Gene Information

Name : penP (BSU18800)
Accession : NP_389761.1
Strain : Bacillus subtilis 168
Genome accession: NC_000964
Putative virulence/resistance : Resistance
Product : beta-lactamase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2367
EC number : 3.5.2.6
Position : 2048533 - 2049453 bp
Length : 921 bp
Strand : +
Note : Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16944130, 7789815; Product type e: enzyme

DNA sequence :
ATGAAGTTGAAAACTAAAGCGTCAATAAAATTCGGAATATGTGTTGGGCTTTTATGTTTAAGCATTACTGGTTTCACACC
TTTTTTCAACTCAACACATGCCGAAGCAAAATCCATAGAAGACACAAACATGGCAAGCTGTATAACGAATAAAAAATTTG
TTCAACTTGAGAAAAAATTTGATGCCAGGCTTGGTGTTTATGCAATTGATATAGGTTCAAACAAGACAATCGCCTATCGG
CCGAATGAACGATTTGCTTACGCATCAACCTATAAAGTTCTAGCCGCAGCTGCTGTCCTGAAGAAAAACTCAATTGAAAA
ACTTAATGAAGTCATCCACTACAGCAAGGACGATCTTGTTACATATTCTCCAATCACAGAGAAACACCTAGATACAGGCA
TGAGCCTAAAAGAAATCTCGGAAGCGGCTATCCGTTACAGCGATAATACCGCTGGGAACATCTTGTTGCAACAGCTTGGC
GGCCCTAAAGGTTTTGAAAAGTCACTGAAACAGATTGGGGATCATGTAACGAAAGCTAAACGATTCGAGACGGATCTAAA
CTCTGCGATTCCTGGTGATATTCGTGACACCAGCACCGCAAAAGCACTGGCAACCGATCTTAAAGCCTTCACTTTAGATA
ACACTCTCACGACTGACAAACGCATGATCTTAACCGATTGGATGCGAGGCAATGCTACTGGTGACGAACTGATTCGGGCA
GGCGCTCCAATAGGATGGGAAGTCGGCGATAAATCCGGAGCCGGAAGTTACGGGACACGAAACGACATTGCTATCGTTTG
GCCGCCAAACAGAGCTCCTATTGTTGTGGCAATTCTGTCAAACCGCTTTACGAAAGATGCTAATTATGATAATGCTCTTA
TCGCTGAGGCTGCAAAAGTCGTCCTTAACGATCTCAAATAA

Protein sequence :
MKLKTKASIKFGICVGLLCLSITGFTPFFNSTHAEAKSIEDTNMASCITNKKFVQLEKKFDARLGVYAIDIGSNKTIAYR
PNERFAYASTYKVLAAAAVLKKNSIEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLG
GPKGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRMILTDWMRGNATGDELIRA
GAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNRFTKDANYDNALIAEAAKVVLNDLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
blaCTX-M2 ACF06162.1 beta-lactamase CTX-M2 Not tested Tn5036-like Protein 6e-44 44
blaTEM-1b ACK44542.1 BlaTEM-1b beta lactamase Not tested SGI1 Protein 9e-37 44
blaTEM-1b ACF06168.1 beta-lactamase TEM-1b Not tested Tn5036-like Protein 9e-37 44
blaTEM-1 ADI24150.1 beta-lactamase TEM-1 Not tested AbaR1 Protein 9e-37 44
blaTEM-1b AGK07035.1 TEM-1b beta lactamase Not tested SGI1 Protein 9e-37 44
blaTEM-1b AGK07093.1 TEM-1b beta lactamase Not tested SGI1 Protein 9e-37 44
blaTEM AFV53104.1 TEM-1 beta-lactamase Not tested AbGRI2-1 Protein 9e-37 44
ABTW07_3874 YP_005797122.1 beta-lactamase TEM Not tested AbaR4e Protein 1e-36 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
penP NP_389761.1 beta-lactamase AF367983.gene.p01 Protein 5e-93 67
penP NP_389761.1 beta-lactamase DQ663489.gene.p01 Protein 2e-44 49
penP NP_389761.1 beta-lactamase DQ328639.gene.p01 Protein 2e-44 49
penP NP_389761.1 beta-lactamase AY005110.1.gene1.p1 Protein 7e-43 48
penP NP_389761.1 beta-lactamase AY303807.gene.p01 Protein 3e-43 47
penP NP_389761.1 beta-lactamase AY267213.1.gene1.p01 Protein 2e-45 47
penP NP_389761.1 beta-lactamase AB177384.1.gene1.p01 Protein 3e-45 47
