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Name : guaA (Rv3396c) Accession : NP_217913.1 Strain : Mycobacterium tuberculosis H37Rv Genome accession: NC_000962 Putative virulence/resistance : Unknown Product : Probable GMP synthase [glutamine-hydrolyzing] GuaA (glutamine amidotransferase) (GMP synthetase) Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : - Position : 3812501 - 3814078 bp Length : 1578 bp Strand : - Note : Rv3396c, (MTCY78.32), len: 525 aa. Probable guaA,gmp synthase (see citation below), equivalent to P46810|GUAA_MYCLE|ML0395|B1620_C2_205 GMP synthase [glutamine-hydrolyzing] from Mycobacterium leprae (529 aa),FASTA scores: opt: 2992, E(): 8.5e-168, (86.85% DNA sequence : GTGGTGCAGCCTGCTGACATCGACGTGCCTGAGACACCGGCTCGACCGGTGTTGGTGGTCGACTTCGGTGCCCAATATGC CCAGTTGATTGCCCGTCGGGTTCGAGAAGCACGGGTTTTCTCCGAGGTGATTCCGCACACCGCCTCGATCGAGGAGATCA GGGCCCGTCAGCCGGTGGCGCTCGTGCTTTCCGGTGGACCGGCCAGTGTCTACGCCGACGGCGCTCCGAAACTCGATCCG GCGCTACTGGACCTCGGTGTACCGGTTCTTGGCATCTGCTACGGGTTTCAGGCCATGGCGCAGGCGCTCGGGGGGATCGT CGCCCACACCGGCACTCGCGAATACGGTCGGACTGAACTGAAAGTCCTTGGTGGCAAACTGCATTCGGATCTTCCCGAGG TTCAGCCGGTATGGATGAGTCACGGTGACGCGGTCACGGCCGCGCCGGACGGATTCGACGTGGTGGCTAGCAGCGCCGGT GCCCCGGTGGCCGCCTTCGAGGCCTTCGACCGGCGCCTGGCCGGGGTGCAGTATCACCCGGAGGTGATGCACACCCCACA CGGGCAACAGGTGCTCAGCCGGTTTTTGCACGACTTCGCCGGGCTCGGCGCCCAGTGGACGCCCGCCAACATCGCCAACG CGCTGATCGAGCAGGTGCGCACCCAGATCGGCGACGGCCACGCCATCTGCGGGCTATCCGGCGGCGTGGATTCCGCGGTG GCCGCGGCCCTGGTGCAGCGGGCCATCGGCGACCGGTTGACCTGTGTCTTCGTCGACCACGGGCTGTTGCGCGCCGGTGA GCGGGCGCAGGTGCAACGCGATTTCGTGGCCGCCACCGGCGCCAACCTGGTCACCGTCGACGCGGCCGAGACCTTCCTCG AGGCGCTGTCGGGCGTGAGCGCCCCCGAGGGCAAACGCAAGATCATCGGCCGTCAGTTCATCCGCGCGTTCGAGGGCGCG GTGCGGGATGTGCTGGACGGTAAGACTGCTGAGTTCCTGGTGCAGGGCACGCTGTATCCGGATGTGGTGGAGTCCGGCGG GGGCAGCGGCACCGCGAACATCAAGAGCCACCACAATGTCGGCGGCCTGCCCGACGACCTGAAGTTCACCCTCGTTGAGC CGCTGCGGCTGCTGTTCAAAGACGAGGTGCGCGCGGTCGGGCGGGAGTTGGGTCTGCCGGAGGAGATCGTGGCGCGCCAG CCGTTTCCGGGACCGGGGTTGGGTATTCGGATCGTCGGGGAGGTCACCGCCAAGCGGTTGGATACGCTGCGGCACGCCGA TTCGATCGTGCGTGAGGAGCTGACCGCGGCGGGCCTGGACAACCAGATCTGGCAGTGTCCGGTGGTGCTGTTGGCCGATG TCCGCTCGGTGGGTGTGCAGGGTGACGGTCGCACCTATGGCCACCCGATTGTGCTGCGTCCGGTGTCGAGTGAAGACGCG ATGACCGCCGACTGGACCCGGGTGCCCTACGAGGTGCTCGAGCGCATCTCGACCCGGATCACCAACGAGGTCGCCGAGGT CAACCGCGTGGTGCTGGACATCACCAGCAAGCCGCCCGCCACCATCGAGTGGGAGTAG Protein sequence : MVQPADIDVPETPARPVLVVDFGAQYAQLIARRVREARVFSEVIPHTASIEEIRARQPVALVLSGGPASVYADGAPKLDP ALLDLGVPVLGICYGFQAMAQALGGIVAHTGTREYGRTELKVLGGKLHSDLPEVQPVWMSHGDAVTAAPDGFDVVASSAG APVAAFEAFDRRLAGVQYHPEVMHTPHGQQVLSRFLHDFAGLGAQWTPANIANALIEQVRTQIGDGHAICGLSGGVDSAV AAALVQRAIGDRLTCVFVDHGLLRAGERAQVQRDFVAATGANLVTVDAAETFLEALSGVSAPEGKRKIIGRQFIRAFEGA VRDVLDGKTAEFLVQGTLYPDVVESGGGSGTANIKSHHNVGGLPDDLKFTLVEPLRLLFKDEVRAVGRELGLPEEIVARQ PFPGPGLGIRIVGEVTAKRLDTLRHADSIVREELTAAGLDNQIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDA MTADWTRVPYEVLERISTRITNEVAEVNRVVLDITSKPPATIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 0.0 | 78 |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 1e-130 | 51 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 1e-130 | 51 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 9e-131 | 51 |
