Gene Information

Name : argH (Rv1659)
Accession : NP_216175.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Unknown
Product : Probable argininosuccinate lyase ArgH
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0165
EC number : -
Position : 1872639 - 1874051 bp
Length : 1413 bp
Strand : +
Note : Rv1659, (MTCY06H11.24), len: 470 aa. Probable argH,Argininosuccinate lyase, similar to ARLY_ECOLI|P11447 argininosuccinate lyase from Escherichia coli (457 aa),FASTA scores: opt: 1091, E(): 0, (42.5% identity in 461 aa overlap); contains PS00017 ATP/GTP-b

DNA sequence :
GTGAGCACCAACGAGGGGTCGCTGTGGGGCGGGCGGTTCGCCGGCGGCCCGTCCGACGCGCTGGCCGCGCTGAGCAAGTC
CACCCACTTCGACTGGGTGCTGGCCCCCTACGACCTCACCGCGTCGCGGGCGCACACCATGGTGCTGTTTCGGGCCGGGC
TGCTCACCGAGGAGCAACGCGACGGGCTGCTCGCCGGCCTGGACAGCCTCGCCCAAGACGTCGCCGACGGCAGCTTCGGC
CCGCTGGTCACCGACGAGGACGTGCATGCCGCGCTGGAGCGGGGCCTGATCGACCGGGTCGGACCGGACCTGGGCGGCCG
ACTGCGGGCCGGGCGCTCGCGCAACGACCAGGTGGCCGCGCTGTTTCGGATGTGGCTGCGCGACGCGGTGCGCCGGGTCG
CCACCGGTGTGCTCGACGTGGTCGGTGCGCTGGCAGAGCAGGCCGCCGCACACCCGAGCGCCATCATGCCCGGCAAAACC
CACCTGCAGTCCGCCCAGCCGATCCTGCTGGCACACCATCTGCTCGCGCACGCCCACCCCCTGCTGCGCGACCTGGACCG
CATCGTCGACTTCGACAAACGCGCGGCGGTGTCCCCGTACGGCTCGGGCGCCTTGGCCGGCTCGTCGCTGGGCCTGGATC
CCGACGCGATCGCCGCGGACCTCGGTTTCTCGGCTGCCGCGGACAACTCCGTCGACGCGACCGCCGCCCGCGACTTCGCC
GCCGAGGCGGCGTTCGTGTTCGCCATGATCGCCGTCGACCTGTCCCGGCTGGCTGAGGACATCATCGTCTGGAGCTCGAC
GGAATTCGGCTACGTCACGTTGCATGACTCGTGGTCCACCGGTAGCTCGATCATGCCGCAGAAGAAGAATCCGGACATCG
CCGAGCTGGCCCGCGGCAAGTCCGGGCGGCTGATCGGAAACCTGGCCGGGCTGCTGGCCACCCTGAAAGCCCAGCCCCTG
GCCTACAACCGCGACCTGCAGGAAGACAAGGAGCCGGTGTTCGATTCGGTGGCCCAGCTGGAGCTGCTGCTGCCGGCGAT
GGCCGGGCTGGTGGCCAGCCTGACCTTCAATGTCCAGCGGATGGCGGAGCTGGCCCCGGCCGGCTATACGTTGGCCACCG
ATCTCGCCGAATGGCTTGTGCGGCAAGGTGTTCCGTTTAGGTCCGCGCATGAGGCCGCGGGTGCGGCGGTGCGTGCGGCC
GAACAGCGCGGCGTGGGGCTGCAGGAACTCACCGACGACGAGCTGGCCGCCATCAGCCCCGAGCTGACCCCGCAAGTCCG
CGAGGTGCTGACCATCGAAGGCTCGGTGTCGGCCCGCGATTGCCGGGGTGGCACCGCGCCGGGCCGGGTTGCCGAGCAAC
TGAACGCCATTGGTGAAGCCGCCGAGCGGCTGCGCCGCCAGCTGGTGCGCTGA

Protein sequence :
MSTNEGSLWGGRFAGGPSDALAALSKSTHFDWVLAPYDLTASRAHTMVLFRAGLLTEEQRDGLLAGLDSLAQDVADGSFG
PLVTDEDVHAALERGLIDRVGPDLGGRLRAGRSRNDQVAALFRMWLRDAVRRVATGVLDVVGALAEQAAAHPSAIMPGKT
HLQSAQPILLAHHLLAHAHPLLRDLDRIVDFDKRAAVSPYGSGALAGSSLGLDPDAIAADLGFSAAADNSVDATAARDFA
AEAAFVFAMIAVDLSRLAEDIIVWSSTEFGYVTLHDSWSTGSSIMPQKKNPDIAELARGKSGRLIGNLAGLLATLKAQPL
AYNRDLQEDKEPVFDSVAQLELLLPAMAGLVASLTFNVQRMAELAPAGYTLATDLAEWLVRQGVPFRSAHEAAGAAVRAA
EQRGVGLQELTDDELAAISPELTPQVREVLTIEGSVSARDCRGGTAPGRVAEQLNAIGEAAERLRRQLVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00324 YP_008207789.1 Argininosuccinate lyase Not tested AbaR25 Protein 5e-60 44
BJAB0868_00328 YP_008211654.1 Argininosuccinate lyase Not tested AbaR26 Protein 5e-60 44