penP NP_389761.1 beta-lactamase EF210159.1.gene1.p01 Protein 2e-45 47
penP NP_389761.1 beta-lactamase EF581888.1.gene1.p01 Protein 3e-47 46
penP NP_389761.1 beta-lactamase JF274247.1.gene1.p01 Protein 6e-47 46
penP NP_389761.1 beta-lactamase AF325133.1.gene1.p1 Protein 5e-47 46
penP NP_389761.1 beta-lactamase AY143430.1.gene1.p01 Protein 9e-47 46
penP NP_389761.1 beta-lactamase FJ214367.1.gene1.p1 Protein 4e-47 46
penP NP_389761.1 beta-lactamase FJ214366.1.gene1.p1 Protein 5e-47 46
penP NP_389761.1 beta-lactamase HQ833652.1.gene1.p01 Protein 4e-47 46
penP NP_389761.1 beta-lactamase HM803271.1.gene1.p01 Protein 6e-47 46
penP NP_389761.1 beta-lactamase HQ398215.1.gene1.p01 Protein 5e-47 46
penP NP_389761.1 beta-lactamase AY156923.1.gene1.p01 Protein 3e-47 46
penP NP_389761.1 beta-lactamase AF252623.2.gene1.p01 Protein 6e-47 46
penP NP_389761.1 beta-lactamase AY847145.1.gene1.p01 Protein 2e-46 46
penP NP_389761.1 beta-lactamase AF252622.2.gene2.p01 Protein 5e-47 46
penP NP_389761.1 beta-lactamase AY033516.1.gene2.p01 Protein 6e-47 46
penP NP_389761.1 beta-lactamase AY847146.1.gene1.p01 Protein 7e-47 46
penP NP_389761.1 beta-lactamase AY847143.1.gene1.p01 Protein 1e-46 46
penP NP_389761.1 beta-lactamase AF325134.1.gene1.p1 Protein 4e-47 46
penP NP_389761.1 beta-lactamase AY822595.1.gene1.p01 Protein 6e-47 46
penP NP_389761.1 beta-lactamase AF395881.gene.p01 Protein 4e-50 46
penP NP_389761.1 beta-lactamase EU729727.1.gene1.p1 Protein 2e-50 46
penP NP_389761.1 beta-lactamase GQ140348.1.gene1.p01 Protein 6e-50 46
penP NP_389761.1 beta-lactamase FJ234412.1.gene1.p01 Protein 2e-50 46
penP NP_389761.1 beta-lactamase EF219142.1.gene1.p01 Protein 4e-45 46
penP NP_389761.1 beta-lactamase FJ873739.1.gene1.p01 Protein 2e-45 46
penP NP_389761.1 beta-lactamase AJ704396.1.gene1.p01 Protein 3e-45 46
penP NP_389761.1 beta-lactamase EF426798.1.gene1.p1 Protein 4e-45 46
penP NP_389761.1 beta-lactamase EU402393.1.gene1.p1 Protein 2e-45 46
penP NP_389761.1 beta-lactamase DQ061159.1.gene1.p01 Protein 2e-45 46
penP NP_389761.1 beta-lactamase AY080894.1.gene1.p01 Protein 4e-45 46
penP NP_389761.1 beta-lactamase AY995206.gene.p01 Protein 3e-45 46
penP NP_389761.1 beta-lactamase AY598759.gene.p01 Protein 8e-45 46
penP NP_389761.1 beta-lactamase AY238472.1.gene1.p01 Protein 2e-45 46
penP NP_389761.1 beta-lactamase AJ549244.1.gene1.p01 Protein 3e-45 46
penP NP_389761.1 beta-lactamase EU202673.2.gene1.p2 Protein 5e-45 46
penP NP_389761.1 beta-lactamase AY649755.1.gene1.p01 Protein 4e-45 46
penP NP_389761.1 beta-lactamase AB284167.2.gene1.p01 Protein 1e-46 46
penP NP_389761.1 beta-lactamase Y10278.1.gene1.p01 Protein 4e-45 46
penP NP_389761.1 beta-lactamase EU177100.1.gene1.p01 Protein 4e-45 46
penP NP_389761.1 beta-lactamase AJ557142.gene.p01 Protein 3e-45 46
penP NP_389761.1 beta-lactamase X92506.gene.p01 Protein 3e-45 46
