Gene Information

Name : aspC (Rv0337c)
Accession : NP_214851.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Unknown
Product : Probable aspartate aminotransferase AspC (transaminase A) (ASPAT)
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : -
Position : 401873 - 403162 bp
Length : 1290 bp
Strand : -
Note : Rv0337c, (MTCY279.04c), len: 429 aa. Probable aspC,aspartate aminotransferase (transaminase A), equivalent to CAC32019.1|AL583925 probable aspartate aminotransferase from Mycobacterium leprae (437 aa). Also highly similar to many e.g. Q48143|U32823 aspart

DNA sequence :
GTGGACAACGATGGCACCATTGTGGACGTGACAACCCACCAGCTGCCCTGGCACACCGCCAGCCATCAGCGGCAGCGCGC
CTTCGCTCAGTCGGCCAAGCTGCAGGACGTCCTGTACGAGATCCGCGGCCCGGTGCACCAGCACGCCGCGCGGCTCGAAG
CCGAAGGTCACCGCATCCTCAAACTCAACATCGGCAACCCGGCGCCGTTCGGCTTCGAAGCACCCGACGTGATCATGCGC
GATATCATCCAGGCGCTGCCCTACGCGCAGGGGTACTCCGACTCGCAGGGCATCCTGTCGGCCCGGCGTGCGGTGGTCAC
GCGCTACGAGCTGGTGCCCGGATTTCCCCGATTCGACGTGGACGACGTCTACCTGGGTAACGGGGTCTCCGAGCTGATCA
CGATGACGCTGCAAGCCCTGCTGGACAACGGCGATCAGGTGCTGATTCCATCACCGGACTACCCGCTGTGGACGGCGTCG
ACCTCGCTGGCTGGCGGCACTCCGGTCCACTACCTGTGCGATGAGACCCAAGGCTGGCAGCCCGATATCGCCGACCTGGA
ATCCAAGATCACCGAGCGCACCAAGGCGCTGGTCGTGATCAACCCCAACAACCCAACCGGCGCGGTGTACAGCTGCGAAA
TCCTCACCCAGATGGTCGATCTGGCCCGCAAGCATCAACTGCTGCTGTTGGCGGACGAAATCTACGACAAAATCCTCTAC
GACGACGCCAAGCACATCAGCCTGGCATCGATCGCCCCGGATATGTTGTGCCTGACCTTCAATGGGCTGTCGAAGGCCTA
CCGCGTCGCCGGATACCGGGCCGGCTGGCTGGCGATCACCGGACCCAAGGAGCACGCCAGCAGCTTCATCGAGGGCATCG
GCCTGCTGGCCAATATGCGGTTGTGCCCAAATGTCCCGGCCCAGCATGCCATTCAGGTTGCACTGGGCGGCCATCAGAGC
ATCGAGGACCTGGTGCTGCCCGGCGGCCGGCTGCTCGAGCAGCGCGACATCGCCTGGACCAAGCTCAACGAGATCCCGGG
GGTGTCGTGCGTCAAACCGGCGGGCGCGCTGTATGCGTTTCCCCGGCTAGACCCCGAGGTCTACGACATCGACGACGACG
AGCAACTCGTGCTCGATCTGCTGCTGTCGGAGAAGATCCTGGTCACCCAGGGCACCGGGTTCAACTGGCCCGCACCGGAT
CATCTGCGCCTGGTGACGCTGCCATGGTCCCGCGATCTGGCGGCCGCCATCGAGCGGCTGGGTAACTTCCTGGTCAGTTA
CCGGCAATAG

Protein sequence :
MDNDGTIVDVTTHQLPWHTASHQRQRAFAQSAKLQDVLYEIRGPVHQHAARLEAEGHRILKLNIGNPAPFGFEAPDVIMR
DIIQALPYAQGYSDSQGILSARRAVVTRYELVPGFPRFDVDDVYLGNGVSELITMTLQALLDNGDQVLIPSPDYPLWTAS
TSLAGGTPVHYLCDETQGWQPDIADLESKITERTKALVVINPNNPTGAVYSCEILTQMVDLARKHQLLLLADEIYDKILY
DDAKHISLASIAPDMLCLTFNGLSKAYRVAGYRAGWLAITGPKEHASSFIEGIGLLANMRLCPNVPAQHAIQVALGGHQS
IEDLVLPGGRLLEQRDIAWTKLNEIPGVSCVKPAGALYAFPRLDPEVYDIDDDEQLVLDLLLSEKILVTQGTGFNWPAPD
HLRLVTLPWSRDLAAAIERLGNFLVSYRQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 3e-144 72
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 3e-144 72
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 3e-144 72
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 3e-144 72