Gene Information

Name : thiC (Rv0423c)
Accession : NP_214937.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Unknown
Product : Probable thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 508582 - 510225 bp
Length : 1644 bp
Strand : -
Note : Rv0423c, (MTCY22G10.20c), len: 547 aa. Probable thiC, thiamin biosynthesis protein, equivalent to Q9ZBL0|THIC_MYCLE|11279601|T44743|AL035159|MLCB1450_22 thiamine biosynthesis protein from Mycobacterium leprae (547 aa), FASTA scores: opt: 3283, E(): 0, (90

DNA sequence :
ATGACCATCACCGTTGAACCGTCGGTGACCACGGGTCCCATCGCGGGCAGCGCCAAGGCCTACCGTGAAATCGAGGCTCC
CGGCAGCGGAGCTACTCTCCAAGTCCCGTTTCGACGGGTGCACTTGTCCACCGGAGACCACTTCGACCTCTACGACACCT
CCGGGCCCTACACCGACACGGACACGGTGATCGACCTGACCGCGGGGCTGCCGCATAGGCCCGGAGTGGTTCGCGATCGG
GGCACCCAGCTGCAGCGGGCCCGCGCCGGGGAGATCACCGCCGAGATGGCGTTCATCGCCGCCCGCGAAGACATGTCCGC
CGAGCTAGTGCGCGACGAGGTCGCCCGCGGCCGCGCGGTGATCCCGGCCAACCACCACCACCCCGAGAGCGAGCCGATGA
TCATCGGCAAGGCGTTCGCGGTGAAAGTCAACGCCAACATCGGCAACTCGGCGGTGACGAGCTCGATCGCCGAGGAGGTC
GACAAGATGGTGTGGGCCACCCGCTGGGGGGCCGACACCATCATGGACCTGTCCACCGGCAAGAACATCCACGAAACCCG
CGAGTGGATCCTGCGCAATTCTCCCGTGCCGGTCGGCACCGTGCCGATCTATCAGGCGCTGGAGAAAGTCAAGGGCGATC
CGACCGAGCTGACCTGGGAGATCTACCGCGACACCGTGATCGAGCAGTGTGAGCAAGGCGTGGACTACATGACGGTGCAC
GCCGGGGTGCTGCTGCGGTATGTGCCGCTGACCGCCAAGCGGGTCACCGGCATCGTGTCCCGCGGGGGTTCGATCATGGC
CGCGTGGTGTTTGGCACATCATCGGGAGTCGTTCTTGTACACCAACTTTGAGGAGCTCTGCGATATTTTCGCCCGCTACG
ACGTCACCTTCTCACTCGGTGACGGGCTGCGACCAGGGTCGATCGCTGATGCCAACGACGCCGCGCAGTTCGCCGAGCTG
CGCACCCTGGGCGAGCTCACCAAGATCGCCAAAGCCCATGGCGCACAGGTGATGATCGAGGGGCCGGGCCATATCCCAAT
GCACAAGATCGTCGAGAATGTGCGGCTGGAAGAGGAACTGTGTGAGGAGGCCCCGTTCTACACGCTGGGTCCGCTGGCCA
CCGACATCGCGCCGGCCTACGACCACATCACCTCGGCGATCGGTGCGGCCATCATCGCCCAAGCCGGTACCGCGATGCTG
TGCTACGTCACCCCCAAGGAGCACCTCGGGTTGCCGGACCGCAAGGACGTCAAGGACGGGGTGATCGCCTACAAGATCGC
CGCGCATGCGGCCGATTTGGCCAAGGGCCATCCGCGCGCCCAGGAGCGCGACGACGCTTTGAGCACGGCGCGTTTCGAGT
TCCGCTGGAACGACCAGTTCGCACTGTCGCTGGATCCCGACACCGCACGGGAATTCCACGACGAAACCCTGCCGGCGGAG
CCGGCCAAGACCGCGCACTTCTGCTCGATGTGCGGACCGAAGTTCTGCTCCATGCGCATCACCCAGGACGTCCGTGAGTA
CGCCGCCGAACACGGGCTTGAGACCGAAGCGGACATCGAAGCCGTGCTCGCCGCCGGAATGGCCGAAAAGTCACGTGAAT
TCGCAGAGCACGGCAATCGGGTGTATCTCCCGATAACCCAGTGA

Protein sequence :
MTITVEPSVTTGPIAGSAKAYREIEAPGSGATLQVPFRRVHLSTGDHFDLYDTSGPYTDTDTVIDLTAGLPHRPGVVRDR
GTQLQRARAGEITAEMAFIAAREDMSAELVRDEVARGRAVIPANHHHPESEPMIIGKAFAVKVNANIGNSAVTSSIAEEV
DKMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTELTWEIYRDTVIEQCEQGVDYMTVH
AGVLLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFEELCDIFARYDVTFSLGDGLRPGSIADANDAAQFAEL
RTLGELTKIAKAHGAQVMIEGPGHIPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAML
CYVTPKEHLGLPDRKDVKDGVIAYKIAAHAADLAKGHPRAQERDDALSTARFEFRWNDQFALSLDPDTAREFHDETLPAE
PAKTAHFCSMCGPKFCSMRITQDVREYAAEHGLETEADIEAVLAAGMAEKSREFAEHGNRVYLPITQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 4e-155 68
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 4e-155 68