penP NP_389761.1 beta-lactamase AF255298.1.gene1.p1 Protein 8e-45 46
penP NP_389761.1 beta-lactamase DQ268764.2.gene6.p01 Protein 2e-45 46
penP NP_389761.1 beta-lactamase AF305837.gene.p01 Protein 4e-45 46
penP NP_389761.1 beta-lactamase AF488377.1.gene1.p1 Protein 2e-45 46
penP NP_389761.1 beta-lactamase AY292654.1.gene1.p1 Protein 3e-45 46
penP NP_389761.1 beta-lactamase JF966749.1.gene1.p01 Protein 5e-45 46
penP NP_389761.1 beta-lactamase GQ149243.1.gene1.p01 Protein 2e-44 45
penP NP_389761.1 beta-lactamase EF418608.1.gene1.p01 Protein 1e-46 45
penP NP_389761.1 beta-lactamase JF274246.1.gene1.p01 Protein 6e-47 45
penP NP_389761.1 beta-lactamase EU545409.1.gene1.p1 Protein 1e-46 45
penP NP_389761.1 beta-lactamase FJ214368.1.gene1.p1 Protein 4e-46 45
penP NP_389761.1 beta-lactamase AJ416345.gene.p01 Protein 1e-46 45
penP NP_389761.1 beta-lactamase JF274243.1.gene1.p01 Protein 2e-46 45
penP NP_389761.1 beta-lactamase HQ833651.1.gene1.p01 Protein 6e-47 45
penP NP_389761.1 beta-lactamase DQ211987.1.gene1.p01 Protein 2e-46 45
penP NP_389761.1 beta-lactamase EU136031.3.gene1.p3 Protein 4e-47 45
penP NP_389761.1 beta-lactamase AY029068.1.gene1.p1 Protein 8e-47 45
penP NP_389761.1 beta-lactamase AF174129.3.gene9.p01 Protein 1e-46 45
penP NP_389761.1 beta-lactamase HM755448.1.gene1.p01 Protein 4e-47 45
penP NP_389761.1 beta-lactamase HQ166709.1.gene1.p01 Protein 2e-46 45
penP NP_389761.1 beta-lactamase FJ907381.1.gene1.p01 Protein 5e-47 45
penP NP_389761.1 beta-lactamase FJ214369.1.gene1.p1 Protein 2e-46 45
penP NP_389761.1 beta-lactamase EU555534.1.gene1.p01 Protein 2e-49 45
penP NP_389761.1 beta-lactamase HM066995.1.gene1.p01 Protein 8e-49 45
penP NP_389761.1 beta-lactamase AY034847.1.gene1.p01 Protein 4e-49 45
penP NP_389761.1 beta-lactamase AF297554.1.gene1.p1 Protein 9e-49 45
penP NP_389761.1 beta-lactamase HQ641421.1.gene1.p01 Protein 7e-49 45
penP NP_389761.1 beta-lactamase HQ913565.1.gene1.p01 Protein 1e-46 45
penP NP_389761.1 beta-lactamase JN227085.1.gene1.p01 Protein 2e-44 45
penP NP_389761.1 beta-lactamase DQ223685.1.gene1.p01 Protein 4e-45 45
penP NP_389761.1 beta-lactamase HQ398214.1.gene1.p01 Protein 9e-45 45
penP NP_389761.1 beta-lactamase DQ810789.1.gene1.p01 Protein 4e-45 45
penP NP_389761.1 beta-lactamase AY515297.1.gene1.p1 Protein 8e-44 45
penP NP_389761.1 beta-lactamase DQ256091.1.gene1.p1 Protein 4e-45 45
penP NP_389761.1 beta-lactamase FJ815436.1.gene1.p01 Protein 3e-44 45
penP NP_389761.1 beta-lactamase AY847148.1.gene1.p01 Protein 5e-44 45
penP NP_389761.1 beta-lactamase GQ351346.1.gene1.p01 Protein 3e-45 45
penP NP_389761.1 beta-lactamase AM411407.1.gene1.p01 Protein 5e-45 45
penP NP_389761.1 beta-lactamase DQ885477.1.gene1.p01 Protein 4e-45 45
penP NP_389761.1 beta-lactamase JF274242.1.gene1.p01 Protein 4e-46 45
penP NP_389761.1 beta-lactamase DQ023162.1.gene1.p1 Protein 7e-42 45
penP NP_389761.1 beta-lactamase HM167760.1.gene1.p01 Protein 6e-43 45
