Gene Information

Name : serS (BSU00130)
Accession : NP_387894.1
Strain : Bacillus subtilis 168
Genome accession: NC_000964
Putative virulence/resistance : Unknown
Product : serine--tRNA ligase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 20880 - 22157 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTTGATACGAAAATGCTGAGAGCAAATTTTCAAGAAATTAAAGCAAAGCTTGTACACAAAGGCGAAGACTTAACTGA
TTTTGATAAGTTTGAGGCGCTGGATGATAGACGAAGAGAGCTTATCGGCAAGGTTGAAGAGTTAAAAGGAAAACGAAATG
AAGTTTCTCAGCAGGTTGCTGTGCTGAAGCGTGAGAAAAAAGACGCGGATCACATTATTAAAGAAATGCGTGAAGTCGGC
GAGGAAATTAAAAAGCTCGATGAAGAATTACGGACAGTGGAAGCTGAGCTTGATACAATCCTGCTCTCAATCCCGAATAT
TCCGCATGAGTCTGTACCTGTCGGTGAAACAGAAGACGACAACGTAGAAGTGCGTAAATGGGGTGAAAAGCCTTCATTTG
CTTATGAGCCGAAGCCGCACTGGGATATTGCGGATGAGCTGGGTATTCTGGATTTTGAACGTGCTGCCAAAGTAACAGGA
AGCCGTTTCGTGTTCTATAAAGGCTTAGGTGCTCGTCTGGAGCGTGCGCTTTATAACTTTATGCTTGATCTGCATGTGGA
TGAGTATAACTACACTGAAGTGATCCCGCCATATATGGTAAACCGCGCAAGCATGACGGGAACGGGGCAGCTTCCTAAAT
TTGAAGAGGATGCATTTAAAATCAGAGAAGAAGATTATTTCTTAATTCCAACGGCGGAAGTGCCGATTACAAACATGCAT
CGCGATGAAATCCTTTCAGGTGACAGCCTGCCGATCAACTATGCGGCATTCAGTGCTTGCTTCCGTTCTGAAGCTGGTTC
AGCAGGACGTGACACACGCGGATTAATTCGTCAGCACCAATTTAATAAAGTTGAGCTTGTAAAGTTTGTGAAGCCTGAAG
ATTCTTATGAAGAATTAGAGAAACTTACAAACCAAGCAGAACGGGTTCTTCAGCTGCTTGAGCTTCCATACCGTGTCATG
AGCATGTGTACGGGTGACTTAGGCTTTACGGCTGCGAAAAAATACGATATCGAAGTTTGGATTCCAAGCCAAGACACATA
TCGAGAAATCTCTTCTTGCAGCAACTTCGAAGCGTTCCAGGCGAGACGTGCGAATATTCGTTTCAGACGTGAAGCGAAAG
GCAAGCCTGAGCATGTACACACACTGAACGGCTCAGGACTGGCGGTTGGAAGAACAGTTGCTGCTATCTTAGAAAATTAT
CAGCAGGAAGACGGAAGCGTTGTGATTCCGAAAGTGCTTCGTCCTTATATGGGGAATAGAGAAGTAATGAAACCGTAA

Protein sequence :
MLDTKMLRANFQEIKAKLVHKGEDLTDFDKFEALDDRRRELIGKVEELKGKRNEVSQQVAVLKREKKDADHIIKEMREVG
EEIKKLDEELRTVEAELDTILLSIPNIPHESVPVGETEDDNVEVRKWGEKPSFAYEPKPHWDIADELGILDFERAAKVTG
SRFVFYKGLGARLERALYNFMLDLHVDEYNYTEVIPPYMVNRASMTGTGQLPKFEEDAFKIREEDYFLIPTAEVPITNMH
RDEILSGDSLPINYAAFSACFRSEAGSAGRDTRGLIRQHQFNKVELVKFVKPEDSYEELEKLTNQAERVLQLLELPYRVM
SMCTGDLGFTAAKKYDIEVWIPSQDTYREISSCSNFEAFQARRANIRFRREAKGKPEHVHTLNGSGLAVGRTVAAILENY
QQEDGSVVIPKVLRPYMGNREVMKP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-134 63