Gene Information

Name : trxB2 (Rv3913)
Accession : NP_218430.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Unknown
Product : Probable thioredoxin reductase TrxB2 (TRXR) (TR)
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0492
EC number : -
Position : 4401728 - 4402735 bp
Length : 1008 bp
Strand : +
Note : Rv3913, (MT4032, MTV028.04), len: 335 aa. Probable trxB2, thioredoxin reductase (see citation below),equivalent to O30973|TRXB_MYCSM thioredoxin reductase from Mycobacterium smegmatis (311 aa), FASTA scores: opt: 1575,E(): 1.8e-87, (78.35% identity in 305

DNA sequence :
ATGACCGCCCCGCCTGTCCATGACCGCGCACACCACCCCGTTCGCGACGTGATCGTTATCGGCTCCGGTCCCGCGGGGTA
CACTGCGGCGCTCTACGCCGCCCGTGCCCAGCTGGCGCCGCTGGTCTTCGAGGGCACGTCTTTCGGCGGCGCGCTGATGA
CCACCACCGACGTGGAGAACTACCCGGGATTTCGCAACGGCATCACCGGTCCAGAGTTGATGGATGAGATGCGGGAACAG
GCGCTGCGATTCGGCGCGGACCTGCGTATGGAAGACGTCGAGTCGGTATCACTTCACGGGCCGCTGAAATCGGTCGTCAC
CGCCGACGGACAGACCCACCGGGCCCGAGCCGTGATCCTGGCAATGGGCGCAGCGGCACGCTATCTGCAGGTGCCCGGCG
AACAGGAATTGCTCGGGCGCGGGGTGAGCTCGTGCGCCACCTGCGACGGATTCTTCTTCCGCGATCAGGACATCGCCGTC
ATCGGCGGCGGTGACTCGGCAATGGAGGAAGCTACCTTCCTGACCCGATTCGCTCGCAGTGTGACGCTGGTGCATCGCCG
CGACGAGTTCCGGGCTTCCAAAATCATGCTCGATCGCGCCCGCAACAACGACAAGATACGGTTCCTCACCAACCACACCG
TGGTCGCGGTGGACGGGGACACCACAGTGACCGGCTTGCGGGTACGCGACACCAACACCGGTGCCGAAACCACCCTGCCG
GTAACCGGTGTTTTCGTCGCGATCGGCCACGAGCCGCGGTCGGGCTTGGTGCGCGAGGCCATCGACGTCGACCCGGACGG
CTACGTGTTGGTGCAGGGGCGTACCACCAGCACCTCACTGCCGGGCGTGTTCGCTGCCGGCGACCTGGTGGATCGCACCT
ATCGCCAGGCGGTTACCGCAGCGGGCAGTGGCTGCGCCGCGGCTATCGACGCCGAGCGCTGGCTCGCCGAGCACGCAGCA
ACCGGAGAAGCTGACAGTACCGACGCATTGATAGGAGCACAACGATGA

Protein sequence :
MTAPPVHDRAHHPVRDVIVIGSGPAGYTAALYAARAQLAPLVFEGTSFGGALMTTTDVENYPGFRNGITGPELMDEMREQ
ALRFGADLRMEDVESVSLHGPLKSVVTADGQTHRARAVILAMGAAARYLQVPGEQELLGRGVSSCATCDGFFFRDQDIAV
IGGGDSAMEEATFLTRFARSVTLVHRRDEFRASKIMLDRARNNDKIRFLTNHTVVAVDGDTTVTGLRVRDTNTGAETTLP
VTGVFVAIGHEPRSGLVREAIDVDPDGYVLVQGRTTSTSLPGVFAAGDLVDRTYRQAVTAAGSGCAAAIDAERWLAEHAA
TGEADSTDALIGAQR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
trxB AFC76431.1 TrxB Not tested AbaR5 Protein 8e-44 42
trxB CAJ77014.1 thioredoxin reductase Not tested AbaR1 Protein 6e-44 42