Gene Information

Name : ureG (Rv1852)
Accession : NP_216368.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Virulence
Product : Urease accessory protein UreG
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0378
EC number : -
Position : 2100340 - 2101014 bp
Length : 675 bp
Strand : +
Note : Rv1852, (MTCY359.21c), len: 224 aa. UreG, urease accessory protein. Identical to UREG_MYCTU|P50051 from M. tuberculosis. Contains PS00017 ATP/GTP-binding site motif A (P-loop). Belongs to the UreG family.

DNA sequence : 
ATGGCAACGCATTCCCATCCCCACTCGCACACCGTGCCCGCTCGGCCAAGGCGGGTCCGCAAACCGGGCGAGCCACTGCG
CATCGGCGTCGGCGGCCCGGTCGGCTCCGGCAAGACCGCACTGGTGGCGGCGCTGTGCCGGCAATTGCGGGGAGAGCTGT
CGCTGGCGGTGCTGACCAACGACATCTACACCACCGAAGACGCCGACTTCTTGCGCACACATGCGGTGCTGCCAGACGAC
CGGATCGCGGCCGTGCAGACCGGCGGCTGCCCGCACACCGCGATCCGCGACGACATCACCGCCAACCTGGATGCGATCGA
CGAGTTGATGGCCGCCCACGACGCGTTGGACCTGATCCTGGTCGAATCCGGCGGCGATAACCTCACGGCCACCTTCTCTT
CGGGGCTGGTGGATGCGCAGATCTTCGTCATTGACGTTGCCGGCGGCGACAAGGTGCCGCGCAAGGGCGGGCCGGGGGTG
ACCTATTCGGATTTGTTGGTAGTCAACAAGACTGACCTGGCTGCATTGGTGGGCGCCGACCTGGCGGTGATGGCCCGCGA
TGCGGACGCGGTGCGCGACGGCCGCCCGACGGTGCTGCAATCGTTGACCGAGGACCCAGCTGCCAGCGATGTCGTGGCCT
GGGTTCGTAGTCAACTGGCCGCCGATGGAGTCTAG

Protein sequence : 
MATHSHPHSHTVPARPRRVRKPGEPLRIGVGGPVGSGKTALVAALCRQLRGELSLAVLTNDIYTTEDADFLRTHAVLPDD
RIAAVQTGGCPHTAIRDDITANLDAIDELMAAHDALDLILVESGGDNLTATFSSGLVDAQIFVIDVAGGDKVPRKGGPGV
TYSDLLVVNKTDLAALVGADLAVMARDADAVRDGRPTVLQSLTEDPAASDVVAWVRSQLAADGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureG YP_005684263.1 urease accessory protein UreG Not tested PiCp 7 Protein 2e-41 56
ureG YP_003784322.1 urease accessory protein Not tested PiCp 7 Protein 2e-41 56
ureG YP_005686355.1 urease accessory protein UreG Not tested PiCp 7 Protein 2e-41 56
ureG YP_005682171.1 urease accessory protein UreG Not tested PiCp 7 Protein 2e-41 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureG NP_216368.1 Urease accessory protein UreG VFG0274 Protein 2e-43 55