Gene Information

Name : rph (RP628)
Accession : NP_220993.1
Strain : Rickettsia prowazekii Madrid E
Genome accession: NC_000963
Putative virulence/resistance : Unknown
Product : ribonuclease PH
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0689
EC number : 2.7.7.56
Position : 801830 - 802552 bp
Length : 723 bp
Strand : -
Note : RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs

DNA sequence :
ATGAGACAGTCAGGAAGAAAAAGCAACCAATTACGTCCTATTTCATTAGAATTATCTCCTCTGATTAATGCAGAAGGATC
ATGTCTGATTAAAATCGGTAATACGCATGTAATGTGTAGTGCTACTTGTGAAACTACTGTGCCTCCATTCTTAAGGGGGC
AAAATCAAGGATGGATTACTGCTGAGTATGGTATGATCCCAGGGTCTACATCGCATCGTATAAAAAGAGAAGCTGCACTC
GGAAAACAAGGTGGCAGAACTCAAGAGATACAGCGTTTGATAGGTAGGGCGATGCGATGTGTAATTAATTTGCAGAAACT
CGGGGAGAGACAAATTATCATAGATTGTGACGTTATTAATGCAGATGGCGGTACTAGAACTGCGGCGATAACTGGAAGCT
ATGTAGCATTGCACCTAGCTATTAGATCGTTGATGAAAAAGAGGATTTTAAAAGTGAACCCGTTAATTAGTCAAATTGCC
GCTATTTCTTGCGGTATATATAAAGGTAATGCGGTTCTAGATTTAGATTATTTAGAAGATAGTGATGCGGAAGTGGATAG
TAATTTTGTTTTTGCATGTAATGGTAATTTAATTGAAGTACAAGGGACTGCAGAGAAAGAACCATTTTCTGAAGAGCAGT
TTTTAGCAATGTTAAAACTTGCTAAAAGTGGAGTTGTAGAATTATTCAAACTACAAAATCAAGTGCTGATCGCGGCTGAA
TAA

Protein sequence :
MRQSGRKSNQLRPISLELSPLINAEGSCLIKIGNTHVMCSATCETTVPPFLRGQNQGWITAEYGMIPGSTSHRIKREAAL
GKQGGRTQEIQRLIGRAMRCVINLQKLGERQIIIDCDVINADGGTRTAAITGSYVALHLAIRSLMKKRILKVNPLISQIA
AISCGIYKGNAVLDLDYLEDSDAEVDSNFVFACNGNLIEVQGTAEKEPFSEEQFLAMLKLAKSGVVELFKLQNQVLIAAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
rph YP_001800860.1 ribonuclease PH Not tested Not named Protein 2e-48 49