Gene Information

Name : ureB (Rv1849)
Accession : NP_216365.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Virulence
Product : Urease beta subunit UreB (urea amidohydrolase)
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0832
EC number : -
Position : 2097647 - 2097961 bp
Length : 315 bp
Strand : +
Note : Rv1849, (MTCY359.24c), len: 104 aa. UreB, urease beta subunit. Identical to URE2_MYCTU|P50048 urease beta subunit from Mycobacterium tuberculosis (100 aa). Belongs to the urease gamma subunit family.

DNA sequence :
ATGATTCCCGGAGAAATCTTTTACGGCAGTGGTGATATCGAGATGAACGCCGCGGCACTCTCCCGCCTGCAGATGCGGAT
CATCAACGCCGGCGATCGTCCGGTGCAGGTCGGTAGCCACGTCCATCTCCCGCAGGCCAATCGGGCGCTGTCATTCGACC
GTGCGACGGCCCACGGCTACCGTCTGGACATCCCGGCGGCGACAGCGGTGCGCTTCGAGCCGGGCATTCCCCAAATCGTC
GGGTTGGTTCCGTTGGGCGGACGGCGCGAGGTACCCGGTCTGACGCTAAATCCGCCCGGACGGTTGGACCGCTGA

Protein sequence :
MIPGEIFYGSGDIEMNAAALSRLQMRIINAGDRPVQVGSHVHLPQANRALSFDRATAHGYRLDIPAATAVRFEPGIPQIV
GLVPLGGRREVPGLTLNPPGRLDR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureB NP_286679.1 urease subunit beta Virulence TAI Protein 1e-14 50
ureB NP_287087.1 urease subunit beta Not tested TAI Protein 1e-14 50
ureB YP_005682175.1 Urease beta subunit Not tested PiCp 7 Protein 2e-16 48
ureB YP_005684267.1 Urease beta subunit Not tested PiCp 7 Protein 2e-16 48
ureB YP_005686359.1 Urease beta subunit Not tested PiCp 7 Protein 2e-16 48
ureB YP_003784326.1 urease subunit beta Not tested PiCp 7 Protein 2e-16 48