Gene Information

Name : dppD (Rv3663c)
Accession : NP_218180.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Unknown
Product : Probable dipeptide-transport ATP-binding protein ABC transporter DppD
Function : -
COG functional category : R : General function prediction only
COG ID : COG1123
EC number : -
Position : 4102032 - 4103678 bp
Length : 1647 bp
Strand : -
Note : Rv3663c, (MTV025.011c), len: 548 aa. Probable dppD,dipeptide-transport ATP-binding protein ABC-transporter (see citation below), similar to many ATP-binding proteins e.g. AAK65441|SMA1434 probable ABC transporter ATP-binding protein from Rhizobium melilot

DNA sequence :
ATGAGCGTCCCAGCAGCGCCGCTGTTGTCGGTGGAGGGCCTGGAAGTTACGTTCGGCACCGATGCTCCCGCCGTGTGTGG
GGTGGATCTGGCCGTCCGGAGCGGTCAAACCGTCGCCGTGGTGGGTGAGTCCGGGTCGGGCAAATCCACGACGGCCGCGG
CGATTCTTGGGTTGCTTCCGGCTGGTGGACGGATCACCGCTGGACGCGTTGTGTTCGACGGGCGCGACATCACCGGGGCC
GATGCCAAGCGGCTACGGTCGATAAGGGGACGGGAGATCGGCTATGTTCCCCAGGATCCGATGACCAACCTCAATCCGGT
TTGGAAGGTCGGCTTTCAGGTCACAGAAGCGTTGCGGGCCAATACCGACGGTCGCGCAGCACGACGACGGGCGGTGGAGC
TACTCGCTGAGGCGGGCCTGCCGGATCCGGCGAAGCAAGCCGGACGCTACCCGCATCAGCTGTCCGGCGGCATGTGCCAG
CGGGCGTTGATTGCGATCGGCTTGGCGGGCAGGCCGCGGCTGCTGATCGCCGATGAGCCGACGTCCGCGTTGGATGTCAC
CGTGCAGCGGCAGGTGCTCGATCATCTTCAGGGACTCACCGACGAACTAGGCACCGCGCTGCTACTGATCACCCACGATC
TGGCGTTGGCCGCGCAGCGGGCCGAGGCTGTCGTCGTCGTCCGTCGTGGAGTGGTGGTGGAATCCGGTGCGGCGCAGTCA
ATCCTGCAAAGCCCTCAGCACGAGTACACCCGGCGCCTGGTGGCCGCGGCTCCATCGCTGACGGCGCGCAGCAGACGTCC
GCCGGAATCCCGGTCACGGGCAACCACGCAGGCCGGCGACATTCTCGTCGTCTCGGAGCTGACCAAGATTTACCGGGAGT
CCCGCGGCGCACCGTGGCGGCGGGTGGAGTCTCGCGCCGTCGACGGAGTGTCATTCCGGCTACCGCGGGCGAGCACCCTG
GCAATCGTCGGCGAATCCGGGTCAGGCAAGTCGACGCTAGCGCGGATGGTGCTTGGGCTGCTCCAACCTACCTCGGGCAC
GGTCGTTTTCGACGGCACCTACGACGTCGGCGCGCTGGCCCGGGACCAGGTGCTGGCCTTTCGCCGCCGGGTCCAGCCGG
TGTTCCAAAACCCATACAGCAGCCTGGATCCCATGTACTCGGTGTTTCGCGCCATCGAGGAACCGTTACGCGTCCATCAC
GTCGGTGACCGCCGGCAGCGGCAAAGGGCGGTGCGTGAGCTGGTCGATCAGGTGGCGCTGCCGTCGTCGATACTGGGCCG
GCGGCCCCGTGAGCTGTCGGGTGGTCAGCGGCAGCGGGTAGCGATCGCGCGTGCGCTGGCGCTGCGCCCGGAGGTATTGG
TGTGCGACGAAGCGGTGTCGGCGCTCGACGTATTGGTGCAGGCACAGATCCTGGATCTGCTGGCCGATCTGCAGGCCGAC
CTGGGTTTGACGTATTTGTTCATCAGCCATGATCTGGCGGTGATCCGGCAGATTGCCGACGACGTCCTGGTCATGCGGGC
CGGCCGGGTGGTGGAGCACGCCTCTACCGAGGAGGTGTTCAGCCGGCCCCGCCACGAGTACACCCGCCAGTTGCTTCAGG
CCATTCCCGGTGCCCCCTCAGCTCCCCGAAAGGTTGGCAACCTGTGA

Protein sequence :
MSVPAAPLLSVEGLEVTFGTDAPAVCGVDLAVRSGQTVAVVGESGSGKSTTAAAILGLLPAGGRITAGRVVFDGRDITGA
DAKRLRSIRGREIGYVPQDPMTNLNPVWKVGFQVTEALRANTDGRAARRRAVELLAEAGLPDPAKQAGRYPHQLSGGMCQ
RALIAIGLAGRPRLLIADEPTSALDVTVQRQVLDHLQGLTDELGTALLLITHDLALAAQRAEAVVVVRRGVVVESGAAQS
ILQSPQHEYTRRLVAAAPSLTARSRRPPESRSRATTQAGDILVVSELTKIYRESRGAPWRRVESRAVDGVSFRLPRASTL
AIVGESGSGKSTLARMVLGLLQPTSGTVVFDGTYDVGALARDQVLAFRRRVQPVFQNPYSSLDPMYSVFRAIEEPLRVHH
VGDRRQRQRAVRELVDQVALPSSILGRRPRELSGGQRQRVAIARALALRPEVLVCDEAVSALDVLVQAQILDLLADLQAD
LGLTYLFISHDLAVIRQIADDVLVMRAGRVVEHASTEEVFSRPRHEYTRQLLQAIPGAPSAPRKVGNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dppD YP_005160017.1 putative peptide ABC transport system ATP-binding protein Not tested Not named Protein 3e-118 58
oppDF2 YP_005681814.1 Oligopeptide transport ATP-binding protein OppD Not tested PiCp 6 Protein 3e-55 41
oppDF2 YP_005683914.1 Oligopeptide transport ATP-binding protein OppD Not tested PiCp 6 Protein 3e-55 41
cpfrc_01561 YP_003783961.1 hypothetical protein Not tested PiCp 6 Protein 3e-55 41
oppDF2 YP_005686002.1 Oligopeptide transport ATP-binding protein OppD Not tested PiCp 6 Protein 3e-55 41