Gene Information

Name : hsaE (Rv3536c)
Accession : NP_218053.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Unknown
Product : Probable hydratase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG3971
EC number : -
Position : 3974511 - 3975296 bp
Length : 786 bp
Strand : -
Note : Rv3536c, (MTCY03C7.20), len: 261 aa. Probable hsaE,hydratase, 2-oxo-hepta-3-ene-1,7-dioate hydratase or 2-keto-4-pentenoate hydratase. Indeed, highly similar to many 2-oxo-hepta-3-ene-1,7-dioate hydratases e.g. Q9CKS2|HPAH|PM1534 from Pasteurella multocid

DNA sequence :
ATGCTCCGTGATGCCACCCGTGATGAGCTGGCCGCCGACCTAGCACAAGCCGAGCGAAGCCGCGACCCGATCGGTCAACT
GACCGCCGCCCATCCCGAGATCGATGTCGTCGACGCCTACGAGATCCAGTTGATCAACATCCGGCAGCGGGTGGCCGAGG
GTGCCCGCGTGGTGGGTCATAAGGTCGGGCTGTCGTCGCCGATCATGCAGCAGATGATGGGGGTTGACGAACCAGACTAC
GGACACCTGCTCGACGACATGCAGGTGTTCGAAGACACGCCGGTCCAGGCGTCCCGGTACCTGTCTCCGCGGGTTGAGGT
GGAGGTGGGCTTCATCCTGGCCGCCGACCTACCGGGTGCGGGCTGCACCGAGGACGACGTGCTGGCGGCCACCGAGGCCC
TGGTGCCCGCCATCGAGCTGATCGACACCAGGATCAAGGATTGGCAGATCAAGATCTGCGACACCATCGCCGACAACGCC
TCGGCGGCGGGCTTCGTGTTGGGCGCGGCCCGGGTGCCGCCGGCCGATCTTGACGTCAGGGCGATCGATGCGAAGCTGAC
CCGCAACGGCGAGGTGGTGGCCGAGGGCCGCAGTGATGCGGTGTTGGGTAACCCGGCGACCGCGGTGGCTTGGCTGGCCG
GCAAGGTCGAGAGTTTCGGCGTGCGGCTGCGCAAAGGCGACATCGTGTTACCCGGGTCATGCACGTTCGCGGTCGAGGCG
CGGGCCGGCGACGAGTTTGTCGCCGACTTCACCGGGCTGGGTTTGGTCCGGTTGTCGTTCGAATAA

Protein sequence :
MLRDATRDELAADLAQAERSRDPIGQLTAAHPEIDVVDAYEIQLINIRQRVAEGARVVGHKVGLSSPIMQQMMGVDEPDY
GHLLDDMQVFEDTPVQASRYLSPRVEVEVGFILAADLPGAGCTEDDVLAATEALVPAIELIDTRIKDWQIKICDTIADNA
SAAGFVLGAARVPPADLDVRAIDAKLTRNGEVVAEGRSDAVLGNPATAVAWLAGKVESFGVRLRKGDIVLPGSCTFAVEA
RAGDEFVADFTGLGLVRLSFE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaH AAO17184.1 HpaH Not tested tcd island Protein 1e-42 43