Gene Information

Name : drrA (Rv2936)
Accession : NP_217452.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Unknown
Product : Daunorubicin-dim-transport ATP-binding protein ABC transporter DrrA
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1131
EC number : -
Position : 3272214 - 3273209 bp
Length : 996 bp
Strand : +
Note : Rv2936, (MTCY19H9.04), len: 331 aa. drrA,daunorubicin-dim-transport resistance ATP-binding protein ABC transporter, probably involved in daunorubicin resistance and phthiocerol dimycocerosate transport (see citations below), equivalent to Q49938|DRRA|ML23

DNA sequence :
ATGCGCAACGACGACATGGCGGTGGTGGTTAACGGGGTTCGCAAGACCTACGGCAAGGGCAAGATTGTGGCCCTCGATGA
CGTGAGTTTCAAGGTGCGCCGCGGTGAAGTGATCGGGCTGCTGGGCCCCAACGGGGCCGGCAAGACGACCATGGTGGACA
TCTTGTCGACGCTGACCCGACCGGATGCCGGCTCGGCGATCATCGCTGGCTACGATGTTGTTTCCGAACCGGCCGGTGTA
CGCCGCTCGATCATGGTCACCGGGCAGCAGGTGGCCGTCGACGACGCGCTTTCCGGTGAGCAGAACCTGGTGTTGTTTGG
TCGTCTGTGGGGACTGAGCAAGTCCGCGGCGCGCAAACGCGCCGCCGAACTGCTCGAGCAATTCAGCCTCGTACATGCCG
GAAAGAGGCGGGTGGGCACCTACTCCGGCGGAATGCGCCGACGAATAGACATCGCGTGCGGATTGGTGGTCCAACCCCAG
GTGGCGTTCTTAGACGAGCCCACCACCGGGCTCGATCCCAGGAGCCGGCAAGCTATTTGGGATCTGGTGGCCAGCTTCAA
GAAGCTGGGCATTGCCACGTTGTTGACCACGCAGTATCTCGAGGAGGCGGATGCGCTCAGTGACCGCATCATCCTGATCG
ATCACGGCATAATCATCGCCGAAGGCACCGCGAATGAACTCAAGCACCGCGCCGGCGACACCTTCTGCGAAATAGTGCCC
CGCGATCTGAAGGATCTGGACGCTATCGTCGCGGCGCTCGGTTCGCTGTTGCCCGAGCACCACAGGGCGATGCTGACGCC
CGACTCAGACCGCATTACGATGCCGGCGCCTGACGGCATACGTATGCTCGTCGAGGCAGCGCGCCGGATCGACGAGGCGA
GGATCGAGCTAGCCGATATTGCGCTGCGCCGACCGTCACTCGATCACGTATTCCTGGCCATGACGACCGATCCCACCGAG
TCTCTGACCCATCTGGTGTCGGGGTCCGCGCGATGA

Protein sequence :
MRNDDMAVVVNGVRKTYGKGKIVALDDVSFKVRRGEVIGLLGPNGAGKTTMVDILSTLTRPDAGSAIIAGYDVVSEPAGV
RRSIMVTGQQVAVDDALSGEQNLVLFGRLWGLSKSAARKRAAELLEQFSLVHAGKRRVGTYSGGMRRRIDIACGLVVQPQ
VAFLDEPTTGLDPRSRQAIWDLVASFKKLGIATLLTTQYLEEADALSDRIILIDHGIIIAEGTANELKHRAGDTFCEIVP
RDLKDLDAIVAALGSLLPEHHRAMLTPDSDRITMPAPDGIRMLVEAARRIDEARIELADIALRRPSLDHVFLAMTTDPTE
SLTHLVSGSAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
CDC7B_2054 YP_005163495.1 methionine import ATP-binding protein Not tested Not named Protein 3e-54 46
CDCE8392_1976 YP_005134507.1 methionine import ATP-binding protein Not tested Not named Protein 3e-54 46