Gene Information

Name : tktB_1 (CPn0893)
Accession : NP_225088.1
Strain : Chlamydophila pneumoniae CWL029
Genome accession: NC_000922
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1023894 - 1025891 bp
Length : 1998 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGATCAATAAAGAATTAGATATTGGTATTTTAGGAAAAATTGCTGGGGCTATTAAACAAATTAGTATTGAATCCATCCA
AAAGGCCTCTTCTGGTCATCCAGGACTTCCCCTAGGATGCGCAGAACTTGCTGCCTATTTATATGGTTATGTCCTGCGGC
AAAATCCACGTGATCCCCATTGGATTAATAGGGATCGGTTTGTCTTGTCAGCAGGTCATGGATCTGCTCTTCTCTATTCT
TGTTTGCATCTTGCCGGATTTGATGTTTCCTTAGAGGATCTTCAGGAATTTCGCCAGCTTCACTCCCGAACTCCCGGGCA
TCCCGAGTACGGCGAAACTGTGGGAGTCGAAGCAACGACAGGTCCTCTGGGACAGGGATTAGGCAATGCTGTCGGCATGG
CGCTCTCTATGAAGATGTTGGAATCCCGATTCAATCGCCCAGGACATGAGATTTTTAACGGAAAAATCTATTGTTTGGCA
GGGGATGGCTGTTTTATGGAGGGAGTCAGCCACGAAGTTTGTAGCTTTGCAGGCTCTTTAAATTTAAATAATCTTGTGGT
CATCTATGACTACAATAATGTTGTTCTCGATGGATATCTTAATGAAATTAGTGTTGAGGATACAAAAAAACGTTTTGAAG
CCTATGGCTGGGATGTATATGAAATTGATGGGTATGATTTTACCCATATTCATGAGACATTCTCGAGCATCAAACGGGGG
CAGGAACGTCCTGTATTAGTGATTGCACATACAATTATTGGTCATGGTTCGCCTAAGGAAGGGACAAATAAGGCTCATGG
TTCTCCTTTAGGAGTCGAAGGGACTCATGAAACAAAACAGTTTTGGCATCTCCCTGAAGAAAAGTTTTTTGTCCCTCCTG
CAGTAAAGAACTTCTTTGCTCATAAAATACAAGAAGATCGAAAAGCACAGGAGCAATGGCTGGATGAAGTTCGTGTTTGG
TCAAAACAGTTCCCAGAATTACACGAAGAATTCGTTGCGTTGACCTCTCATAAGTTACCTAAAAACTTAGAATCCTTGGT
GCAGAGTGTAGAAATGCCAGACTCTATAGCTGGCCGGGCTGCTTCAAATAAACTGATCCAAGTATTAGTACAGCACATTC
CTTATTTGATTGGAGGGTCCGCAGATCTTTCAAGCTCAGATGGAACTTGGATTGCGAATGAGAAAGTCATCCATACGTAT
GACTTCTCTGGAAGGAACATTAAATACGGCGTTCGTGAGTTTGGTATGGCCACAATCATGAATGGTTTAGCTTATAGCCA
GGTATTTCGTCCTTTTGGTGGAACATTTTTAGTTTTTTCTGACTATATGCGTAATGCAATTCGCTTGGCCGCATTATCTA
AATTACCAGTCATCTATCAATTTACCCATGATTCTATATTTGTTGGAGAAGATGGACCTACGCATCAGCCTGTGGAACAA
TTGATGTCTTTGCGCGCGATCCCTGGATTGTATGTAATACGTCCTGCCGATGCTAATGAAGTTAGAGGAGCGTGGATTGC
AGGATTAAAGCACACAGGTCCTACAGTCATTGTCTTGTCGCGACAAGCATTGCCCACACTGCCTGCTGCGCATCGGCCTT
TTAAAGATGGTATAGGTCGTGGTGCTTATATTGTCTTAAAAGAGTCAGGAGAAAAACCAGACTATACTCTCTTCGCTACA
GGGTCAGAAGTTTCTTTAGCTCTTTCTGTAGCTAAAGAACTCGAACACTTGGATAAGCAAGTGCGTGTAGTTTCTTTCCC
TTGTTGGGAGCTTTTTGAAGCTCAAGATGTGGACTACAAACAGAGTATTGTAGGCGGAGATCTTGGAATTCGTGTCTCTA
TAGAAGCAGGATCTGCTTTGGGGTGGTATAAGTATATCGGATCTGAAGGTTTAGCTATCGCTATGGATAGATTCGGATAC
TCAGGAGCTTCTGATGATGTATCAGAAGAATGTGGCTTTACTACAGAGCAAATCCTTCAGAGGATTCTCTCTCAATAG

Protein sequence :
MINKELDIGILGKIAGAIKQISIESIQKASSGHPGLPLGCAELAAYLYGYVLRQNPRDPHWINRDRFVLSAGHGSALLYS
CLHLAGFDVSLEDLQEFRQLHSRTPGHPEYGETVGVEATTGPLGQGLGNAVGMALSMKMLESRFNRPGHEIFNGKIYCLA
GDGCFMEGVSHEVCSFAGSLNLNNLVVIYDYNNVVLDGYLNEISVEDTKKRFEAYGWDVYEIDGYDFTHIHETFSSIKRG
QERPVLVIAHTIIGHGSPKEGTNKAHGSPLGVEGTHETKQFWHLPEEKFFVPPAVKNFFAHKIQEDRKAQEQWLDEVRVW
SKQFPELHEEFVALTSHKLPKNLESLVQSVEMPDSIAGRAASNKLIQVLVQHIPYLIGGSADLSSSDGTWIANEKVIHTY
DFSGRNIKYGVREFGMATIMNGLAYSQVFRPFGGTFLVFSDYMRNAIRLAALSKLPVIYQFTHDSIFVGEDGPTHQPVEQ
LMSLRAIPGLYVIRPADANEVRGAWIAGLKHTGPTVIVLSRQALPTLPAAHRPFKDGIGRGAYIVLKESGEKPDYTLFAT
GSEVSLALSVAKELEHLDKQVRVVSFPCWELFEAQDVDYKQSIVGGDLGIRVSIEAGSALGWYKYIGSEGLAIAMDRFGY
SGASDDVSEECGFTTEQILQRILSQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-127 45
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 7e-117 44