Gene Information

Name : Rv3475 (Rv3475)
Accession : NP_217992.2
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Unknown
Product : Possible transposase for insertion element IS6110 [second part]
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3891105 - 3892091 bp
Length : 987 bp
Strand : +
Note : Rv3475, (MTCY13E12.28), len: 328 aa. Probable transposase subunit for IS6110. Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation that fuses Rv347

DNA sequence : 
AAAGACCGCGTCGGCTTTCTTCGCGGCCGAGCTCGACCGGCCAGCACGCTAATTACCCGGTTCATCGCCGATCATCAGGG
CCACCGCGAGGGCCCCGATGGTTTGCGGTGGGGTGTCGAGTCGATCTGCACACAGCTGACCGAGCTGGGTGTGCCGATCG
CCCCATCGACCTACTACGACCACATCAACCGGGAGCCCAGCCGCCGCGAGCTGCGCGATGGCGAACTCAAGGAGCACATC
AGCCGCGTCCACGCCGCCAACTACGGTGTTTACGGTGCCCGCAAAGTGTGGCTAACCCTGAACCGTGAGGGCATCGAGGT
GGCCAGATGCACCGTCGAACGGCTGATGACCAAACTCGGCCTGTCCGGGACCACCCGCGGCAAAGCCCGCAGGACCACGA
TCGCTGATCCGGCCACAGCCCGTCCCGCCGATCTCGTCCAGCGCCGCTTCGGACCACCAGCACCTAACCGGCTGTGGGTA
GCAGACCTCACCTATGTGTCGACCTGGGCAGGGTTCGCCTACGTGGCCTTTGTCACCGACGCCTACGCTCGCAGGATCCT
GGGCTGGCGGGTCGCTTCCACGATGGCCACCTCCATGGTCCTCGACGCGATCGAGCAAGCCATCTGGACCCGCCAACAAG
AAGGCGTACTCGACCTGAAAGACGTTATCCACCATACGGATAGGGGATCTCAGTACACATCGATCCGGTTCAGCGAGCGG
CTCGCCGAGGCAGGCATCCAACCGTCGGTCGGAGCGGTCGGAAGCTCCTATGACAATGCACTAGCCGAGACGATCAACGG
CCTATACAAGACCGAGCTGATCAAACCCGGCAAGCCCTGGCGGTCCATCGAGGATGTCGAGTTGGCCACCGCGCGCTGGG
TCGACTGGTTCAACCATCGCCGCCTCTACCAGTACTGCGGCGACGTCCCGCCGGTCGAACTCGAGGCTGCCTACTACGCT
CAACGCCAGAGACCAGCCGCCGGCTGA

Protein sequence : 
KDRVGFLRGRARPASTLITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHI
SRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWV
ADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSER
LAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYA
QRQRPAAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAL67406.1 putative transposase Not tested PAI II CFT073 Protein 1e-57 55
ECO111_3721 YP_003236061.1 putative IS629 transposase OrfB Not tested LEE Protein 2e-62 53
ECO111_3776 YP_003236111.1 putative IS629 transposase OrfB Not tested LEE Protein 2e-62 53
ORF_34 AAZ04444.1 putative IS629 transposase Not tested PAI I APEC-O1 Protein 3e-61 52
ECO103_3585 YP_003223443.1 IS629 transposase OrfB Not tested LEE Protein 2e-60 52
APECO1_3499 YP_854312.1 transposase for IS629 Not tested PAI I APEC-O1 Protein 4e-61 52
IS629 CAI43840.1 transposase for IS629 Not tested LEE Protein 2e-59 52
IS629 CAC37926.1 transposase for IS629 Not tested LEE Protein 3e-60 52
IS629 CAI43821.1 transposase for IS629 Not tested LEE Protein 3e-60 52
IS629 CAI43909.1 transposase for IS629 1 Not tested LEE Protein 3e-60 52
c5178 NP_757026.1 transposase IS629 Not tested PAI II CFT073 Protein 5e-62 52
unnamed AAL67398.1 putative transposase Not tested PAI II CFT073 Protein 3e-62 52
unnamed CAD42083.1 hypothetical protein Not tested PAI II 536 Protein 1e-58 52
Z1660 NP_287162.1 transposase for IS629 Not tested TAI Protein 1e-61 51
Z1221 NP_286756.1 transposase Not tested TAI Protein 1e-61 51
Z1198 NP_286733.1 transposase Not tested TAI Protein 9e-62 51
Z1638 NP_287141.1 transposase Not tested TAI Protein 9e-62 51
c5213 NP_757061.1 transposase IS629 Not tested PAI II CFT073 Protein 1e-61 51
tnp7109-25 YP_001800853.1 transposase for insertion sequence Not tested Not named Protein 8e-53 46
CDCE8392_1958 YP_005134489.1 transposase-like protein Not tested Not named Protein 6e-40 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Rv3475 NP_217992.2 Possible transposase for insertion element IS6110 [second part] VFG1602 Protein 7e-59 52