Gene Information

Name : lysS (Rv3598c)
Accession : NP_218115.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Unknown
Product : Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase)
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 4041423 - 4042940 bp
Length : 1518 bp
Strand : -
Note : Rv3598c, (MTCY07H7B.24), len: 505 aa. Probable lysS,lysyl-tRNA synthetase 1, equivalent to P46861|SYK_MYCLE|LYSS|ML0233 lysyl-tRNA synthetase from Mycobacterium leprae (507 aa), FASTA scores: opt: 2835,E(): 4.5e-172, (85.45% identity in 501 aa overlap); a

DNA sequence :
GTGAGTGCCGCTGACACAGCAGAAGACCTTCCTGAGCAGTTCCGGATTCGCCGGGACAAGCGCGCTCGCTTGCTGGCCCA
GGGGCGCGATCCCTATCCCGTCGCGGTGCCGCGCACTCACACGTTGGCCGAGGTTCGCGCCGCCCACCCTGACTTGCCGA
TCGATACCGCGACCGAAGACATCGTCGGCGTCGCGGGCCGAGTGATCTTTGCGCGCAACTCGGGAAAGCTATGCTTTGCG
ACACTTCAGGACGGCGATGGTACCCAGCTGCAAGTGATGATCAGCCTCGACAAGGTCGGCCAGGCTGCTCTCGACGCATG
GAAAGCCGATGTCGACCTGGGCGACATCGTCTACGTGCATGGCGCGGTGATCAGTTCGCGCCGCGGCGAGCTGTCCGTCC
TGGCGGATTGCTGGCGGATCGCCGCCAAGTCGCTGCGGCCGCTTCCCGTCGCGCACAAAGAGATGAGTGAAGAGTCGCGG
GTTCGTCAGCGCTATGTTGACCTCATAGTTCGACCGGAAGCGCGCGCGGTGGCTCGACTACGGATCGCCGTCGTCCGCGC
GATCCGGACGGCGCTTCAACGTCGTGGGTTCCTGGAAGTCGAGACGCCCGTCTTGCAGACGTTAGCCGGTGGTGCGGCGG
CCCGTCCGTTCGCCACTCATTCCAATGCCCTAGACATCGATCTGTACCTGCGGATCGCGCCGGAACTGTTCCTCAAGCGC
TGCATCGTGGGTGGTTTCGACAAGGTCTTCGAACTTAATCGAGTGTTCCGAAACGAAGGAGCCGATTCCACGCATTCTCC
GGAATTCTCCATGCTGGAGACCTACCAGACCTACGGAACCTATGACGATTCGGCAGTCGTCACCCGGGAGCTTATTCAAG
AGGTGGCCGATGAGGCGATCGGAACCAGACAACTGCCGTTGCCCGACGGCAGTGTCTATGACATCGACGGAGAATGGGCG
ACTATACAAATGTACCCGTCGCTGTCTGTGGCGCTCGGTGAAGAGATCACACCGCAGACGACGGTCGATCGCTTACGTGG
GATCGCCGATAGCCTTGGCCTGGAGAAAGACCCAGCGATTCATGACAACCGTGGCTTCGGCCACGGCAAACTCATCGAGG
AACTCTGGGAGCGCACAGTGGGCAAGAGCTTGAGCGCACCCACATTTGTCAAGGATTTTCCGGTTCAGACAACGCCTTTG
ACCCGTCAGCACCGCAGTATCCCCGGCGTAACCGAGAAGTGGGACCTCTATCTGCGCGGAATCGAACTTGCCACCGGCTA
CTCGGAATTAAGCGACCCGGTAGTCCAGCGGGAGAGATTCGCCGACCAGGCCCGTGCCGCGGCCGCTGGCGATGACGAAG
CGATGGTGCTTGACGAGGATTTTCTGGCCGCTCTGGAGTACGGCATGCCACCGTGCACCGGAACCGGAATGGGTATCGAT
CGGTTGTTGATGTCTTTGACTGGGTTGTCAATTAGGGAGACAGTTTTGTTCCCGATTGTTCGACCACACTCCAACTGA

Protein sequence :
MSAADTAEDLPEQFRIRRDKRARLLAQGRDPYPVAVPRTHTLAEVRAAHPDLPIDTATEDIVGVAGRVIFARNSGKLCFA
TLQDGDGTQLQVMISLDKVGQAALDAWKADVDLGDIVYVHGAVISSRRGELSVLADCWRIAAKSLRPLPVAHKEMSEESR
VRQRYVDLIVRPEARAVARLRIAVVRAIRTALQRRGFLEVETPVLQTLAGGAAARPFATHSNALDIDLYLRIAPELFLKR
CIVGGFDKVFELNRVFRNEGADSTHSPEFSMLETYQTYGTYDDSAVVTRELIQEVADEAIGTRQLPLPDGSVYDIDGEWA
TIQMYPSLSVALGEEITPQTTVDRLRGIADSLGLEKDPAIHDNRGFGHGKLIEELWERTVGKSLSAPTFVKDFPVQTTPL
TRQHRSIPGVTEKWDLYLRGIELATGYSELSDPVVQRERFADQARAAAAGDDEAMVLDEDFLAALEYGMPPCTGTGMGID
RLLMSLTGLSIRETVLFPIVRPHSN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 6e-142 61