penP NP_389761.1 beta-lactamase FJ971899.1.gene1.p1 Protein 5e-42 45
penP NP_389761.1 beta-lactamase AF518567.2.gene4.p01 Protein 4e-42 45
penP NP_389761.1 beta-lactamase GQ870432.1.gene1.p1 Protein 5e-42 45
penP NP_389761.1 beta-lactamase AY954516.1.gene1.p1 Protein 5e-42 45
penP NP_389761.1 beta-lactamase AM982522.2.gene1.p01 Protein 2e-42 45
penP NP_389761.1 beta-lactamase AY157676.1.gene1.p01 Protein 1e-42 45
penP NP_389761.1 beta-lactamase AM941159.1.gene1.p01 Protein 4e-37 45
penP NP_389761.1 beta-lactamase X54606.1.gene1.p01 Protein 2e-37 45
penP NP_389761.1 beta-lactamase EF136377.1.gene1.p01 Protein 2e-37 45
penP NP_389761.1 beta-lactamase AJ416344.1.gene1.p01 Protein 1e-43 44
penP NP_389761.1 beta-lactamase DQ408762.1.gene1.p1 Protein 3e-44 44
penP NP_389761.1 beta-lactamase DQ102702.1.gene1.p1 Protein 6e-44 44
penP NP_389761.1 beta-lactamase EF374097.1.gene1.p01 Protein 3e-44 44
penP NP_389761.1 beta-lactamase AJ567481.1.gene1.p01 Protein 5e-44 44
penP NP_389761.1 beta-lactamase DQ125241.gene.p01 Protein 4e-44 44
penP NP_389761.1 beta-lactamase GU127598.1.gene1.p1 Protein 3e-44 44
penP NP_389761.1 beta-lactamase U95364.1.gene1.p01 Protein 2e-44 44
penP NP_389761.1 beta-lactamase Y14156.1.gene1.p01 Protein 5e-43 44
penP NP_389761.1 beta-lactamase GQ149244.1.gene1.p01 Protein 3e-44 44
penP NP_389761.1 beta-lactamase HM776707.1.gene1.p1 Protein 4e-44 44
penP NP_389761.1 beta-lactamase X92507.1.gene1.p01 Protein 4e-44 44
penP NP_389761.1 beta-lactamase JF949915.1.gene1.p01 Protein 4e-37 44
penP NP_389761.1 beta-lactamase JF949916.1.gene1.p01 Protein 5e-37 44
penP NP_389761.1 beta-lactamase AY130282.1.gene1.p1 Protein 6e-37 44
penP NP_389761.1 beta-lactamase AY039040.1.gene1.p01 Protein 5e-37 44
penP NP_389761.1 beta-lactamase AY327539.1.gene1.p01 Protein 1e-36 44
penP NP_389761.1 beta-lactamase AF427127.1.gene1.p01 Protein 1e-36 44
penP NP_389761.1 beta-lactamase Y14574.2.gene1.p01 Protein 5e-37 44
penP NP_389761.1 beta-lactamase AF397068.1.gene1.p1 Protein 6e-37 44
penP NP_389761.1 beta-lactamase DQ679961.1.gene1.p01 Protein 1e-36 44
penP NP_389761.1 beta-lactamase HQ451074.1.gene4.p01 Protein 5e-37 44
penP NP_389761.1 beta-lactamase Y17583.1.gene1.p01 Protein 7e-37 44
penP NP_389761.1 beta-lactamase AY092401.1.gene1.p1 Protein 9e-37 44
penP NP_389761.1 beta-lactamase X64523.1.gene1.p01 Protein 5e-37 44
penP NP_389761.1 beta-lactamase AF516719.1.gene1.p1 Protein 6e-37 44
penP NP_389761.1 beta-lactamase GU550123.1.gene1.p1 Protein 1e-36 44
penP NP_389761.1 beta-lactamase DQ286729.1.gene1.p1 Protein 3e-37 44
penP NP_389761.1 beta-lactamase NC_010558.1.6276043. Protein 5e-37 44
penP NP_389761.1 beta-lactamase AF427129.1.gene1.p01 Protein 7e-37 44
penP NP_389761.1 beta-lactamase AY368237.1.gene1.p1 Protein 6e-37 44
penP NP_389761.1 beta-lactamase EU274580.1.gene1.p1 Protein 1e-36 44
penP NP_389761.1 beta-lactamase DQ072853.1.gene1.p01 Protein 5e-37 44
