Gene Information

Name : Rv3083 (Rv3083)
Accession : NP_217599.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Unknown
Product : Probable monooxygenase (hydroxylase)
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2072
EC number : -
Position : 3448504 - 3449991 bp
Length : 1488 bp
Strand : +
Note : Rv3083, (MTV013.04), len: 495 aa. Probable monooxygenase, highly similar to other putative monooxygenases flavin-binding family e.g. AAK48336|MT3969 from Mycobacterium tuberculosis strain CDC1551 (489 aa),FASTA scores: opt: 1692, E(): 4.9e-98, (49.7% iden

DNA sequence :
ATGAACCAGCATTTCGACGTCCTGATCATCGGCGCCGGCCTATCCGGCATCGGGACGGCCTGTCACGTGACGGCCGAGTT
CCCCGACAAGACAATCGCCCTCCTGGAACGACGGGAGCGCCTGGGCGGCACCTGGGACTTGTTCCGCTACCCGGGAGTTC
GTTCGGACTCCGACATGTTCACCTTCGGCTACAAGTTCCGCCCGTGGCGCGACGTGAAGGTGCTCGCCGACGGCGCGTCG
ATCCGGCAGTACATCGCCGACACCGCCACGGAGTTCGGCGTCGACGAGAAGATTCACTACGGCCTGAAGGTCAACACCGC
CGAGTGGTCGAGCCGGCAGTGCCGTTGGACCGTCGCGGGCGTGCACGAGGCGACCGGCGAAACCCGGACCTACACCTGCG
ATTACCTCATCAGCTGCACCGGCTACTACAACTACGACGCGGGTTATCTGCCGGACTTCCCCGGCGTGCACCGGTTCGGC
GGCCGGTGCGTGCACCCGCAGCACTGGCCCGAAGACCTCGATTATTCCGGCAAGAAGGTCGTCGTCATCGGCAGCGGCGC
AACGGCGGTCACTTTGGTTCCGGCGATGGCCGGCTCCAACCCCGGCAGTGCCGCGCACGTGACGATGCTGCAGCGATCCC
CGTCGTACATCTTCTCGCTGCCGGCGGTCGACAAGATCTCCGAAGTCCTGGGCCGCTTCCTGCCGGATCGCTGGGTCTAC
GAGTTTGGCCGCAGGCGCAACATCGCCATCCAGCGAAAGCTCTACCAGGCCTGCCGGCGCTGGCCCAAGCTGATGCGGCG
ATTGCTGCTGTGGGAGGTACGACGCCGCCTCGGCCGCTCCGTGGACATGAGCAACTTCACCCCGAACTACCTGCCGTGGG
ACGAGCGGTTGTGCGCCGTGCCCAACGGCGATCTGTTTAAGACGCTGGCCTCGGGCGCGGCGTCGGTGGTGACCGATCAG
ATCGAGACCTTCACCGAGAAGGGCATCCTGTGCAAGTCCGGCCGGGAGATCGAGGCCGACATCATCGTCACCGCGACCGG
TCTGAACATCCAGATGCTGGGCGGGATGCGACTCATCGTGGACGGCGCCGAATACCAGCTGCCGGAGAAGATGACCTATA
AGGGTGTGCTGCTGGAAAACGCCCCCAATCTGGCCTGGATCATCGGCTACACCAACGCGTCATGGACCCTGAAGTCCGAC
ATCGCCGGCGCCTACCTGTGCCGGCTGCTGCGGCACATGGCCGACAACGGCTACACGGTGGCAACGCCGCGCGATGCGCA
GGACTGCGCGCTGGACGTTGGCATGTTCGACCAGCTGAACTCCGGCTATGTGAAGCGCGGCCAGGACATCATGCCGCGCC
AGGGCTCCAAGCATCCGTGGAGGGTGCTCATGCACTACGAGAAGGACGCCAAGATCCTGCTCGAAGACCCCATCGATGAC
GGCGTGCTGCACTTCGCCGCAGCGGCCCAAGACCACGCGGCGGCCTGA

Protein sequence :
MNQHFDVLIIGAGLSGIGTACHVTAEFPDKTIALLERRERLGGTWDLFRYPGVRSDSDMFTFGYKFRPWRDVKVLADGAS
IRQYIADTATEFGVDEKIHYGLKVNTAEWSSRQCRWTVAGVHEATGETRTYTCDYLISCTGYYNYDAGYLPDFPGVHRFG
GRCVHPQHWPEDLDYSGKKVVVIGSGATAVTLVPAMAGSNPGSAAHVTMLQRSPSYIFSLPAVDKISEVLGRFLPDRWVY
EFGRRRNIAIQRKLYQACRRWPKLMRRLLLWEVRRRLGRSVDMSNFTPNYLPWDERLCAVPNGDLFKTLASGAASVVTDQ
IETFTEKGILCKSGREIEADIIVTATGLNIQMLGGMRLIVDGAEYQLPEKMTYKGVLLENAPNLAWIIGYTNASWTLKSD
IAGAYLCRLLRHMADNGYTVATPRDAQDCALDVGMFDQLNSGYVKRGQDIMPRQGSKHPWRVLMHYEKDAKILLEDPIDD
GVLHFAAAAQDHAAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAK01510.1 aromatic-ring hyroxylase Not tested PAGI-1 Protein 4e-103 49