Gene Information

Name : nrdE (BSU17380)
Accession : NP_389620.1
Strain : Bacillus subtilis 168
Genome accession: NC_000964
Putative virulence/resistance : Unknown
Product : ribonucleoside-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 1868969 - 1871071 bp
Length : 2103 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
TTGTCACAAAATCAAGTGCCAAAATGGATCCAGTTAAATAACGAAATCATGATCCAAAAAGATGGGAAATTCCAGTTTGA
TAAGGATAAAGAAGCTGTACATAGCTATTTTGTAGATTATATCAATCAAAACACAGTCTTCTTTCACAATTTAAAAGAGA
AGCTGGATTATTTGGTTGAAAACCAATACTACGAAGAGGAATTCTTAAGCCTTTATTCTTTTGAAGACATTAAAGAAGTG
TTTAAGACAGCTTACGCTAAGAAGTTTCGTTTTCCTTCCTTCATGAGTGCGTTTAAATTCTATAATGACTATGCTTTGAA
AACGAATGACAAGAAAAAAATCCTCGAGCGTTATGAGGACCGGATCTCAATTGTTGCGCTGTTCTTCGCTAACGGCGACA
CTGAGAAAGCAAAAGAATATGTAAACCTGATGATCAATCAAGAATATCAGCCGAGCACACCGACATTTTTGAATGCCGGC
AGAAAACGCCGCGGTGAACTTGTGAGCTGCTTCTTGCTCGAAGTTAATGATTCTTTAAATGACATTTCAAGAGCAATCGA
TATCTCCATGCAGCTTTCTAAGCTTGGTGGCGGGGTTTCTCTTAACCTGTCCAAGCTTCGCGCGAAAGGTGAAGCCATTA
AAGATGTTGAGAATGCGACAAAAGGCGTTGTAGGCGTCATGAAGCTTCTTGATAACGCGTTCCGTTACGCTGACCAAATG
GGACAAAGACAAGGCTCCGGCGCGGCGTATTTAAACATTTTCCACCGCGATATCAATGATTTTCTTGATACGAAAAAGAT
TTCTGCGGATGAAGATGTGCGTGTCAAAACGCTTTCGATCGGTGTTGTCATTCCGGATAAGTTCGTTGAGCTTGCACGCG
AGGACAAAGCGGCTTATGTATTCTACCCGCACACGATTTATAAAGAGTACGGCCAGCACATGGATGAGATGGACATGAAC
GAAATGTACGACAAGTTTGTCGACAACCCTCGGGTGAAAAAGGAAAAAATCAACCCGCGGAAACTGCTTGAAAAATTGGC
GATGCTTCGTTCTGAATCAGGCTATCCATACATCATGTTCCAAGATAACGTCAATAAAGTGCATGCGAATAACCATATTT
CCAAGGTCAAATTTTCTAACCTTTGCTCTGAAGTGCTGCAGGCATCTCAAGTTTCTTCATACACAGACTATGATGAAGAA
GATGAAATCGGTCTGGATATTTCCTGCAACCTGGGTTCGCTTAACATTCTCAATGTCATGGAGCATAAATCAATCGAAAA
GACAGTCAAGCTTGCGACAGACTCTTTAACACACGTGTCTGAAACAACAGACATCCGTAATGCGCCTGCTGTAAGACGGG
CAAACAAAGCGATGAAATCAATCGGCCTCGGTGCTATGAACCTTCACGGCTACCTTGCGCAAAACGGCATTGCGTATGAA
AGTCCGGAAGCGCGTGACTTTGCAAACACGTTCTTTATGATGGTGAATTTCTACTCCATCCAGCGTTCTGCGGAAATCGC
AAAAGAGAAGGGCGAAACGTTTGATCAATATGAAGGATCAACCTATGCGACAGGTGAATACTTCGACAAATACGTTTCAA
CTGATTTCTCACCGAAATACGAAAAAATCGCTAATCTGTTTGAAGGTATGCATATCCCGACGACAGAGGACTGGAAAAAG
CTAAAAGCATTTGTCGCTGAACACGGTATGTATCACAGCTACAGATTATGCATTGCGCCGACAGGCTCTATCTCATACGT
TCAATCAAGCACGGCGTCTGTTATGCCGATTATGGAACGGATTGAAGAACGAACATACGGCAACTCAAAAACGTACTACC
CAATGCCTGGGCTTGCATCTAATAACTGGTTCTTCTATAAAGAAGCCTACGATATGGACATGTTCAAGGTTGTGGATATG
ATCGCCACTATCCAGCAGCACATTGATCAGGGAATCAGCTTTACATTGTTCTTAAAAGACACAATGACGACCCGAGATTT
AAACCGAATCGATCTGTATGCACATCATAGAGGAATTAAAACCATTTACTATGCAAGAACGAAAGATACTGGGCAAGACA
GCTGCCTTTCTTGTGTTGTTTGA

Protein sequence :
MSQNQVPKWIQLNNEIMIQKDGKFQFDKDKEAVHSYFVDYINQNTVFFHNLKEKLDYLVENQYYEEEFLSLYSFEDIKEV
FKTAYAKKFRFPSFMSAFKFYNDYALKTNDKKKILERYEDRISIVALFFANGDTEKAKEYVNLMINQEYQPSTPTFLNAG
RKRRGELVSCFLLEVNDSLNDISRAIDISMQLSKLGGGVSLNLSKLRAKGEAIKDVENATKGVVGVMKLLDNAFRYADQM
GQRQGSGAAYLNIFHRDINDFLDTKKISADEDVRVKTLSIGVVIPDKFVELAREDKAAYVFYPHTIYKEYGQHMDEMDMN
EMYDKFVDNPRVKKEKINPRKLLEKLAMLRSESGYPYIMFQDNVNKVHANNHISKVKFSNLCSEVLQASQVSSYTDYDEE
DEIGLDISCNLGSLNILNVMEHKSIEKTVKLATDSLTHVSETTDIRNAPAVRRANKAMKSIGLGAMNLHGYLAQNGIAYE
SPEARDFANTFFMMVNFYSIQRSAEIAKEKGETFDQYEGSTYATGEYFDKYVSTDFSPKYEKIANLFEGMHIPTTEDWKK
LKAFVAEHGMYHSYRLCIAPTGSISYVQSSTASVMPIMERIEERTYGNSKTYYPMPGLASNNWFFYKEAYDMDMFKVVDM
IATIQQHIDQGISFTLFLKDTMTTRDLNRIDLYAHHRGIKTIYYARTKDTGQDSCLSCVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 1e-164 49