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Name : tkt (Rv1449c) Accession : NP_215965.1 Strain : Mycobacterium tuberculosis H37Rv Genome accession: NC_000962 Putative virulence/resistance : Unknown Product : Transketolase Tkt (TK) Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : - Position : 1628097 - 1630199 bp Length : 2103 bp Strand : - Note : Rv1449c, (MTCY493.05), len: 700 aa. tkt,transketolase. Highly similar to several e.g. TKT_MYCLE|P46708 transketolase (tk) from Mycobacterium leprae (699 aa), FASTA scores: opt: 4216, E(): 0, (89.1% identity in 700 aa overlap). Start site chosen by homolog DNA sequence : GTGACCACACTCGAAGAGATCTCCGCGCTTACCCGACCGCGCCATCCCGACTACTGGACCGAGATCGATTCGGCTGCCGT CGACACCATCCGGGTATTGGCCGCCGATGCCGTCCAAAAGGTCGGCAACGGTCATCCTGGAACGGCGATGAGCCTGGCTC CGTTGGCCTACACGCTGTTTCAGCGGACAATGCGTCACGATCCCAGCGACACACACTGGCTGGGCCGCGATCGGTTCGTT TTGTCGGCCGGGCACAGCAGCCTGACCCTCTACATCCAGCTCTACCTCGGCGGCTTCGGCCTGGAACTGTCCGACATTGA GTCGTTGCGCACCTGGGGATCCAAGACCCCCGGACACCCGGAGTTCCGCCACACCCCCGGCGTTGAGATCACCACCGGCC CGCTGGGGCAGGGACTGGCGTCGGCGGTCGGGATGGCGATGGCCTCGCGCTACGAGCGCGGCCTGTTCGACCCGGACGCC GAACCGGGCGCCAGCCCCTTCGACCACTACATCTATGTCATCGCCTCCGACGGTGACATCGAAGAAGGGGTGACCTCGGA GGCGTCGTCGCTGGCCGCGGTCCAGCAACTGGGCAACCTCATCGTGTTCTACGACCGCAACCAGATCTCGATCGAGGACG ACACCAACATCGCGCTGTGTGAGGACACCGCGGCCCGCTACCGCGCGTACGGCTGGCACGTGCAAGAGGTTGAGGGCGGT GAGAACGTCGTCGGCATCGAGGAGGCCATCGCCAATGCGCAGGCGGTCACCGACCGGCCCTCGTTCATCGCGCTGCGCAC CGTCATCGGCTATCCGGCGCCGAACCTGATGGACACCGGCAAGGCGCACGGCGCGGCGCTGGGCGACGACGAGGTGGCCG CAGTCAAGAAGATCGTCGGCTTCGATCCGGACAAGACGTTCCAGGTCCGCGAGGACGTCCTCACCCACACCCGAGGGCTG GTGGCCCGCGGCAAACAGGCCCACGAACGCTGGCAGCTCGAATTCGATGCCTGGGCGCGGCGTGAACCCGAGCGCAAGGC GCTGCTGGACCGGCTGCTCGCGCAGAAGTTGCCCGACGGCTGGGACGCCGACTTGCCCCACTGGGAACCGGGGTCCAAGG CGCTGGCCACCCGTGCGGCCTCGGGTGCGGTGCTGTCCGCGCTCGGGCCGAAACTGCCCGAGTTGTGGGGCGGTTCGGCC GACCTGGCGGGCAGCAACAACACAACGATAAAGGGCGCCGACTCCTTTGGCCCGCCCTCGATTTCCACCAAGGAGTACAC CGCGCACTGGTATGGTCGCACCTTGCACTTCGGTGTTCGCGAGCACGCGATGGGTGCCATCCTGTCCGGCATCGTGCTGC ACGGACCCACCCGGGCTTACGGCGGCACCTTCCTGCAGTTCTCCGACTACATGCGCCCGGCGGTGCGGCTGGCGGCGTTG ATGGACATCGACACCATCTACGTCTGGACGCACGACTCGATCGGCCTCGGCGAAGACGGGCCCACCCATCAACCGATCGA GCACCTCTCGGCGCTGCGCGCGATCCCCCGGCTGTCGGTGGTGCGCCCGGCAGATGCCAACGAGACAGCCTACGCCTGGC GCACGATCCTGGCCCGCCGCAACGGCAGCGGGCCGGTCGGGTTGATCCTGACCCGCCAGGGTGTGCCGGTGCTGGACGGC ACCGACGCCGAGGGGGTTGCCCGCGGCGGTTACGTGCTGAGTGACGCCGGTGGTCTGCAACCGGGCGAGGAACCCGACGT CATTCTCATCGCCACCGGCTCGGAGGTGCAGCTGGCGGTCGCGGCGCAGACGTTGCTGGCGGACAACGACATCCTCGCTC GGGTGGTGTCGATGCCGTGCCTGGAGTGGTTCGAGGCCCAACCCTACGAGTACCGCGACGCGGTGCTGCCCCCGACGGTG TCGGCGCGGGTGGCCGTCGAAGCCGGCGTCGCGCAATGCTGGCACCAGCTGGTTGGCGACACGGGCGAGATCGTCTCGAT CGAGCACTACGGCGAATCCGCGGACCACAAGACCTTGTTCCGCGAGTACGGCTTCACTGCCGAGGCCGTGGCCGCCGCCG CCGAACGAGCGCTGGATAACTGA Protein sequence : MTTLEEISALTRPRHPDYWTEIDSAAVDTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRTMRHDPSDTHWLGRDRFV LSAGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTPGVEITTGPLGQGLASAVGMAMASRYERGLFDPDA EPGASPFDHYIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDRNQISIEDDTNIALCEDTAARYRAYGWHVQEVEGG ENVVGIEEAIANAQAVTDRPSFIALRTVIGYPAPNLMDTGKAHGAALGDDEVAAVKKIVGFDPDKTFQVREDVLTHTRGL VARGKQAHERWQLEFDAWARREPERKALLDRLLAQKLPDGWDADLPHWEPGSKALATRAASGAVLSALGPKLPELWGGSA DLAGSNNTTIKGADSFGPPSISTKEYTAHWYGRTLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLAAL MDIDTIYVWTHDSIGLGEDGPTHQPIEHLSALRAIPRLSVVRPADANETAYAWRTILARRNGSGPVGLILTRQGVPVLDG TDAEGVARGGYVLSDAGGLQPGEEPDVILIATGSEVQLAVAAQTLLADNDILARVVSMPCLEWFEAQPYEYRDAVLPPTV SARVAVEAGVAQCWHQLVGDTGEIVSIEHYGESADHKTLFREYGFTAEAVAAAAERALDN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 4e-113 | 44 |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 1e-112 | 42 |
