Gene Information

Name : serS (CPn0870)
Accession : NP_225065.1
Strain : Chlamydophila pneumoniae CWL029
Genome accession: NC_000922
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 987445 - 988728 bp
Length : 1284 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTGGATATAAAAATTATACGCAAGACTCCCGAAGAATGTGAAACTCGACTTCGTAAAAAAGATCCAAAAATTTCTTT
AGAACCTGTACTCTCCTTGGATAAAGAGGTCCGTCAACTCAAGACGGATTCAGAAACTTTACAAGCACAAAGACGCCTCT
TATCTCAAGATATACATAAAGCTAAAACGCAAGGGGTAGACGCGACAAACTTAATTCAAGAGGTAGAGACTCTTGCTGCG
GATCTTGAAAAAATTGAGCAGCACCTCGATCAAAAAAACGCTCAACTACATGAATTGCTGAGCCATCTTCCTAATTACCC
TGCTGACGACATTCCTGTATCCGAGGACAAAGCGGGAAATCAAGTCATTAAAAGTGTTGGGGACCTTCCTATATTTTCCT
TTCCTCCGAAGCATCACTTAGAGCTAAATCAGGAGTTAGACATCTTAGATTTCCAAGCAGCAGCAAAAACGACAGGATCA
GGATGGCCTGCTTATAAAAATCGTGGTGTTCTTCTGGAATGGGCTCTTCTTACGTATATGTTACAGAAGCAAGCAGCTCA
TGGATTTCAGCTCTGGCTTCCCCCCTTATTAGTGAAGAAAGAAATTTTATTTGGCTCTGGGCAGATTCCGAAATTTGATG
GACAATACTATCGTGTTGAGGACGGAGAGCAGTATCTCTATCTGATCCCCACTGCGGAAGTCGTTCTTAATGGGTTTCGT
TCCCAAGACATTTTAACAGAAAAAGAACTTCCTCTTTACTATGCTGCGTGCACTCCGTGCTTCCGAAGAGAAGCAGGTGC
TGCAGGAGCTCAAGAGAGAGGACTTGTGCGGGTGCATCAATTCCATAAGGTAGAAATGTTTGCCTTTACAACACCCAATC
AAGATGATATTGCTTATGAAAAAATGCTTAGTATTGTTGAAGAAATGCTGACAGAGCTCAAGTTGCCTTATCGTCTTTCT
TTGCTTTCTACGGGGGATATGTCTTTTACAGCATCCAAGACTATAGATGCTGAGGTCTGGTTGCCAGGACAAAAAGCTTT
TTATGAAGTGTCTTCTATTTCTCAGTGTACGGATTTCCAATCGCGGCGCTCTGGGACTCGCTATAAAGATAGCCAAGGGA
AACTACAGTTTGTTCATACTCTTAACGGTTCAGGTCTGGCAACACCACGTCTCTTGGTAGCTATTTTAGAAAATAACCAA
CAAGCTGATGGCTCTGTGGTTATTCCTGAAGTCCTTCGTCCTTATTTAGGAGGGTTGGAGATTCTTCTTCCCAAAGACCA
GTGA

Protein sequence :
MLDIKIIRKTPEECETRLRKKDPKISLEPVLSLDKEVRQLKTDSETLQAQRRLLSQDIHKAKTQGVDATNLIQEVETLAA
DLEKIEQHLDQKNAQLHELLSHLPNYPADDIPVSEDKAGNQVIKSVGDLPIFSFPPKHHLELNQELDILDFQAAAKTTGS
GWPAYKNRGVLLEWALLTYMLQKQAAHGFQLWLPPLLVKKEILFGSGQIPKFDGQYYRVEDGEQYLYLIPTAEVVLNGFR
SQDILTEKELPLYYAACTPCFRREAGAAGAQERGLVRVHQFHKVEMFAFTTPNQDDIAYEKMLSIVEEMLTELKLPYRLS
LLSTGDMSFTASKTIDAEVWLPGQKAFYEVSSISQCTDFQSRRSGTRYKDSQGKLQFVHTLNGSGLATPRLLVAILENNQ
QADGSVVIPEVLRPYLGGLEILLPKDQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-77 43