penP NP_389761.1 beta-lactamase AY874537.1.gene1.p01 Protein 6e-37 44
penP NP_389761.1 beta-lactamase AF397067.1.gene1.p1 Protein 4e-37 44
penP NP_389761.1 beta-lactamase AY307100.1.gene1.p1 Protein 6e-37 44
penP NP_389761.1 beta-lactamase AF190694.1.gene1.p01 Protein 8e-37 44
penP NP_389761.1 beta-lactamase AY956335.1.gene1.p1 Protein 5e-37 44
penP NP_389761.1 beta-lactamase AF495873.1.gene1.p1 Protein 6e-37 44
penP NP_389761.1 beta-lactamase JN416112.1.gene1.p01 Protein 1e-36 44
penP NP_389761.1 beta-lactamase EU815939.1.gene1.p1 Protein 5e-37 44
penP NP_389761.1 beta-lactamase AF190693.1.gene1.p01 Protein 7e-37 44
penP NP_389761.1 beta-lactamase AF347054.1.gene1.p1 Protein 9e-37 44
penP NP_389761.1 beta-lactamase AY589493.1.gene1.p01 Protein 6e-37 44
penP NP_389761.1 beta-lactamase AJ866988.1.gene1.p01 Protein 1e-36 44
penP NP_389761.1 beta-lactamase FJ405211.1.gene1.p01 Protein 3e-37 44
penP NP_389761.1 beta-lactamase FQ312006.1.gene118.p Protein 5e-37 44
penP NP_389761.1 beta-lactamase AY072920.1.gene1.p1 Protein 7e-37 44
penP NP_389761.1 beta-lactamase JN227084.1.gene1.p01 Protein 8e-37 44
penP NP_389761.1 beta-lactamase AF351241.1.gene1.p01 Protein 5e-37 44
penP NP_389761.1 beta-lactamase Y17582.1.gene1.p01 Protein 2e-37 44
penP NP_389761.1 beta-lactamase NC_011586.7045197.p0 Protein 5e-37 44
penP NP_389761.1 beta-lactamase AF506748.1.gene1.p1 Protein 6e-37 44
penP NP_389761.1 beta-lactamase AF427128.1.gene1.p01 Protein 4e-37 44
penP NP_389761.1 beta-lactamase AF427130.1.gene1.p01 Protein 6e-37 44
penP NP_389761.1 beta-lactamase JN254627.1.gene1.p01 Protein 8e-37 44
penP NP_389761.1 beta-lactamase AJ746225.1.gene1.p01 Protein 1e-36 44
penP NP_389761.1 beta-lactamase HQ529916.1.gene1.p01 Protein 2e-37 44
penP NP_389761.1 beta-lactamase AM183304.1.gene1.p01 Protein 5e-37 44
penP NP_389761.1 beta-lactamase X65254.1.gene1.p01 Protein 6e-37 44
penP NP_389761.1 beta-lactamase AF516720.1.gene1.p1 Protein 4e-37 44
penP NP_389761.1 beta-lactamase FJ919776.1.gene1.p01 Protein 5e-37 44
penP NP_389761.1 beta-lactamase GU371926.1.gene94.p0 Protein 7e-37 44
penP NP_389761.1 beta-lactamase AY847144.1.gene1.p01 Protein 5e-47 43
penP NP_389761.1 beta-lactamase AY847147.1.gene1.p01 Protein 8e-47 43
penP NP_389761.1 beta-lactamase AF189721.1.gene1.p01 Protein 1e-43 43
penP NP_389761.1 beta-lactamase Z28968.gene.p01 Protein 2e-46 43
penP NP_389761.1 beta-lactamase AF275256.gene.p01 Protein 5e-48 43
penP NP_389761.1 beta-lactamase AJ005045.gene.p01 Protein 2e-42 43
penP NP_389761.1 beta-lactamase AY750914.gene.p01 Protein 5e-43 42
penP NP_389761.1 beta-lactamase AB205197.1.gene1.p01 Protein 4e-43 42
penP NP_389761.1 beta-lactamase AY037780.1.gene1.p01 Protein 1e-36 42
penP NP_389761.1 beta-lactamase U50278.1.gene2.p01 Protein 8e-48 41
penP NP_389761.1 beta-lactamase AY178993.1.gene1.p01 Protein 1e-43 41
penP NP_389761.1 beta-lactamase HQ637576.1.gene1.p01 Protein 8e-37 41