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Name : guaB1 (Rv1843c) Accession : NP_216359.1 Strain : Mycobacterium tuberculosis H37Rv Genome accession: NC_000962 Putative virulence/resistance : Unknown Product : Probable inosine-5'-monophosphate dehydrogenase GuaB1(imp dehydrogenase) (IMPDH) (IMPD) Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0516 EC number : - Position : 2092259 - 2093698 bp Length : 1440 bp Strand : - Note : Rv1843c, (MTCY359.30), len: 479 aa. Probable guaB1,inosine-5'-monophosphate dehydrogenase. Similar to others e.g. IMDH_BACSU|P21879 from Bacillus subtilis (513 aa),FASTA score: opt: 904, E(): 0, (37.8% identity in 471 aa overlap). Similar to other Mycobac DNA sequence : GTGATGAGATTTCTAGACGGGCACCCACCCGGGTACGACCTGACATACAACGACGTGTTCATCGTTCCGAACCGATCCGA GGTCGCGTCGCGCTTCGACGTCGATTTGTCCACCGCCGACGGCTCGGGCACCACCATTCCGGTAGTGGTCGCCAATATGA CCGCGGTAGCCGGGCGGCGGATGGCCGAGACGGTCGCCCGCCGCGGTGGCATCGTAATCCTGCCGCAGGATCTGCCGATC CCGGCGGTAAAGCAGACGGTGGCGTTCGTCAAAAGCCGGGACCTGGTGCTCGACACCCCAGTGACGCTGGCACCCGACGA TTCGGTGTCCGACGCCATGGCGCTCATCCACAAGCGCGCACATGGCGTCGCGGTGGTCATCCTCGAGGGTCGCCCGATCG GATTGGTGCGCGAATCGTCCTGCCTGGGCGTGGATCGCTTCACCCGGGTGCGCGATATCGCCGTGACGGACTATGTGACC GCTCCAGCGGGAACCGAGCCACGCAAGATCTTCGACCTGCTGGAGCACGCCCCGGTCGACGTTGCGGTGCTGACCGACGC CGACGGCACGTTGGCGGGAGTGCTAAGCCGCACCGGGGCTATCCGCGCCGGTATCTACACCCCGGCCACCGATAGCGCGG GCCGGCTGCGGATCGGCGCGGCCGTCGGCATCAACGGCGACGTGGGCGCTAAGGCCCGAGCGCTCGCCGAAGCCGGCGTC GACGTGCTGGTCATCGACACCGCACACGGACACCAGGTCAAGACCTTGGACGCGATCAAGGCGGTCTCGGCACTGGACTT GGGTTTGCCGCTGGCGGCGGGAAACGTGGTGTCGGCGGAGGGCACCCGGGATCTGCTGAAAGCCGGGGCGAACGTCGTCA AGGTCGGTGTCGGCCCCGGCGCCATGTGCACCACCCGAATGATGACCGGTGTCGGCCGCCCGCAGTTCTCCGCTGTGCTC GAATGCGCTTCTGCGGCAAGGCAGCTCGGTGGTCATATCTGGGCCGACGGCGGGATCCGGCATCCACGCGACGTGGCTCT GGCGCTGGCCGCCGGCGCCTCGAACGTGATGATCGGATCGTGGTTCGCCGGCACCTACGAATCCCCCGGAGACCTGATGC GTGACCGCGACGATCAGCCGTACAAGGAGAGCTACGGCATGGCATCCAAGCGGGCGGTGGTGGCCCGGACCGGCGCGGAC AACCCGTTCGACCGAGCTCGTAAGGCGTTGTTCGAGGAAGGCATCTCGACGTCGCGGATGGGCCTTGACCCCGACCGCGG AGGTGTGGAGGACCTAATTGACCACATCACTTCTGGCGTGCGCAGCACCTGCACCTATGTGGGTGCCTCGAACCTGGCGG AGCTGCATGAGCGGGCCGTGGTGGGCGTGCAGTCGGGAGCGGGCTTTGCCGAGGGCCATCCGCTGCCCGCCGGCTGGTGA Protein sequence : MMRFLDGHPPGYDLTYNDVFIVPNRSEVASRFDVDLSTADGSGTTIPVVVANMTAVAGRRMAETVARRGGIVILPQDLPI PAVKQTVAFVKSRDLVLDTPVTLAPDDSVSDAMALIHKRAHGVAVVILEGRPIGLVRESSCLGVDRFTRVRDIAVTDYVT APAGTEPRKIFDLLEHAPVDVAVLTDADGTLAGVLSRTGAIRAGIYTPATDSAGRLRIGAAVGINGDVGAKARALAEAGV DVLVIDTAHGHQVKTLDAIKAVSALDLGLPLAAGNVVSAEGTRDLLKAGANVVKVGVGPGAMCTTRMMTGVGRPQFSAVL ECASAARQLGGHIWADGGIRHPRDVALALAAGASNVMIGSWFAGTYESPGDLMRDRDDQPYKESYGMASKRAVVARTGAD NPFDRARKALFEEGISTSRMGLDPDRGGVEDLIDHITSGVRSTCTYVGASNLAELHERAVVGVQSGAGFAEGHPLPAGW |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| CpC231_1472 | YP_005683835.1 | Inosine 5-monophosphate dehydrogenase | Not tested | PiCp 5 | Protein | 4e-132 | 58 |
| CpI19_1479 | YP_005685921.1 | Inosine 5-monophosphate dehydrogenase | Not tested | PiCp 5 | Protein | 4e-132 | 58 |
| cpfrc_01479 | YP_003783879.1 | hypothetical protein | Not tested | PiCp 5 | Protein | 3e-132 | 58 |
| Cp1002_1469 | YP_005681736.1 | Inosine 5-monophosphate dehydrogenase | Not tested | PiCp 5 | Protein | 1e-132 | 58 |
