Gene Information

Name : zosA (BSU13850)
Accession : NP_389268.1
Strain : Bacillus subtilis 168
Genome accession: NC_000964
Putative virulence/resistance : Resistance
Product : zinc-transporting ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 1451371 - 1453284 bp
Length : 1914 bp
Strand : +
Note : Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029044, 12180919, 15802251; Product type t: transporter

DNA sequence :
ATGAATGAACAAGTTATCGTTCAACGCGACCCGCATGAGCCATTGAAAACAGACAAGAGGGAAAAAAACTGGGCACAGCA
CGCGGAGCTTATTGCAGCACTTGTATCAGGCGCTCTTATTTTGGCAGGCTGGCTCTTATCCGGATATCAGGTATTATCCA
TAATACTTTTCTTGCTGGCTTTTGTGATCGGCGGATTTGCTAAAGCGAAGGAAGGAATCGAAGAAACACTCGAATCCAAA
ACGCTGAATGTAGAACTTTTAATGATTTTCGCTGCCATTGGTTCCGCCTTGATCGGATACTGGGCAGAGGGTGCTATTTT
AATATTTATTTTTTCCTTAAGCGGAGCTTTAGAAACATACACGATGAATAAAAGCAGCAGAGATTTAACGTCTTTAATGC
AGCTTGAGCCTGAAGAAGCGACATTGATGGTCAATGGTGAAACCAAAAGAGTTCCGGTTTCAGACTTGCAGGCCGGTGAT
ATGATTGTGATCAAACCTGGAGAACGCGTAGCGGCAGACGGTATCATTGAATCGGGCTCGACAAGTCTTGACGAGTCGGC
TTTAACAGGTGAATCAATGCCTGTAGAAAAAAACACAGGCGACACTGTATTCACAGGAACGGTGAATCGCAATGGCTCCT
TGACAGTCCGTGTCACGAAAGCAAATGAAGATTCGTTATTCAGAAAAATTATCAAACTGGTTGAATCAGCGCAAAATAGT
GTTTCACCCGCGCAGGCTTTCATCGAACGATTTGAAAATGCTTATGTGAAAGGTGTGCTAATTGCGGTGGCGCTCCTTTT
ATTCGTCCCGCACTTTGCGCTGGGCTGGAGCTGGAGTGAAACCTTCTACCGCGCAATGGTGTTTATGGTTGTCGCGTCAC
CTTGTGCGCTTGTCGCCTCTATTATGCCGGCGGCGCTGTCCCTGATTTCAAATGGCGCCCGCAACGGTATGCTTGTGAAA
GGAAGCGTCTTTCTTGAACAGCTGGGCTCAGTGCAAATGATCGCCTTTGATAAAACCGGAACTGTAACAAAAGGCCAGCC
TGCCGTAGAGACGATCAGAATAGCAGAAGGATTCAGTGAAGCGGAAGTTCTTGAGGCTGTCTATGCCATCGAAACGCAAT
CAAGCCATCCGCTCGCCCAAGCCATAACGGCGTACGCTGAAAGCCGCGGCGTGAATCAGTCCGGCTACATATCTATAGAA
GAAACCTCAGGGTTTGGCGTTATGGCAGAAGTGTCGGGTGCGAAATGGAAGGTCGGTAAAGCAGGTTTTATCGGCGAGGA
AATGGCAGCACAATTTATGAAACAAACAGCATCAGATGTCATTCAAAGCGGTCATACAATTGTATTTGTGAAAAAGGATG
ATCAAATAGCAGGCTGTATCGCACTGAAGGACCAAATCAGGCCTGAAGCAAAAGAGGTCATGGAAGAACTGAACCGACTT
GGGATTAAAACGGCCATGCTGACAGGAGATCACGAAGACACGGCTCAAGCGATTGCCAAGGAAGCCGGCATGACAACTGT
CGTGGCAGAATGCCTGCCTGACCAAAAAGTGAATGAAATCAAACGGTTAAAAGAAGAATTCGGAACGATTGCAATGGTGG
GTGACGGAATCAATGATGCGCCGGCACTCAAAGCAGCGGATGTCGGCATTGCGATGGGCGGCGGAACAGATGTAGCACTT
GAGACCGCTGATATGGTCCTCATGAAAAACGATTTGAAAAAGCTCGTAAACATGTGCCGCTTGTCTCGGAAAATGAACAG
GATCATCAAACAAAATATCGTGTTTTCTCTAGCTGTAATCTGCCTGCTGATTTGTGCAAACTTTTTGCAGGCGATGGAAT
TGCCATTTGGCGTGATTGGTCATGAGGGCAGCACGATTTTAGTCATACTAAACGGTTTAAGACTCCTAAAATAA

Protein sequence :
MNEQVIVQRDPHEPLKTDKREKNWAQHAELIAALVSGALILAGWLLSGYQVLSIILFLLAFVIGGFAKAKEGIEETLESK
TLNVELLMIFAAIGSALIGYWAEGAILIFIFSLSGALETYTMNKSSRDLTSLMQLEPEEATLMVNGETKRVPVSDLQAGD
MIVIKPGERVAADGIIESGSTSLDESALTGESMPVEKNTGDTVFTGTVNRNGSLTVRVTKANEDSLFRKIIKLVESAQNS
VSPAQAFIERFENAYVKGVLIAVALLLFVPHFALGWSWSETFYRAMVFMVVASPCALVASIMPAALSLISNGARNGMLVK
GSVFLEQLGSVQMIAFDKTGTVTKGQPAVETIRIAEGFSEAEVLEAVYAIETQSSHPLAQAITAYAESRGVNQSGYISIE
ETSGFGVMAEVSGAKWKVGKAGFIGEEMAAQFMKQTASDVIQSGHTIVFVKKDDQIAGCIALKDQIRPEAKEVMEELNRL
GIKTAMLTGDHEDTAQAIAKEAGMTTVVAECLPDQKVNEIKRLKEEFGTIAMVGDGINDAPALKAADVGIAMGGGTDVAL
ETADMVLMKNDLKKLVNMCRLSRKMNRIIKQNIVFSLAVICLLICANFLQAMELPFGVIGHEGSTILVILNGLRLLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA YP_005732869.1 cadmium-translocating P-type ATPase Not tested Type-V SCCmec Protein 4e-109 43
SE0062 NP_763617.1 copper-transporting ATPase copA Not tested SCCpbp4 Protein 3e-109 43
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-96 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
zosA NP_389268.1 zinc-transporting ATPase BAC0092 Protein 8e-129 45
zosA NP_389268.1 zinc-transporting ATPase BAC0099 Protein 7e-96 41