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Name : pncB1 (Rv1330c) Accession : NP_215846.2 Strain : Mycobacterium tuberculosis H37Rv Genome accession: NC_000962 Putative virulence/resistance : Unknown Product : Nicotinic acid phosphoribosyltransferase PncB1 Function : - COG functional category : H : Coenzyme transport and metabolism COG ID : COG1488 EC number : - Position : 1499213 - 1500559 bp Length : 1347 bp Strand : - Note : Rv1330c, (MTCY130.15c), len: 448 aa. PncB1,nicotinic acid phosphoribosyltransferase (See Boshoff et al., 2008). Similar to e.g. O32090 YUEK protein from Bacillus subtilis (490 aa), FASTA scores: E(): 8.6e-22,(37.9% identity in 369 aa overlap). Also simila DNA sequence : GTGGGGCCACCCCCAGCCGCCAGGCGGCGAGAGGGAGAGCCCGACAATCAAGACCCAGCCGGGCTGTTGACCGACAAGTA CGAGTTGACCATGCTGGCGGCTGCCCTGCGCGACGGCAGCGCCAATCGCCCCACCACATTCGAGGTGTTCGCTCGCCGAC TCCCCACCGGCCGTCGCTACGGAGTTGTCGCCGGAACCGGCCGGTTGCTGGAAGCGTTGCCGCAGTTCAGGTTCGACGCT GACGCGTGCGAGTTGCTGGCCCAATTCCTCGACCCGGCCACGGTGCGGTATCTTCGCGAATTCCGGTTCCGCGGCGATAT CGACGGCTATGCCGAGGGGGAGCTGTATTTTCCCGGGTCACCGGTGCTCTCGGTACGCGGCAGCTTCGCCGAATGCGTCC TGCTCGAAACGCTGGTGCTGTCAATCTTCAACCACGACACAGCGATCGCCTCGGCAGCGGCGCGCATGGTCAGCGCCGCC GGGGGGCGCCCACTGATCGAGATGGGCTCGCGGCGCACCCACGAACGCGCCGCGGTGGCAGCGGCCCGGGCGGCGTATAT CGCCGGTTTCGCCGCGTCATCCAACTTGGCGGCGCAGCGACGCTACGGAGTGCCCGCGCACGGCACCGCGGCACACGCAT TCACCATGTTGCACGCCCAGCATGGCGGCCCCACCGAACTAGCCGAGCGAGCCGCATTCCGCGCCCAGGTCGAAGCGCTG GGACCCGGTACCACGCTGCTGGTGGATACCTATGACGTCACGACCGGTGTGGCCAATGCCGTTGCCGCCGCCGGCGCTGA GCTCGGCGCGATCCGCATCGATTCCGGTGAGCTTGGGGTACTGGCCCGCCAAGCGCGGGAGCAGCTCGACCGGCTAGGAG CCACCCGGACGCGCATCGTGGTGTCCGGCGACCTTGACGAGTTCAGCATCGCCGCGTTGCGCGGTGAACCCGTCGACAGC TACGGCGTGGGCACGTCGCTGGTCACCGGGTCGGGCGCGCCGACCGCCAACATGGTCTACAAACTGGTCGAGGTAGACGG TGTACCGGTGCAAAAGCGCAGCAGCTACAAAGAATCCCCCGGCGGCCGCAAAGAGGCACTGCGGCGCTCCCGTGCGACGG GCACCATCACCGAGGAGCTCGTGCATCCGGCGGGCCGTCCGCCGGTCATTGTCGAGCCGCACCGGGTTTTGACGCTGCCA CTGGTCCGCGCCGGGCAACCGGTAGCCGATACCAGCCTGGCCGCGGCACGGCAGCTGGTGGCATCCGGGTTGCGCAGCCT GCCAGGCGACGGGCTGAAATTGGCACCCGGCGAGCCGGCGATTCCGACACGCACGATCCCGGCCTGA Protein sequence : MGPPPAARRREGEPDNQDPAGLLTDKYELTMLAAALRDGSANRPTTFEVFARRLPTGRRYGVVAGTGRLLEALPQFRFDA DACELLAQFLDPATVRYLREFRFRGDIDGYAEGELYFPGSPVLSVRGSFAECVLLETLVLSIFNHDTAIASAAARMVSAA GGRPLIEMGSRRTHERAAVAAARAAYIAGFAASSNLAAQRRYGVPAHGTAAHAFTMLHAQHGGPTELAERAAFRAQVEAL GPGTTLLVDTYDVTTGVANAVAAAGAELGAIRIDSGELGVLARQAREQLDRLGATRTRIVVSGDLDEFSIAALRGEPVDS YGVGTSLVTGSGAPTANMVYKLVEVDGVPVQKRSSYKESPGGRKEALRRSRATGTITEELVHPAGRPPVIVEPHRVLTLP LVRAGQPVADTSLAAARQLVASGLRSLPGDGLKLAPGEPAIPTRTIPA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| cur_1473 | YP_001800867.1 | nicotinate phosphoribosyltransferase | Not tested | Not named | Protein | 1e-95 | 62 |
