Gene Information

Name : deoA (Rv3314c)
Accession : NP_217831.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Unknown
Product : Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase)
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0213
EC number : -
Position : 3702184 - 3703467 bp
Length : 1284 bp
Strand : -
Note : Rv3314c, (MTV016.14), len: 427 aa. Probable deoA,thymidine phosporylase, highly similar to many e.g. Q9AK36|DEOA from Streptomyces coelicolor (427 aa), FASTA scores: opt: 1668, E(): 3.2e-90, (62.35% identity in 425 aa overlap); Q9CFM5|PDP from Lactococcus

DNA sequence :
GTGACCGACTTCGCATTCGACGCCCCGACCGTCATCCGCACCAAACGTGACGGCGGCCGGTTGTCCGACGCCGCCATCGA
CTGGGTCGTCAAGGCCTATACCGACGGCCGGGTCGCCGACGAACAGATGTCGGCGCTGCTGATGGCGATCGTTTGGCGGG
GCATGGACCGCGGCGAGATCGCCAGATGGACGGCGGCCATGCTGGCCTCGGGTGCCCGGCTGGATTTCACCGATCTGCCA
CTAGCGACCGTGGACAAGCATTCCACCGGCGGGGTAGGTGACAAAATCACGCTGCCATTGGTGCCCGTCGTCGCCGCCTG
CGGTGGCGCAGTGCCCCAGGCGTCGGGCCGCGGACTCGGCCACACCGGCGGCACCCTGGACAAGCTGGAATCCATCACCG
GGTTCACCGCGAATCTGTCCAACCAGCGGGTGCGCGAGCAGCTTTGCGACGTCGGCGCCGCGATCTTCGCCGCCGGCCAG
CTGGCGCCAGCCGATGCCAAGCTGTATGCGCTGCGCGACATTACCGGCACCGTCGAATCGCTGCCGTTGATCGCCAGTTC
GATTATGAGCAAGAAGCTGGCTGAGGGTGCGGGTGCACTGGTGCTCGACGTCAAGGTTGGTTCCGGGGCCTTCATGAGGT
CGCCAGTGCAGGCGCGCGAACTTGCGCACACCATGGTCGAACTGGGCGCGGCGCATGGCGTGCCCACCCGTGCCCTGCTG
ACGGAGATGAACTGCCCGCTGGGTCGAACCGTCGGCAATGCGCTCGAGGTGGCCGAGGCGCTGGAGGTGCTGGCCGGCGG
CGGACCGCCCGACGTGGTGGAGCTGACGTTGCGGCTGGCCGGCGAGATGCTCGAGCTTGCCGGGATCCACGGCCGGGACC
CGGCCCAGACGCTGCGGGACGGCACCGCAATGGACCGGTTTCGCCGGTTGGTTGCCGCGCAGGGAGGTGACTTGTCGAAA
CCGTTGCCGATCGGTTCGCATTCGGAAACCGTCACGGCGGGCGCGAGCGGCACAATGGGCGACATCGATGCGATGGCAGT
GGGGTTAGCGGCATGGCGACTCGGTGCGGGCAGGTCCCGCCCGGGCGCACGCGTACAGCACGGTGCGGGGGTGCGGATTC
ATCGCCGCCCGGGGGAGCCGGTTGTGGTCGGTGAGCCGTTGTTCACCCTCTACACGAATGCTCCCGAGCGCTTTGGTGCG
GCGCGAGCCGAGCTGGCCGGCGGTTGGAGTATCCGGGACAGTCCGCCGCAGGTGCGGCCGCTAATCGTCGATCGGATCGT
CTGA

Protein sequence :
MTDFAFDAPTVIRTKRDGGRLSDAAIDWVVKAYTDGRVADEQMSALLMAIVWRGMDRGEIARWTAAMLASGARLDFTDLP
LATVDKHSTGGVGDKITLPLVPVVAACGGAVPQASGRGLGHTGGTLDKLESITGFTANLSNQRVREQLCDVGAAIFAAGQ
LAPADAKLYALRDITGTVESLPLIASSIMSKKLAEGAGALVLDVKVGSGAFMRSPVQARELAHTMVELGAAHGVPTRALL
TEMNCPLGRTVGNALEVAEALEVLAGGGPPDVVELTLRLAGEMLELAGIHGRDPAQTLRDGTAMDRFRRLVAAQGGDLSK
PLPIGSHSETVTAGASGTMGDIDAMAVGLAAWRLGAGRSRPGARVQHGAGVRIHRRPGEPVVVGEPLFTLYTNAPERFGA
ARAELAGGWSIRDSPPQVRPLIVDRIV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
deoA YP_005163381.1 Thymidine phosphorylase Not tested Not named Protein 7e-95 57