Gene Information

Name : tpx (Rv1932)
Accession : NP_216448.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Virulence
Product : Probable thiol peroxidase Tpx
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 2183372 - 2183869 bp
Length : 498 bp
Strand : +
Note : Rv1932, (MTCY09F9.32c), len: 165 aa. Probable tpx (alternate gene name: cfp20), thiol peroxidase similar to TPX_ECOLI|P37901 thiol peroxidase (p20) from Escherichia coli (167 aa), fasta scores: opt: 535, E(): 7.3e-25, (52.4% identity in 164 aa overlap). T

DNA sequence : 
ATGGCACAGATAACCCTGCGAGGAAACGCGATCAATACCGTCGGTGAGCTACCTGCTGTCGGATCCCCGGCCCCGGCCTT
CACCCTGACCGGGGGCGATCTGGGGGTGATCAGCAGCGACCAGTTCCGGGGTAAGTCCGTGTTGCTGAACATCTTTCCAT
CCGTGGACACACCGGTGTGCGCGACGAGTGTGCGAACCTTCGACGAGCGTGCGGCGGCAAGTGGCGCTACCGTGCTGTGT
GTCTCGAAGGATCTGCCGTTCGCCCAGAAGCGCTTCTGCGGCGCCGAGGGCACCGAAAACGTCATGCCCGCGTCGGCATT
CCGGGACAGCTTCGGCGAGGATTACGGCGTGACCATCGCCGACGGGCCGATGGCCGGGCTGCTCGCCCGCGCAATCGTGG
TGATCGGCGCGGACGGCAACGTCGCCTACACGGAATTGGTGCCGGAAATCGCGCAAGAACCCAACTACGAAGCGGCGCTG
GCCGCGCTGGGCGCCTAG

Protein sequence : 
MAQITLRGNAINTVGELPAVGSPAPAFTLTGGDLGVISSDQFRGKSVLLNIFPSVDTPVCATSVRTFDERAAASGATVLC
VSKDLPFAQKRFCGAEGTENVMPASAFRDSFGEDYGVTIADGPMAGLLARAIVVIGADGNVAYTELVPEIAQEPNYEAAL
AALGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 1e-33 44
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 2e-33 44
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 2e-33 43
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 1e-33 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx NP_216448.1 Probable thiol peroxidase Tpx VFG0087 Protein 4e-34 44