Gene Information

Name : RP783 (RP783)
Accession : NP_221133.1
Strain : Rickettsia prowazekii Madrid E
Genome accession: NC_000963
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 981490 - 982767 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAAATATCAAATGGATTAGAGAAAATCAAGAATTATTCGATGAAAAACTGAGTCAAAGATTTATTGAACCTATGTC
TAGTAAAATTGCTATGCTCGACCAAGAAAAAAGGAAAATTACGAGTTTAATTCAAGAATTTCAGCATGCACGTAAGGTAA
AATCAAAGATTTTAGGTAATATGGTCTCTAAAAGTGGCGAAGAGTTTGAAGAATTACAAAGAGATGTAAACCATATAAAT
GAGAAGTTAGCAGAACTTGAACAGAATCTAGATAATAATAACGAATTAAATGAACTATTAAATATGCTACCTAATATTCC
GGACGAGGAAGTACCTTACGGGATCGATGGAAGTATGAATAAGTTAGTACGTGCTTACGGCAAGACAAATAAAAATGCTT
TGAATAAACAGCATTTTGAATTAGGTACAAAATTAAATTTAATGGATTTTGAACAAACAGCTAAAATTTCTGGATCTAGA
TTTGTAACATTAAAAGGTGATTTAGCAAAGCTAGAACGTGCTTTAATTAATTTTATGATTGACATTCATACTAAAGAGTT
TGACTTCTTTGAGATATCACCTCCGTTCTTAGTTCGAGATAGGGCTATGTATAATGCAGGACAACTACCTAAGTTTTCTG
AAGAGTCTTTTATAACAACAAATGGGTACAGACTAATTCCAACTGCAGAAGTATCTTTAGTAAATATAGTCGCCGATACT
ATTATACAAAGAGAAAAATTACCTATGCGTTACGTTGCTTACACCACATGTTTTAGATCAGAAGCAGGTAGTAGCGGTAG
AGATACAAGAGGGATGATTAGATTACATCAGTTTGGTAAAGTCGAACTCGTATCTATTACTACCCCTGAAGAATCAAAAA
ATGAGCATGAATATATAACTAATGCATCAGAGACTATTTTAAAAAAACTCGATCTTCCGTATCGTGTTATGCTACTTTGT
ACTGGCGATATGGGATTTGCAGCAAAAAAAACTTATGATATAGAAGTATGGCTTCCTGGGCAAAATCAATATCGTGAAAT
TGCTAGCTGTTCTAATTGTGGAGATTTTCAAGCACGTAGAATGAAAGCAAGATATAAGGAATTTGGTAGTAATGAAACTA
CATTAGTACATACTTTAAATGCTTCAGGATTACCTATCGGTAGAACTATAGTTGCAATACTTGAAAATTATCAGAATAAC
GATGGATCAATAACTATACCTGACGTCTTAATAAATTACATGGGCGGGTTACAAAAAATTACTACATATAGCGAATAA

Protein sequence :
MLNIKWIRENQELFDEKLSQRFIEPMSSKIAMLDQEKRKITSLIQEFQHARKVKSKILGNMVSKSGEEFEELQRDVNHIN
EKLAELEQNLDNNNELNELLNMLPNIPDEEVPYGIDGSMNKLVRAYGKTNKNALNKQHFELGTKLNLMDFEQTAKISGSR
FVTLKGDLAKLERALINFMIDIHTKEFDFFEISPPFLVRDRAMYNAGQLPKFSEESFITTNGYRLIPTAEVSLVNIVADT
IIQREKLPMRYVAYTTCFRSEAGSSGRDTRGMIRLHQFGKVELVSITTPEESKNEHEYITNASETILKKLDLPYRVMLLC
TGDMGFAAKKTYDIEVWLPGQNQYREIASCSNCGDFQARRMKARYKEFGSNETTLVHTLNASGLPIGRTIVAILENYQNN
DGSITIPDVLINYMGGLQKITTYSE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 7e-78 44