Gene Information

Name : Rv3334 (Rv3334)
Accession : NP_217851.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Resistance
Product : Probable transcriptional regulatory protein (probably MerR-family)
Function : -
COG functional category : K : Transcription
COG ID : COG0789
EC number : -
Position : 3721257 - 3721697 bp
Length : 441 bp
Strand : +
Note : Rv3334, (MTV016.34), len: 146 aa. Probable transcriptional regulator, similar to many regulatory proteins (notably mercury resistance operon regulators) e.g. Q9HXV1|PA3689 probable transcriptional regulator MerR family from Pseudomonas aeruginosa (156 aa)

DNA sequence : 
ATGAAGATCAGCGAGGTAGCCGCGCTCACCAACACCAGCACCAAGACCCTCCGCTTCTACGAGAACTCGGGGCTGCTGCC
GCCGCCTGCACGCACAGCATCGGGGTATCGCAACTATGGACCCGAGATCGTGGATCGGCTGCGGTTTATCCATCGGGGCC
AAGCGGCCGGGCTGGCATTACAGGAAGTACGCCAAATCCTGGCCATCCACGACCGCGGCGAGGCGCCGTGCGCACACGTC
CGCCAACTACTGAGCACCCGCATCGACGAAGTCCGCGCGCAGATCGCCGAACTGATTGCCCTCGAAGGCCACTTGCAGAC
CCTGCTTGACCACGCTTCATATGGCCCGCCCACCGAACACGACCACTCCACGGTGTGTTGGATCCTGGAAAGCGACCTCG
ATGAGCCCACCGCCATCGAGGTCAGCGACATTCACGCCTAG

Protein sequence : 
MKISEVAALTNTSTKTLRFYENSGLLPPPARTASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIHDRGEAPCAHV
RQLLSTRIDEVRAQIAELIALEGHLQTLLDHASYGPPTEHDHSTVCWILESDLDEPTAIEVSDIHA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadR ACS32041.1 MerR family transcriptional regulator Not tested AbaR5 Protein 1e-19 42
ACICU_00234 YP_001844893.1 transcriptional regulator Not tested AbaR20 Protein 1e-19 42
cadR ADZ05769.1 MerR family transcriptional regulator Not tested AbaR11 Protein 1e-19 42
cadR ACN81029.1 MerR family transcriptional regulator Not tested AbaR5 Protein 1e-19 42
pbrR CAJ77021.1 transcription regulator Not tested AbaR1 Protein 1e-19 42
pbrR CAJ77094.1 Transcriptional regulator Not tested AbaR1 Protein 1e-19 42
cadR AGK36653.1 MerR family transcriptional regulator Not tested AbaR26 Protein 1e-19 42