Gene Information

Name : aldC (Rv2858c)
Accession : NP_217374.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Unknown
Product : Probable aldehyde dehydrogenase AldC
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 3169356 - 3170723 bp
Length : 1368 bp
Strand : -
Note : Rv2858c, (MTV003.04c), len: 455 aa. Probable aldC,aldehyde dehydrogenase, similar to many e.g. O88069|SCI35.34c putative aldehyde dehydrogenase from Streptomyces coelicolor (483 aa), FASTA scores: opt: 1872,E(): 6.4e-109, (64.5% identity in 448 aa overlap

DNA sequence :
ATGAGTACCACGCAACTGATCAATCCCGCCACCGAGGAAGTGCTGGCCTCAGTTGACCACACCGACGCCAACGCGGTGGA
CGACGCCGTGCAACGCGCGCGAGCAGCGCAGCGGCGCTGGGCACGGTTGGCACCGGCGCAGCGGGCGGCCGGCCTGCGCG
CATTCGCGGCAGCCGTGCAAGCCCACCTCGACGAACTGGCCGCGCTCGAGGTAGCCAATTCCGGACATCCGATCGTGTCG
GCCGAGTGGGAAGCCGGCCACGTGCGTGACGTGTTGGCGTTCTATGCCGCCAGCCCGGAACGGTTGTCCGGCAGGCAGAT
TCCCGTTGCCGGCGGGGTGGACGTCACTTTCAACGAACCGATGGGCGTGGTCGGTGTGATCACGCCATGGAATTTCCCGA
TGGTGATCGCGTCCTGGGCCATCGCGCCGGCGCTGGCCGCCGGCAACGCGGTGCTGGTCAAACCCGCCGAACTGACGCCG
CTGACCACGATGCGGCTCGGTGAGCTGGCCGTCGAGGCGGGTCTGGACGAAGACCTGCTGCAGGTGTTGCCGGGAAAGGG
CACGGTGGTCGGGGAGCGGTTCGTCACCCACCCCGACATTCGCAAGATCGTGTTCACCGGGTCCACCGAAGTCGGCAAGC
GGGTCATGGCCGGTGCCGCGGCTCAAGTCAAACGAGTGACGTTGGAACTGGGTGGCAAGAGCGCCAACATCGTCTTCCAC
GACTGCGACCTGGAGCGCGCCGCGACGACCGCGCCGGCCGGGGTCTTCGACAACGCTGGGCAGGATTGCTGTGCCCGAAG
TCGAATCCTGGTGCAGCGCAGCGTTTACGACCGGTTTATGGAGCTGCTCGAGCCGGCGGTACACAGCATTGTCGTCGGGG
ACCCCGGATCACGCGCCACCGAGATGGGTCCGCTGGTATCGCGCGCACACCGTGACAAGGTCGCCGGTTATGTGCCCGAC
GACGCTCCGGTGGCGTTTCGGGGTACGGCTCCGGCTGGGCGCGGATTTTGGTTTCCACCAACCGTTCTCACACCCAAACG
CGGCGACCGCACCGTCACCGACGAAATCTTCGGGCCGGTGGTTGTAGTGCTGACGTTCGACGACGAGGCCGACGCTATCA
GCCTGGCCAACGACACCGCGTACGGGCTGTCCGGATCGATCTGGACCGATGACCTGTCCCGCGCGCTGCGGGTGGCGCGG
GCGGTCGAATCCGGCAACCTGTCGGTAAACTCGCACTCGTCGGTGCGCTTCAACACCCCGTTTGGCGGTTTCAAGCAGTC
CGGTGTGGGCCGCGAGCTAGGGCCGGACGCTCCGCTGCAGTTCACCGAAACCAAAAATGTGTTCATCGCCGTCGGGGAGG
AGATGTGA

Protein sequence :
MSTTQLINPATEEVLASVDHTDANAVDDAVQRARAAQRRWARLAPAQRAAGLRAFAAAVQAHLDELAALEVANSGHPIVS
AEWEAGHVRDVLAFYAASPERLSGRQIPVAGGVDVTFNEPMGVVGVITPWNFPMVIASWAIAPALAAGNAVLVKPAELTP
LTTMRLGELAVEAGLDEDLLQVLPGKGTVVGERFVTHPDIRKIVFTGSTEVGKRVMAGAAAQVKRVTLELGGKSANIVFH
DCDLERAATTAPAGVFDNAGQDCCARSRILVQRSVYDRFMELLEPAVHSIVVGDPGSRATEMGPLVSRAHRDKVAGYVPD
DAPVAFRGTAPAGRGFWFPPTVLTPKRGDRTVTDEIFGPVVVVLTFDDEADAISLANDTAYGLSGSIWTDDLSRALRVAR
AVESGNLSVNSHSSVRFNTPFGGFKQSGVGRELGPDAPLQFTETKNVFIAVGEEM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAK01506.1 putative aldehyde dehydrogenase Not tested PAGI-1 Protein 2e-56 41
orf17 AAO17183.1 Orf17 Not tested tcd island Protein 7e-47 41