Gene Information

Name : thrC (Rv1295)
Accession : NP_215811.1
Strain : Mycobacterium tuberculosis H37Rv
Genome accession: NC_000962
Putative virulence/resistance : Unknown
Product : Threonine synthase ThrC (ts)
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0498
EC number : -
Position : 1450697 - 1451779 bp
Length : 1083 bp
Strand : +
Note : Rv1295, (MTCY373.15), len: 360 aa. thrC, threonine synthase (see Parish et al., 1999), highly similar to THRC_MYCLE|P45837 Mycobacterium leprae (360 aa), FASTA scores: opt: 2202, E(): 0, (93.9% identity in 359 aa overlap). Contains PS00165 Serine/threonin

DNA sequence :
ATGACCGTCCCGCCGACGGCCACTCACCAGCCGTGGCCGGGAGTGATTGCCGCGTACCGTGACCGGCTGCCGGTGGGTGA
CGACTGGACTCCGGTGACCCTGCTCGAGGGTGGTACTCCCCTCATCGCGGCAACTAATCTCTCCAAGCAGACGGGCTGCA
CGATCCACCTCAAAGTGGAGGGCCTCAACCCCACCGGCTCCTTCAAGGATCGTGGCATGACGATGGCGGTCACCGATGCC
CTTGCCCATGGTCAGCGGGCGGTCTTGTGCGCATCGACCGGAAATACCTCGGCGTCGGCGGCGGCCTATGCCGCCCGGGC
CGGCATCACCTGCGCGGTGCTGATACCGCAGGGCAAGATCGCGATGGGCAAGCTCGCACAGGCGGTCATGCACGGCGCCA
AGATCATCCAGATCGACGGTAACTTCGACGACTGCCTGGAACTGGCGCGCAAGATGGCCGCGGACTTCCCGACGATTTCG
TTGGTCAACTCGGTAAACCCGGTGCGCATCGAGGGCCAGAAAACGGCAGCGTTCGAGATCGTCGACGTGCTAGGTACCGC
GCCGGACGTGCATGCTCTGCCGGTTGGCAACGCCGGCAACATCACCGCGTACTGGAAGGGCTACACCGAGTATCACCAGC
TGGGCCTGATCGACAAGTTGCCCCGCATGCTGGGCACTCAGGCCGCGGGCGCGGCGCCCCTGGTGCTCGGCGAACCGGTG
AGCCACCCGGAGACCATCGCAACCGCGATCCGCATCGGCTCGCCGGCGTCGTGGACTTCGGCCGTCGAGGCACAGCAGCA
GTCCAAGGGCCGCTTCTTGGCCGCCTCCGACGAGGAGATACTGGCCGCATATCACCTGGTGGCTCGTGTCGAAGGCGTAT
TCGTGGAGCCCGCGTCCGCAGCCAGCATTGCGGGTCTCCTCAAAGCGATCGACGACGGCTGGGTGGCGCGTGGTTCGACG
GTGGTGTGCACGGTAACCGGCAACGGTCTTAAGGATCCCGACACCGCGCTCAAAGACATGCCGAGCGTGTCTCCGGTTCC
CGTGGACCCGGTAGCCGTCGTCGAGAAGCTAGGGCTGGCCTAG

Protein sequence :
MTVPPTATHQPWPGVIAAYRDRLPVGDDWTPVTLLEGGTPLIAATNLSKQTGCTIHLKVEGLNPTGSFKDRGMTMAVTDA
LAHGQRAVLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPTIS
LVNSVNPVRIEGQKTAAFEIVDVLGTAPDVHALPVGNAGNITAYWKGYTEYHQLGLIDKLPRMLGTQAAGAAPLVLGEPV
SHPETIATAIRIGSPASWTSAVEAQQQSKGRFLAASDEEILAAYHLVARVEGVFVEPASAASIAGLLKAIDDGWVARGST
VVCTVTGNGLKDPDTALKDMPSVSPVPVDPVAVVEKLGLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00304 YP_008207769.1 Threonine synthase Not tested AbaR25 Protein 2e-69 55
BJAB0868_00308 YP_008211634.1 Threonine synthase Not tested AbaR26 Protein 2e-69 55