTATTGGCGTGGGTGAGAACCCCTTAAATCGA AACGGGAGGCATCCTACAGGGATGATGATATAGTCTGCTCCTTACGGTAACGTAAGGCGGTTGCGACAGAGCAACGAACC GAAAGTAGCGAACTCGGTTGAACTAAGGGTATTAGAGACGAAGCGATACATGGCGTATATGTAGGATTGTTAGCTCAAGA GATTTATAAGAAGCAAACGCCACAGAAGCAAAAAGAACTGTACGCATGGGCTTTAAACTTACTGCAGGAACTTTACGAAA ATGAATTGGAGTATACAGAAGATGTCTATGATCAGGTTGGATTAGCTCCAGATGTAAAGAAATTCATCAGATACAACGCA AATAAAGCTTTAAACAATCTGGGCTTTGATCATTGGTTTGAAGAAGAGGATGTTAATCCAATTGTTATCAATGGTTTGAA CACTAAGACTAAATCCCATGACTTCTTTTCAACTAAAGGGAATGGATACAAAAAAGCAACAGTGGAGCCTTTAAAGGATT CAGATTTCATTTTTACCGAGAAAGGATGTATTCAATGA Protein sequence : MTKIYDAANWSKHEDDFTQMFYNQNVKQFWLPEEIALNGDLLTWKYLGKNEQDTYMKVLAGLTLLDTEQGNTGMPIVAEH VDGHQRKAVLNFMAMMENAVHAKSYSNIFLTLAPTEQINEVFEWVKNNRFLQKKARTIVSVYKTIKKNDEISLFKGMVAS VFLESFLFYSGFYYPLYFYGQGKLMQSGEIINLIIRDEAIHGVYVGLLAQEIYKKQTPQKQKELYAWALNLLQELYENEL EYTEDVYDQVGLAPDVKKFIRYNANKALNNLGFDHWFEEEDVNPIVINGLNTKTKSHDFFSTKGNGYKKATVEPLKDSDF IFTEKGCIQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| nrdF | YP_189075.1 | ribonucleotide-diphosphate reductase subunit beta | Not tested | ¥ÕSP¥â | Protein | 2e-53 | 47 |
| cur_1479 | YP_001800873.1 | ribonucleoside-diphosphate reductase subunit beta | Not tested | Not named | Protein | 3e-48 | 42 |
