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Name : trpE (Rv1609) Accession : NP_216125.1 Strain : Mycobacterium tuberculosis H37Rv Genome accession: NC_000962 Putative virulence/resistance : Unknown Product : Anthranilate synthase component I TrpE (glutamine amidotransferase) Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0147 EC number : - Position : 1807903 - 1809453 bp Length : 1551 bp Strand : + Note : Rv1609, (MTCY01B2.01, MTV046.07), len: 516 aa. trpE,anthranilate synthase component I. FASTA best: TRPE_CLOTM|P14953 anthranilate synthase component I from Clostridium thermocellum (494 aa), E(): 0, (42.6% identity in 498 aa overlap). Some similarity to R DNA sequence : GTGCACGCCGACCTCGCAGCCACCACCTCGCGTGAGGATTTCCGCCTCCTGGCGGCCGAGCACCGGGTGGTTCCGGTGAC TCGCAAGGTCTTGGCCGACAGCGAGACGCCGCTGTCGGCCTACCGCAAGCTCGCCGCCAATCGCCCGGGTACGTTCCTGC TGGAGTCGGCCGAGAACGGCCGGTCGTGGTCGCGATGGTCGTTTATCGGTGCGGGGGCGCCAACGGCGTTGACCGTGCGT GAGGGGCAAGCGGTATGGCTGGGTGCCGTGCCCAAGGACGCTCCCACTGGCGGAGACCCGCTGCGGGCGCTGCAGGTGAC CTTGGAGCTGCTGGCTACGGCGGATCGTCAGTCCGAGCCGGGTCTTCCGCCGCTGTCGGGTGGCATGGTCGGTTTCTTCG CCTATGACATGGTGCGACGGCTGGAACGATTGCCGGAACGGGCCGTCGATGACCTCTGCCTGCCGGACATGCTGCTGTTG CTGGCCACCGATGTGGCGGCGGTCGATCACCACGAGGGCACCATCACGTTGATCGCCAACGCCGTGAACTGGAACGGCAC CGACGAGCGGGTCGACTGGGCCTACGACGACGCGGTCGCTCGGCTGGACGTGATGACCGCAGCGCTCGGCCAACCACTAC CGTCAACCGTGGCCACCTTCAGCCGACCCGAGCCGCGCCACCGTGCGCAACGCACCGTCGAAGAATATGGTGCGATCGTC GAATACTTGGTGGATCAGATTGCAGCCGGTGAAGCGTTCCAGGTGGTGCCCTCGCAGCGCTTCGAGATGGACACCGATGT CGATCCCATCGACGTGTACCGAATTCTGCGGGTAACCAACCCAAGTCCCTACATGTATCTACTGCAGGTGCCGAATAGTG ATGGTGCAGTGGACTTTTCGATTGTTGGATCCAGTCCGGAGGCGCTGGTAACGGTCCACGAAGGCTGGGCGACGACGCAT CCGATCGCCGGAACCCGGTGGCGCGGAAGGACAGACGACGAGGACGTGCTTCTGGAAAAAGAGCTGCTGGCGGACGACAA AGAACGTGCCGAGCATCTGATGCTGGTCGACCTCGGCCGAAACGACCTGGGTCGGGTCTGCACGCCGGGCACTGTTCGGG TCGAGGATTACAGCCACATCGAGCGGTACAGCCACGTGATGCACCTGGTGTCCACGGTGACCGGGAAGCTCGGCGAAGGG CGCACCGCGCTGGACGCGGTGACCGCCTGCTTTCCGGCCGGCACGCTGTCGGGCGCGCCGAAGGTGCGGGCGATGGAGCT GATCGAAGAGGTGGAGAAGACACGCCGCGGCCTTTACGGCGGTGTCGTCGGTTACCTTGACTTCGCCGGCAACGCTGACT TCGCCATCGCCATCCGCACCGCGCTGATGCGTAACGGCACGGCTTATGTCCAGGCAGGCGGTGGTGTGGTGGCCGACTCC AACGGATCCTACGAATACAACGAGGCGAGGAACAAGGCTCGGGCTGTGCTCAACGCGATCGCTGCCGCCGAGACGCTGGC CGCTCCGGGCGCGAACCGCAGTGGCTGCTAA Protein sequence : MHADLAATTSREDFRLLAAEHRVVPVTRKVLADSETPLSAYRKLAANRPGTFLLESAENGRSWSRWSFIGAGAPTALTVR EGQAVWLGAVPKDAPTGGDPLRALQVTLELLATADRQSEPGLPPLSGGMVGFFAYDMVRRLERLPERAVDDLCLPDMLLL LATDVAAVDHHEGTITLIANAVNWNGTDERVDWAYDDAVARLDVMTAALGQPLPSTVATFSRPEPRHRAQRTVEEYGAIV EYLVDQIAAGEAFQVVPSQRFEMDTDVDPIDVYRILRVTNPSPYMYLLQVPNSDGAVDFSIVGSSPEALVTVHEGWATTH PIAGTRWRGRTDDEDVLLEKELLADDKERAEHLMLVDLGRNDLGRVCTPGTVRVEDYSHIERYSHVMHLVSTVTGKLGEG RTALDAVTACFPAGTLSGAPKVRAMELIEEVEKTRRGLYGGVVGYLDFAGNADFAIAIRTALMRNGTAYVQAGGGVVADS NGSYEYNEARNKARAVLNAIAAAETLAAPGANRSGC |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| BJAB07104_00338 | YP_008207803.1 | Anthranilate/para-aminobenzoate synthases component I | Not tested | AbaR25 | Protein | 2e-65 | 44 |
| BJAB0868_00342 | YP_008211668.1 | Anthranilate/para-aminobenzoate synthases component I | Not tested | AbaR26 | Protein | 2e-65 | 44 |
