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Name : glnA1 (Rv2220) Accession : NP_216736.1 Strain : Mycobacterium tuberculosis H37Rv Genome accession: NC_000962 Putative virulence/resistance : Virulence Product : Glutamine synthetase GlnA1 (glutamine synthase) (GS-I) Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0174 EC number : - Position : 2487615 - 2489051 bp Length : 1437 bp Strand : + Note : Rv2220, (MTCY190.31, MTCY427.01), len: 478 aa. glnA1, glutamine synthetase class I (see Tullius et al.,2001), similar to many e.g. GLNA_STRCO|P15106 from Streptomyces coelicolor, FASTA score: (71.4% identity in 475 aa overlap); etc. Also similar to three DNA sequence : GTGACGGAAAAGACGCCCGACGACGTCTTCAAACTTGCCAAGGACGAGAAGGTCGAATATGTCGACGTCCGGTTCTGTGA CCTGCCTGGCATCATGCAGCACTTCACGATTCCGGCTTCGGCCTTTGACAAGAGCGTGTTTGACGACGGCTTGGCCTTTG ACGGCTCGTCGATTCGCGGGTTCCAGTCGATCCACGAATCCGACATGTTGCTTCTTCCCGATCCCGAGACGGCGCGCATC GACCCGTTCCGCGCGGCCAAGACGCTGAATATCAACTTCTTTGTGCACGACCCGTTCACCCTGGAGCCGTACTCCCGCGA CCCGCGCAACATCGCCCGCAAGGCCGAGAACTACCTGATCAGCACTGGCATCGCCGACACCGCATACTTCGGCGCCGAGG CCGAGTTCTACATTTTCGATTCGGTGAGCTTCGACTCGCGCGCCAACGGCTCCTTCTACGAGGTGGACGCCATCTCGGGG TGGTGGAACACCGGCGCGGCGACCGAGGCCGACGGCAGTCCCAACCGGGGCTACAAGGTCCGCCACAAGGGCGGGTATTT CCCAGTGGCCCCCAACGACCAATACGTCGACCTGCGCGACAAGATGCTGACCAACCTGATCAACTCCGGCTTCATCCTGG AGAAGGGCCACCACGAGGTGGGCAGCGGCGGACAGGCCGAGATCAACTACCAGTTCAATTCGCTGCTGCACGCCGCCGAC GACATGCAGTTGTACAAGTACATCATCAAGAACACCGCCTGGCAGAACGGCAAAACGGTCACGTTCATGCCCAAGCCGCT GTTCGGCGACAACGGGTCCGGCATGCACTGTCATCAGTCGCTGTGGAAGGACGGGGCCCCGCTGATGTACGACGAGACGG GTTATGCCGGTCTGTCGGACACGGCCCGTCATTACATCGGCGGCCTGTTACACCACGCGCCGTCGCTGCTGGCCTTCACC AACCCGACGGTGAACTCCTACAAGCGGCTGGTTCCCGGTTACGAGGCCCCGATCAACCTGGTCTATAGCCAGCGCAACCG GTCGGCATGCGTGCGCATCCCGATCACCGGCAGCAACCCGAAGGCCAAGCGGCTGGAGTTCCGAAGCCCCGACTCGTCGG GCAACCCGTATCTGGCGTTCTCGGCCATGCTGATGGCAGGCCTGGACGGTATCAAGAACAAGATCGAGCCGCAGGCGCCC GTCGACAAGGATCTCTACGAGCTGCCGCCGGAAGAGGCCGCGAGTATCCCGCAGACTCCGACCCAGCTGTCAGATGTGAT CGACCGTCTCGAGGCCGACCACGAATACCTCACCGAAGGAGGGGTGTTCACAAACGACCTGATCGAGACGTGGATCAGTT TCAAGCGCGAAAACGAGATCGAGCCGGTCAACATCCGGCCGCATCCCTACGAATTCGCGCTGTACTACGACGTTTAA Protein sequence : MTEKTPDDVFKLAKDEKVEYVDVRFCDLPGIMQHFTIPASAFDKSVFDDGLAFDGSSIRGFQSIHESDMLLLPDPETARI DPFRAAKTLNINFFVHDPFTLEPYSRDPRNIARKAENYLISTGIADTAYFGAEAEFYIFDSVSFDSRANGSFYEVDAISG WWNTGAATEADGSPNRGYKVRHKGGYFPVAPNDQYVDLRDKMLTNLINSGFILEKGHHEVGSGGQAEINYQFNSLLHAAD DMQLYKYIIKNTAWQNGKTVTFMPKPLFGDNGSGMHCHQSLWKDGAPLMYDETGYAGLSDTARHYIGGLLHHAPSLLAFT NPTVNSYKRLVPGYEAPINLVYSQRNRSACVRIPITGSNPKAKRLEFRSPDSSGNPYLAFSAMLMAGLDGIKNKIEPQAP VDKDLYELPPEEAASIPQTPTQLSDVIDRLEADHEYLTEGGVFTNDLIETWISFKRENEIEPVNIRPHPYEFALYYDV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| glnA | YP_003728749.1 | glutamine synthetase | Not tested | cag PAI | Protein | 8e-89 | 45 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| glnA1 | NP_216736.1 | Glutamine synthetase GlnA1 (glutamine synthase) (GS-I) | VFG1399 | Protein | 0.0 | 100 |
