Gene Information

Name : dhaS (BSU19310)
Accession : NP_389813.1
Strain : Bacillus subtilis 168
Genome accession: NC_000964
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase DhaS
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.-
Position : 2100580 - 2102067 bp
Length : 1488 bp
Strand : +
Note : Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme

DNA sequence :
ATGAGTTCTTTAACGATGCAAGTGACGAAAAGGCTGGAGACATTTTTACAGGGAACAAAGAAGCTTTATATTGACGGAAA
GTTTGTTCCGAGTGCCTCAGGGGCAACCTTTGACACTCCAAACCCGGCGACCGGCGAAACCTTGATGACGCTGTATGAAG
CCCAGGCTGCGGATGTGGACAAAGCTGTTAAAGCTGCCCGGAAAGCCTTTGACCAAGGTGAATGGAGAACAATGTCTCCA
GCTTCGAGAAGCAGACTGATGTATAAGCTGGCAGACTTAATGGAAGAGCATAAAACTGAGCTTGCTCAGCTTGAAACACT
TGATAATGGGAAACCGATCAATGAAACGACTAATGGAGATATTCCGCTGGCTATTGAGCATATGCGCTATTACGCCGGCT
GGTGTACAAAAATAACAGGACAGACGATTCCGGTTTCCGGCGCTTATTTTAATTATACGCGTCATGAGCCTGTCGGTGTC
GTCGGCCAGATCATTCCATGGAATTTCCCGCTCCTGATGGCGATGTGGAAAATGGGCGCGGCACTTGCAACAGGCTGTAC
AATCGTCCTCAAACCGGCTGAACAAACACCGCTTTCAGCTCTTTATTTGGCAGAATTAATTGACCAAGCCGGTTTCCCTG
CCGGTGTAATCAACATCATCCCAGGATTCGGTGAAGATGCGGGAGAAGCGCTGACGAACCACGAAGCGGTTGATAAAATT
GCCTTTACCGGTTCCACTGAAATCGGAAAGAAAATCATGTCCACCGCAGCGAAAAGCATTAAGCGTGTGACATTGGAGCT
GGGCGGAAAATCGCCTAATATTCTTCTGCCGGATGCGAATTTAAAAAAAGCCATCCCGGGCGCTTTAAACGGTGTGATGT
TTAACCAGGGCCAAGTCTGCTGTGCGGGCTCACGTGTCTTCATTCATAAAGACCAATATGATGAAGTTGTTGATGAAATG
GCATCCTATGCTGAGTCACTCCGCCAAGGAGCGGGACTTCATAAAGATACTCAAATCGGGCCTCTCGTAAGCAAGGAACA
GCATGAGCGCGTTCTTTCCTATATTCAAAAAGGAAAAGATGAAGGAGCAAAAGCAGTGACCGGCGGAAGCTGTCCTTTTG
AAGCAGGATATTTTGTCGCACCGACTGTGTTTGCGAATGTTGAAGACGAAATGACCATCGCAAAAGAAGAAATTTTCGGA
CCCGTGCTGACTGCAATTCCGTACGAAACAGTCGATGAAGTTATTGAACGGGCAAACCATTCAGAATATGGGCTTGCAGC
CGGACTATGGACAGAGAACGTCAAGCAGGCTCACTATATCGCGGACCGACTTCAAGCCGGAACCGTTTGGGTCAACTGCT
ATAATGTGTTTGACGCGGCGTCTCCATTTGGCGGTTATAAACAGTCAGGACTCGGACGAGAAATGGGATCATATGCCTTG
GATAATTACACAGAAGTCAAAAGTGTATGGGTAAACCTTGAAGACTAA

Protein sequence :
MSSLTMQVTKRLETFLQGTKKLYIDGKFVPSASGATFDTPNPATGETLMTLYEAQAADVDKAVKAARKAFDQGEWRTMSP
ASRSRLMYKLADLMEEHKTELAQLETLDNGKPINETTNGDIPLAIEHMRYYAGWCTKITGQTIPVSGAYFNYTRHEPVGV
VGQIIPWNFPLLMAMWKMGAALATGCTIVLKPAEQTPLSALYLAELIDQAGFPAGVINIIPGFGEDAGEALTNHEAVDKI
AFTGSTEIGKKIMSTAAKSIKRVTLELGGKSPNILLPDANLKKAIPGALNGVMFNQGQVCCAGSRVFIHKDQYDEVVDEM
ASYAESLRQGAGLHKDTQIGPLVSKEQHERVLSYIQKGKDEGAKAVTGGSCPFEAGYFVAPTVFANVEDEMTIAKEEIFG
PVLTAIPYETVDEVIERANHSEYGLAAGLWTENVKQAHYIADRLQAGTVWVNCYNVFDAASPFGGYKQSGLGREMGSYAL
DNYTEVKSVWVNLED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 4e-92 47
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-90 47
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-90 47
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-90 45
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-90 45
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-90 45
hpaE AAO17179.1 HpaE Not tested tcd island Protein 7e-75 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhaS NP_389813.1 aldehyde dehydrogenase DhaS VFG0082 Protein 8e-91 47