Gene Information

Name : purA (Rv0357c)
Accession : NP_214871.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Unknown
Product : Probable adenylosuccinate synthetase PurA (imp--aspartate ligase) (ADSS) (ampsase)
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : -
Position : 435471 - 436769 bp
Length : 1299 bp
Strand : -
Note : Rv0357c, (MTCY13E10.19c), len: 432 aa. Probable purA, adenylosuccinate synthase, equivalent to AL023514|MLCB4_13 from adenylosuccinate synthetase Mycobacterium leprae (432 aa), FASTA scores: opt: 2555,E(): 0, (87.9% identity in 431 aa overlap). Also highl

DNA sequence :
ATGCCGGCGATCGTCCTCATCGGCGCCCAATGGGGCGACGAGGGCAAGGGTAAGGCCACCGACCTGTTGGGTGGCCGCGT
GCAGTGGGTGGTGCGCTATCAGGGGGGCAACAACGCCGGGCACACCGTCGTCTTGCCTACCGGCGAGAATTTCGCATTGC
ATCTCATCCCGTCGGGTGTGCTGACGCCCGGGGTCACCAACGTTATCGGCAACGGCGTGGTGATCGATCCCGGTGTCCTG
CTCAATGAGCTGCGGGGACTGCAAGACCGCGGCGTGGACACCGCCAAGCTGTTGATCTCCGCCGACGCCCATCTGCTGAT
GCCTTACCACATTGCTATCGACAAGGTCACCGAGCGCTATATGGGCAGCAAGAAGATCGGCACCACCGGCCGTGGTATCG
GGCCGTGCTACCAGGACAAGATCGCCCGTATTGGGATCCGGGTCGCCGATGTGCTGGACCCGGAACAATTGACCCACAAG
GTCGAGGCCGCGTGCGAGTTCAAGAACCAAGTGCTGGTCAAGATCTACAACCGCAAGGCCCTGGACCCCGCGCAGGTGGT
CGACGCGCTGCTGGAGCAGGCCGAGGGTTTCAAGCATCGCATCGCCGACACCCGGCTGCTACTCAATGCTGCCCTGGAGG
CCGGCGAAACGGTGCTGCTGGAAGGCTCTCAAGGCACCCTGCTCGATGTCGACCACGGCACCTACCCGTATGTGACATCG
TCGAATCCGACGGCGGGTGGCGCGGCCGTGGGCTCTGGTATCGGCCCGACCCGCATCGGCACCGTGCTGGGGATTCTCAA
GGCCTACACCACTCGGGTGGGCTCCGGCCCGTTCCCCACCGAGCTGTTCGACGAACACGGCGAATACCTGTCCAAGACTG
GCCGCGAGTTCGGTGTGACCACCGGCCGGCGCCGGCGCTGCGGCTGGTTCGACGCCGTCATTGCCCGCTACGCCGCCCGG
GTCAACGGCATCACCGACTACTTCCTGACCAAGCTCGACGTGCTGTCCAGCCTGGAATCGGTGCCGGTCTGCGTCGGATA
TGAGATCGACGGCCGGCGCACCCGCGATATGCCGATGACCCAGCGGGATCTTTGCCGCGCCAAGCCGGTTTACGAGGAGC
TGCCGGGCTGGTGGGAAGACATCTCCGGGGCGCGCGAGTTCGACGACCTGCCCGCCAAAGCGCGTGATTATGTGCTGCGA
CTGGAACAGCTTGCCGGAGCACCGGTTTCGTGCATTGGAGTCGGTCCGGGGCGGGAACAGACCATCGTGCGCCGGGACGT
CCTGCAGGATCGCCCGTGA

Protein sequence :
MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGENFALHLIPSGVLTPGVTNVIGNGVVIDPGVL
LNELRGLQDRGVDTAKLLISADAHLLMPYHIAIDKVTERYMGSKKIGTTGRGIGPCYQDKIARIGIRVADVLDPEQLTHK
VEAACEFKNQVLVKIYNRKALDPAQVVDALLEQAEGFKHRIADTRLLLNAALEAGETVLLEGSQGTLLDVDHGTYPYVTS
SNPTAGGAAVGSGIGPTRIGTVLGILKAYTTRVGSGPFPTELFDEHGEYLSKTGREFGVTTGRRRRCGWFDAVIARYAAR
VNGITDYFLTKLDVLSSLESVPVCVGYEIDGRRTRDMPMTQRDLCRAKPVYEELPGWWEDISGAREFDDLPAKARDYVLR
LEQLAGAPVSCIGVGPGREQTIVRRDVLQDRP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 1e-102 52