Gene Information

Name : glpK (Rv3696c)
Accession : NP_218213.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Unknown
Product : Probable glycerol kinase GlpK (ATP:glycerol 3-phosphotransferase) (glycerokinase) (GK)
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG0554
EC number : -
Position : 4138202 - 4139755 bp
Length : 1554 bp
Strand : -
Note : Rv3696c, (MTV025.044c), len: 517 aa. Probable glpK,glycerol kinase, equivalent to Q9CB81|GLPK_MYCLE|ML2314 glycerol kinase from Mycobacterium leprae (508 aa), FASTA scores: opt: 3120, E(): 4.7e-189, (91.35% identity in 508 aa overlap). Also highly similar

DNA sequence :
GTGTCCGACGCCATCCTAGGAGAGCAATTGGCCGAGTCCTCGGATTTCATAGCCGCCATCGACCAGGGCACCACCAGCAC
CCGCTGCATGATCTTCGATCACCACGGTGCCGAGGTGGCCCGCCACCAGCTCGAGCACGAGCAGATCCTGCCCCGGGCCG
GCTGGGTGGAGCACAACCCGGTCGAGATCTGGGAGCGCACCGCGTCGGTGTTGATCTCGGTGCTCAACGCCACCAACCTA
TCGCCGAAAGATATTGCCGCGTTGGGGATTACCAACCAACGTGAGACGACGCTGGTATGGAATCGGCACACCGGACGGCC
CTACTACAACGCGATTGTATGGCAGGATACCCGCACCGACCGCATCGCGTCGGCGCTGGATCGAGACGGTCGTGGAAACC
TGATCCGCCGCAAGGCGGGCCTGCCGCCGGCAACTTATTTCTCTGGCGGCAAGCTGCAGTGGATCCTGGAAAATGTCGAT
GGAGTCCGCGCGGCCGCCGAGAACGGCGACGCATTGTTCGGCACACCGGACACCTGGGTGTTGTGGAATCTGACCGGCGG
GCCGCGGGGGGGTGTGCATGTCACCGATGTAACCAACGCCAGCCGGACCATGTTGATGGATCTAGAGACGCTGGACTGGG
ACGACGAGCTGTTGTCGTTGTTTTCGATACCTCGGGCCATGCTGCCCGAGATCGCATCGTCGGCGCCGTCGGAGCCTTAC
GGTGTCACGCTGGCGACCGGGCCTGTCGGCGGTGAGGTGCCGATCACCGGAGTTCTCGGTGATCAGCATGCGGCCATGGT
CGGTCAAGTCTGTCTGGCCCCAGGGGAGGCGAAAAACACCTATGGGACCGGCAATTTTCTGCTGCTGAACACCGGTGAAA
CGATCGTGCGATCGAATAACGGCCTGCTAACCACGGTGTGCTACCAATTCGGGAACGCTAAACCCGTGTACGCGCTTGAA
GGTTCGATCGCGGTGACCGGCTCGGCGGTGCAGTGGCTACGCGATCAGCTGGGCATCATCAGCGGCGCCGCACAGAGTGA
GGCGCTGGCCCGCCAGGTCCCCGACAACGGCGGCATGTATTTCGTGCCGGCGTTTTCCGGGCTGTTCGCGCCATACTGGC
GGTCCGATGCGCGCGGCGCGATCGTCGGGTTGTCGCGGTTCAACACCAACGCGCACCTGGCGCGCGCAACGCTGGAGGCG
ATCTGCTACCAGAGCCGCGATGTGGTGGACGCCATGGAAGCAGACTCCGGTGTTCGCCTGCAGGTGTTGAAGGTGGATGG
CGGGATCACCGGCAACGACCTGTGTATGCAGATCCAGGCCGACGTGTTGGGTGTGGATGTGGTGCGGCCGGTGGTCGCCG
AGACCACCGCACTAGGTGTGGCCTACGCGGCGGGCTTGGCGGTCGGGTTCTGGGCGGCTCCGTCCGATCTGCGGGCCAAC
TGGCGAGAGGACAAGCGGTGGACACCGACGTGGGACGACGACGAGCGTGCCGCGGGTTATGCCGGCTGGCGCAAGGCGGT
GCAGCGGACCCTGGATTGGGTTGACGTGTCCTAG

Protein sequence :
MSDAILGEQLAESSDFIAAIDQGTTSTRCMIFDHHGAEVARHQLEHEQILPRAGWVEHNPVEIWERTASVLISVLNATNL
SPKDIAALGITNQRETTLVWNRHTGRPYYNAIVWQDTRTDRIASALDRDGRGNLIRRKAGLPPATYFSGGKLQWILENVD
GVRAAAENGDALFGTPDTWVLWNLTGGPRGGVHVTDVTNASRTMLMDLETLDWDDELLSLFSIPRAMLPEIASSAPSEPY
GVTLATGPVGGEVPITGVLGDQHAAMVGQVCLAPGEAKNTYGTGNFLLLNTGETIVRSNNGLLTTVCYQFGNAKPVYALE
GSIAVTGSAVQWLRDQLGIISGAAQSEALARQVPDNGGMYFVPAFSGLFAPYWRSDARGAIVGLSRFNTNAHLARATLEA
ICYQSRDVVDAMEADSGVRLQVLKVDGGITGNDLCMQIQADVLGVDVVRPVVAETTALGVAYAAGLAVGFWAAPSDLRAN
WREDKRWTPTWDDDERAAGYAGWRKAVQRTLDWVDVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glpK YP_005139160.1 glycerol kinase Not tested Not named Protein 1e-113 59