Gene Information

Name : asd (Rv3708c)
Accession : NP_218225.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Unknown
Product : Aspartate-semialdehyde dehydrogenase Asd (ASA dehydrogenase) (ASADH) (aspartic semialdehyde dehydrogenase) (L-aspartate-beta-semialdehyde dehydrogenase)
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0136
EC number : -
Position : 4151180 - 4152217 bp
Length : 1038 bp
Strand : -
Note : Rv3708c, (MTV025.056c), len: 345 aa. Asd,aspartate-semialdehyde dehydrogenase (see citation below),equivalent to many e.g. P47730|DHAS_MYCBO|ASD from Mycobacterium bovis (345 aa) FASTA scores: opt: 2150, E(): 1.6e-124, (97.7% identity in 345 aa overlap);

DNA sequence : 
ATGGGCCTGTCAATAGGGATCGTGGGGGCCACCGGTCAGGTGGGTCAGGTCATGCGCACGTTGCTCGACGAGCGGGATTT
CCCGGCGAGCGCGGTGCGGTTCTTCGCGTCGGCCCGATCGCAGGGCCGCAAGCTGGCCTTCCGCGGCCAGGAGATCGAAG
TGGAAGACGCCGAGACGGCCGACCCGAGCGGGCTGGATATCGCGTTGTTCTCCGCCGGCTCGGCCATGTCGAAGGTGCAG
GCGCCCCGCTTTGCGGCGGCCGGAGTCACGGTGATCGACAACTCGTCGGCGTGGCGTAAGGACCCCGACGTGCCGTTGGT
GGTGTCCGAGGTGAACTTTGAACGCGACGCGCACCGCCGGCCTAAGGGCATCATCGCCAACCCGAACTGCACCACCATGG
CCGCGATGCCGGTGCTCAAGGTGCTGCACGACGAAGCCCGACTGGTGCGGTTGGTGGTCTCGTCGTATCAGGCGGTGTCC
GGTAGCGGCCTGGCCGGGGTGGCCGAGCTGGCCGAGCAGGCGCGTGCGGTCATCGGTGGGGCCGAGCAGCTGGTGTATGA
CGGCGGCGCGCTCGAGTTCCCGCCGCCGAACACCTACGTCGCCCCGATCGCGTTCAACGTGGTGCCGCTGGCCGGATCCC
TGGTGGACGACGGCTCCGGCGAGACAGACGAGGATCAAAAGTTGCGCTTCGAGAGCCGCAAGATCCTTGGCATCCCCGAC
CTGTTGGTCAGCGGCACCTGTGTGCGGGTTCCGGTGTTCACCGGACACTCTTTGTCGATCAACGCCGAGTTCGCGCAGCC
GCTCTCGCCGGAGCGGGCGCGCGAGCTGCTCGACGGTGCTACGGGCGTGCAGCTGGTCGACGTGCCGACGCCGCTGGCCG
CCGCCGGTGTCGACGAATCTCTGGTCGGCCGGATCCGGCGCGACCCGGGGGTGCCCGACGGGCGTGGTCTGGCGCTGTTC
GTGTCGGGGGATAACCTGCGCAAGGGGGCGGCGCTGAACACCATCCAGATCGCCGAGCTGCTGACCGCCGACTTGTGA

Protein sequence : 
MGLSIGIVGATGQVGQVMRTLLDERDFPASAVRFFASARSQGRKLAFRGQEIEVEDAETADPSGLDIALFSAGSAMSKVQ
APRFAAAGVTVIDNSSAWRKDPDVPLVVSEVNFERDAHRRPKGIIANPNCTTMAAMPVLKVLHDEARLVRLVVSSYQAVS
GSGLAGVAELAEQARAVIGGAEQLVYDGGALEFPPPNTYVAPIAFNVVPLAGSLVDDGSGETDEDQKLRFESRKILGIPD
LLVSGTCVRVPVFTGHSLSINAEFAQPLSPERARELLDGATGVQLVDVPTPLAAAGVDESLVGRIRRDPGVPDGRGLALF
VSGDNLRKGAALNTIQIAELLTADL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
CDB402_0195 YP_005126708.1 aspartate-semialdehyde dehydrogenase Not tested Not named Protein 7e-92 65